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Protein

Ladinin-1

Gene

LAD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Anchoring filament protein which is a component of the basement membrane zone.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cadherin binding Source: BHF-UCL
  • structural molecule activity Source: ProtInc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ladinin-1
Short name:
Lad-1
Alternative name(s):
Linear IgA disease antigen
Short name:
LADA
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LAD1
Synonyms:LAD
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000159166.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6472 LAD1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
602314 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O00515

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Basement membrane, Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
3898

Open Targets

More...
OpenTargetsi
ENSG00000159166

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30263

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LAD1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000843491 – 517Ladinin-1Add BLAST517

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei38PhosphoserineCombined sources1
Modified residuei64PhosphoserineCombined sources1
Modified residuei78PhosphoserineBy similarity1
Modified residuei121PhosphoserineCombined sources1
Modified residuei123PhosphoserineCombined sources1
Modified residuei347PhosphoserineBy similarity1
Modified residuei356PhosphoserineCombined sources1
Modified residuei394PhosphoserineCombined sources1
Modified residuei424Omega-N-methylarginineCombined sources1
Modified residuei485PhosphoserineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O00515

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O00515

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O00515

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O00515

PeptideAtlas

More...
PeptideAtlasi
O00515

PRoteomics IDEntifications database

More...
PRIDEi
O00515

ProteomicsDB human proteome resource

More...
ProteomicsDBi
47951

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O00515

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O00515

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000159166 Expressed in 164 organ(s), highest expression level in esophagus mucosa

CleanEx database of gene expression profiles

More...
CleanExi
HS_LAD1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O00515 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O00515 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA007256
HPA028732

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110095, 6 interactors

Protein interaction database and analysis system

More...
IntActi
O00515, 5 interactors

Molecular INTeraction database

More...
MINTi
O00515

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000375829

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O00515

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati203 – 205SEK 13
Repeati209 – 211SEK 23
Repeati215 – 217SEK 33
Repeati221 – 223SEK 43
Repeati227 – 229SEK 53
Repeati239 – 241SEK 63
Repeati257 – 259SEK 73
Repeati269 – 271SEK 83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni203 – 2718 X SEK repeatsAdd BLAST69

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi28 – 35Poly-Arg8

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIRJ Eukaryota
ENOG410YZPA LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005256

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113274

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG006240

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O00515

Database of Orthologous Groups

More...
OrthoDBi
976869at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O00515

TreeFam database of animal gene trees

More...
TreeFami
TF335896

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017404 Ladinin_1

The PANTHER Classification System

More...
PANTHERi
PTHR12392 PTHR12392, 3 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038144 Ladinin_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

O00515-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVSRKDWSA LSSLARQRTL EDEEEQERER RRRHRNLSST TDDEAPRLSQ
60 70 80 90 100
NGDRQASASE RLPSVEEAEV PKPLPPASKD EDEDIQSILR TRQERRQRRQ
110 120 130 140 150
VVEAAQAPIQ ERLEAEEGRN SLSPVQATQK PLVSKKELEI PPRRRLSREQ
160 170 180 190 200
RGPWALEEES LVGREPEERK KGVPEKSPVL EKSSMPKKTA PEKSLVSDKT
210 220 230 240 250
SISEKVLASE KTSLSEKIAV SEKRNSSEKK SVLEKTSVSE KSLAPGMALG
260 270 280 290 300
SGRRLVSEKA SIFEKALASE KSPTADAKPA PKRATASEQP LAQEPPASGG
310 320 330 340 350
SPATTKEQRG RALPGKNLPS LAKQGASDPP TVASRLPPVT LQVKIPSKEE
360 370 380 390 400
EADMSSPTQR TYSSSLKRSS PRTISFRMKP KKENSETTLT RSASMKLPDN
410 420 430 440 450
TVKLGEKLER YHTAIRRSES VKSRGLPCTE LFVAPVGVAS KRHLFEKELA
460 470 480 490 500
GQSRAEPASS RKENLRLSGV VTSRLNLWIS RTQESGDQDP QEAQKASSAT
510
ERTQWGQKSD SSLDAEV
Length:517
Mass (Da):57,131
Last modified:September 23, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i622E81B9412A924B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PDI4E9PDI4_HUMAN
Ladinin-1
LAD1
531Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y901H0Y901_HUMAN
Ladinin-1
LAD1
192Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YYF6A0A0J9YYF6_HUMAN
Ladinin-1
LAD1
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YW63A0A0J9YW63_HUMAN
Ladinin-1
LAD1
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YVY2A0A0J9YVY2_HUMAN
Ladinin-1
LAD1
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD10849 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04653956A → S. Corresponds to variant dbSNP:rs3738281Ensembl.1
Natural variantiVAR_046540155A → P2 PublicationsCorresponds to variant dbSNP:rs1128316Ensembl.1
Natural variantiVAR_046541243L → P. Corresponds to variant dbSNP:rs12088790Ensembl.1
Natural variantiVAR_046542279P → Q. Corresponds to variant dbSNP:rs11805972Ensembl.1
Natural variantiVAR_046543323K → E. Corresponds to variant dbSNP:rs4128458Ensembl.1
Natural variantiVAR_046544503T → S. Corresponds to variant dbSNP:rs2275866Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U42408 mRNA Translation: AAB58817.1
U58994 Genomic DNA Translation: AAD10849.1 Sequence problems.
AK313388 mRNA Translation: BAG36186.1
BC009742 mRNA Translation: AAH09742.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1410.1

NCBI Reference Sequences

More...
RefSeqi
NP_005549.2, NM_005558.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.519035

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000391967; ENSP00000375829; ENSG00000159166

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3898

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:3898

UCSC genome browser

More...
UCSCi
uc001gwm.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U42408 mRNA Translation: AAB58817.1
U58994 Genomic DNA Translation: AAD10849.1 Sequence problems.
AK313388 mRNA Translation: BAG36186.1
BC009742 mRNA Translation: AAH09742.1
CCDSiCCDS1410.1
RefSeqiNP_005549.2, NM_005558.3
UniGeneiHs.519035

3D structure databases

ProteinModelPortaliO00515
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110095, 6 interactors
IntActiO00515, 5 interactors
MINTiO00515
STRINGi9606.ENSP00000375829

PTM databases

iPTMnetiO00515
PhosphoSitePlusiO00515

Polymorphism and mutation databases

BioMutaiLAD1

Proteomic databases

EPDiO00515
jPOSTiO00515
MaxQBiO00515
PaxDbiO00515
PeptideAtlasiO00515
PRIDEiO00515
ProteomicsDBi47951

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
3898
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000391967; ENSP00000375829; ENSG00000159166
GeneIDi3898
KEGGihsa:3898
UCSCiuc001gwm.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3898
DisGeNETi3898
EuPathDBiHostDB:ENSG00000159166.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
LAD1
HGNCiHGNC:6472 LAD1
HPAiHPA007256
HPA028732
MIMi602314 gene
neXtProtiNX_O00515
OpenTargetsiENSG00000159166
PharmGKBiPA30263

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIRJ Eukaryota
ENOG410YZPA LUCA
GeneTreeiENSGT00390000005256
HOGENOMiHOG000113274
HOVERGENiHBG006240
InParanoidiO00515
OrthoDBi976869at2759
PhylomeDBiO00515
TreeFamiTF335896

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
LAD1 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
LAD1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
3898

Protein Ontology

More...
PROi
PR:O00515

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000159166 Expressed in 164 organ(s), highest expression level in esophagus mucosa
CleanExiHS_LAD1
ExpressionAtlasiO00515 baseline and differential
GenevisibleiO00515 HS

Family and domain databases

InterProiView protein in InterPro
IPR017404 Ladinin_1
PANTHERiPTHR12392 PTHR12392, 3 hits
PIRSFiPIRSF038144 Ladinin_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLAD1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O00515
Secondary accession number(s): O95614, Q96GD8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: September 23, 2008
Last modified: January 16, 2019
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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