UniProtKB - O00222 (GRM8_HUMAN)
Protein
Metabotropic glutamate receptor 8
Gene
GRM8
Organism
Homo sapiens (Human)
Status
Functioni
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 156 | GlutamateBy similarity | 1 | |
Binding sitei | 227 | GlutamateBy similarity | 1 | |
Binding sitei | 309 | GlutamateBy similarity | 1 | |
Binding sitei | 401 | GlutamateBy similarity | 1 |
GO - Molecular functioni
- glutamate receptor activity Source: UniProtKB
- G protein-coupled receptor activity Source: UniProtKB
- group III metabotropic glutamate receptor activity Source: GO_Central
GO - Biological processi
- adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway Source: UniProtKB
- adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Source: UniProtKB
- G protein-coupled glutamate receptor signaling pathway Source: GO_Central
- G protein-coupled receptor signaling pathway Source: Reactome
- regulation of synaptic transmission, glutamatergic Source: GO_Central
- visual perception Source: ProtInc
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Biological process | Sensory transduction |
Enzyme and pathway databases
PathwayCommonsi | O00222 |
Reactomei | R-HSA-418594, G alpha (i) signalling events R-HSA-420499, Class C/3 (Metabotropic glutamate/pheromone receptors) |
Names & Taxonomyi
Protein namesi | Recommended name: Metabotropic glutamate receptor 8Short name: mGluR8 |
Gene namesi | Name:GRM8 Synonyms:GPRC1H, MGLUR8 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4600, GRM8 |
MIMi | 601116, gene |
neXtProti | NX_O00222 |
VEuPathDBi | HostDB:ENSG00000179603.17 |
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
- plasma membrane Source: Reactome
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 34 – 583 | ExtracellularSequence analysisAdd BLAST | 550 | |
Transmembranei | 584 – 608 | Helical; Name=1Sequence analysisAdd BLAST | 25 | |
Topological domaini | 609 – 620 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 621 – 641 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 642 – 647 | ExtracellularSequence analysis | 6 | |
Transmembranei | 648 – 668 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 669 – 695 | CytoplasmicSequence analysisAdd BLAST | 27 | |
Transmembranei | 696 – 716 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 717 – 746 | ExtracellularSequence analysisAdd BLAST | 30 | |
Transmembranei | 747 – 768 | Helical; Name=5Sequence analysisAdd BLAST | 22 | |
Topological domaini | 769 – 781 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 782 – 803 | Helical; Name=6Sequence analysisAdd BLAST | 22 | |
Topological domaini | 804 – 818 | ExtracellularSequence analysisAdd BLAST | 15 | |
Transmembranei | 819 – 843 | Helical; Name=7Sequence analysisAdd BLAST | 25 | |
Topological domaini | 844 – 908 | CytoplasmicSequence analysisAdd BLAST | 65 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 2918 |
OpenTargetsi | ENSG00000179603 |
PharmGKBi | PA28997 |
Miscellaneous databases
Pharosi | O00222, Tchem |
Chemistry databases
ChEMBLi | CHEMBL3228 |
DrugBanki | DB00142, Glutamic acid |
DrugCentrali | O00222 |
GuidetoPHARMACOLOGYi | 296 |
Genetic variation databases
BioMutai | GRM8 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 33 | Sequence analysisAdd BLAST | 33 | |
ChainiPRO_0000012941 | 34 – 908 | Metabotropic glutamate receptor 8Add BLAST | 875 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 64 ↔ 106 | By similarity | ||
Glycosylationi | 95 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 246 ↔ 534 | By similarity | ||
Glycosylationi | 298 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 369 ↔ 384 | By similarity | ||
Disulfide bondi | 424 ↔ 431 | By similarity | ||
Glycosylationi | 452 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 480 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 516 ↔ 535 | By similarity | ||
Disulfide bondi | 520 ↔ 538 | By similarity | ||
Disulfide bondi | 541 ↔ 553 | By similarity | ||
Disulfide bondi | 556 ↔ 569 | By similarity | ||
Glycosylationi | 565 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Cross-linki | 882 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity |
Keywords - PTMi
Disulfide bond, Glycoprotein, Isopeptide bond, Ubl conjugationProteomic databases
PaxDbi | O00222 |
PeptideAtlasi | O00222 |
PRIDEi | O00222 |
ProteomicsDBi | 47792 [O00222-1] 47793 [O00222-2] 47794 [O00222-3] |
PTM databases
GlyGeni | O00222, 5 sites |
iPTMneti | O00222 |
PhosphoSitePlusi | O00222 |
Expressioni
Gene expression databases
Bgeei | ENSG00000179603, Expressed in anterior cingulate cortex and 167 other tissues |
ExpressionAtlasi | O00222, baseline and differential |
Genevisiblei | O00222, HS |
Organism-specific databases
HPAi | ENSG00000179603, Tissue enhanced (brain, liver) |
Interactioni
Subunit structurei
Interacts with PICK1.
By similarityProtein-protein interaction databases
BioGRIDi | 109175, 1 interactor |
CORUMi | O00222 |
IntActi | O00222, 1 interactor |
STRINGi | 9606.ENSP00000344173 |
Chemistry databases
BindingDBi | O00222 |
Miscellaneous databases
RNActi | O00222, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | O00222 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 177 – 179 | Glutamate bindingBy similarity | 3 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 3 family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1056, Eukaryota |
GeneTreei | ENSGT01010000222245 |
HOGENOMi | CLU_005389_0_0_1 |
InParanoidi | O00222 |
OMAi | TQKGNDR |
OrthoDBi | 483746at2759 |
PhylomeDBi | O00222 |
TreeFami | TF313240 |
Family and domain databases
Gene3Di | 2.10.50.30, 1 hit |
InterProi | View protein in InterPro IPR001828, ANF_lig-bd_rcpt IPR000337, GPCR_3 IPR011500, GPCR_3_9-Cys_dom IPR038550, GPCR_3_9-Cys_sf IPR017978, GPCR_3_C IPR017979, GPCR_3_CS IPR000162, GPCR_3_mtglu_rcpt IPR000144, GPCR_3_mtglu_rcpt_8 IPR028082, Peripla_BP_I |
Pfami | View protein in Pfam PF00003, 7tm_3, 1 hit PF01094, ANF_receptor, 1 hit PF07562, NCD3G, 1 hit |
PRINTSi | PR00248, GPCRMGR PR01058, MTABOTROPC8R PR00593, MTABOTROPICR |
SUPFAMi | SSF53822, SSF53822, 1 hit |
PROSITEi | View protein in PROSITE PS00979, G_PROTEIN_RECEP_F3_1, 1 hit PS00980, G_PROTEIN_RECEP_F3_2, 1 hit PS00981, G_PROTEIN_RECEP_F3_3, 1 hit PS50259, G_PROTEIN_RECEP_F3_4, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
Isoform A (identifier: O00222-1) [UniParc]FASTAAdd to basket
Also known as: mGluR8a
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MVCEGKRSAS CPCFFLLTAK FYWILTMMQR THSQEYAHSI RVDGDIILGG
60 70 80 90 100
LFPVHAKGER GVPCGELKKE KGIHRLEAML YAIDQINKDP DLLSNITLGV
110 120 130 140 150
RILDTCSRDT YALEQSLTFV QALIEKDASD VKCANGDPPI FTKPDKISGV
160 170 180 190 200
IGAAASSVSI MVANILRLFK IPQISYASTA PELSDNTRYD FFSRVVPPDS
210 220 230 240 250
YQAQAMVDIV TALGWNYVST LASEGNYGES GVEAFTQISR EIGGVCIAQS
260 270 280 290 300
QKIPREPRPG EFEKIIKRLL ETPNARAVIM FANEDDIRRI LEAAKKLNQS
310 320 330 340 350
GHFLWIGSDS WGSKIAPVYQ QEEIAEGAVT ILPKRASIDG FDRYFRSRTL
360 370 380 390 400
ANNRRNVWFA EFWEENFGCK LGSHGKRNSH IKKCTGLERI ARDSSYEQEG
410 420 430 440 450
KVQFVIDAVY SMAYALHNMH KDLCPGYIGL CPRMSTIDGK ELLGYIRAVN
460 470 480 490 500
FNGSAGTPVT FNENGDAPGR YDIFQYQITN KSTEYKVIGH WTNQLHLKVE
510 520 530 540 550
DMQWAHREHT HPASVCSLPC KPGERKKTVK GVPCCWHCER CEGYNYQVDE
560 570 580 590 600
LSCELCPLDQ RPNMNRTGCQ LIPIIKLEWH SPWAVVPVFV AILGIIATTF
610 620 630 640 650
VIVTFVRYND TPIVRASGRE LSYVLLTGIF LCYSITFLMI AAPDTIICSF
660 670 680 690 700
RRVFLGLGMC FSYAALLTKT NRIHRIFEQG KKSVTAPKFI SPASQLVITF
710 720 730 740 750
SLISVQLLGV FVWFVVDPPH IIIDYGEQRT LDPEKARGVL KCDISDLSLI
760 770 780 790 800
CSLGYSILLM VTCTVYAIKT RGVPETFNEA KPIGFTMYTT CIIWLAFIPI
810 820 830 840 850
FFGTAQSAEK MYIQTTTLTV SMSLSASVSL GMLYMPKVYI IIFHPEQNVQ
860 870 880 890 900
KRKRSFKAVV TAATMQSKLI QKGNDRPNGE VKSELCESLE TNTSSTKTTY
ISYSNHSI
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0A0MT06 | A0A0A0MT06_HUMAN | Metabotropic glutamate receptor 8 | GRM8 | 416 | Annotation score: | ||
E7ETK3 | E7ETK3_HUMAN | Metabotropic glutamate receptor 8 | GRM8 | 293 | Annotation score: | ||
H7C4V5 | H7C4V5_HUMAN | Metabotropic glutamate receptor 8 | GRM8 | 91 | Annotation score: | ||
C9J7I1 | C9J7I1_HUMAN | Metabotropic glutamate receptor 8 | GRM8 | 20 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 194 | R → A in AAB72040 (PubMed:9299241).Curated | 1 | |
Sequence conflicti | 460 | T → I in AAB72040 (PubMed:9299241).Curated | 1 | |
Sequence conflicti | 591 | A → V in ABY87924 (Ref. 5) Curated | 1 | |
Sequence conflicti | 642 | A → G in AAB72040 (PubMed:9299241).Curated | 1 | |
Sequence conflicti | 904 | S → T in AAB72040 (PubMed:9299241).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_014446 | 10 | S → C1 PublicationCorresponds to variant dbSNP:rs769194EnsemblClinVar. | 1 | |
Natural variantiVAR_014447 | 21 | F → C. Corresponds to variant dbSNP:rs769202EnsemblClinVar. | 1 | |
Natural variantiVAR_049278 | 265 | I → T1 PublicationCorresponds to variant dbSNP:rs17150343EnsemblClinVar. | 1 | |
Natural variantiVAR_054752 | 343 | R → Q1 PublicationCorresponds to variant dbSNP:rs13309334Ensembl. | 1 | |
Natural variantiVAR_054477 | 362 | F → Y1 PublicationCorresponds to variant dbSNP:rs78124913Ensembl. | 1 | |
Natural variantiVAR_054478 | 368 | G → D1 PublicationCorresponds to variant dbSNP:rs78947184Ensembl. | 1 | |
Natural variantiVAR_014448 | 392 | R → Q. Corresponds to variant dbSNP:rs2234947Ensembl. | 1 | |
Natural variantiVAR_054479 | 430 | L → F1 PublicationCorresponds to variant dbSNP:rs75863532Ensembl. | 1 | |
Natural variantiVAR_014449 | 548 | V → G. Corresponds to variant dbSNP:rs2234948Ensembl. | 1 | |
Natural variantiVAR_054753 | 768 | I → N1 PublicationCorresponds to variant dbSNP:rs1051433Ensembl. | 1 | |
Natural variantiVAR_054754 | 902 | S → I. Corresponds to variant dbSNP:rs10225567Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_002033 | 454 – 501 | SAGTP…LKVED → CRRGIQMSLPWPTLFTPSFS SSWAVLALLSLLMKTEMLLD VMISSSIK in isoform C. 1 PublicationAdd BLAST | 48 | |
Alternative sequenceiVSP_002034 | 502 – 908 | Missing in isoform C. 1 PublicationAdd BLAST | 407 | |
Alternative sequenceiVSP_002032 | 893 – 908 | TSSTK…SNHSI → SKSSVEFPMVKSGSTS in isoform B. 2 PublicationsAdd BLAST | 16 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U95025 mRNA Translation: AAB72040.1 U92459 mRNA Translation: AAB51764.1 AJ236921 mRNA Translation: CAB36968.1 AJ236922 mRNA Translation: CAB36969.1 AY608335 mRNA Translation: AAT37959.1 EU432125 mRNA Translation: ABY87924.1 EU368948 Genomic DNA Translation: ABY59657.1 CH236947 Genomic DNA Translation: EAL24322.1 BC093725 mRNA Translation: AAH93725.1 BC101675 mRNA Translation: AAI01676.1 |
CCDSi | CCDS47696.1 [O00222-2] CCDS5794.1 [O00222-1] |
RefSeqi | NP_000836.2, NM_000845.2 [O00222-1] NP_001120795.1, NM_001127323.1 [O00222-2] XP_006716001.1, XM_006715938.3 XP_011514393.1, XM_011516091.1 XP_011514394.1, XM_011516092.2 XP_016867563.1, XM_017012074.1 |
Genome annotation databases
Ensembli | ENST00000339582; ENSP00000344173; ENSG00000179603 [O00222-1] ENST00000341617; ENSP00000345747; ENSG00000179603 [O00222-3] ENST00000358373; ENSP00000351142; ENSG00000179603 [O00222-2] ENST00000472701; ENSP00000419832; ENSG00000179603 [O00222-2] |
GeneIDi | 2918 |
KEGGi | hsa:2918 |
UCSCi | uc003vlr.3, human [O00222-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
NIEHS-SNPs |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U95025 mRNA Translation: AAB72040.1 U92459 mRNA Translation: AAB51764.1 AJ236921 mRNA Translation: CAB36968.1 AJ236922 mRNA Translation: CAB36969.1 AY608335 mRNA Translation: AAT37959.1 EU432125 mRNA Translation: ABY87924.1 EU368948 Genomic DNA Translation: ABY59657.1 CH236947 Genomic DNA Translation: EAL24322.1 BC093725 mRNA Translation: AAH93725.1 BC101675 mRNA Translation: AAI01676.1 |
CCDSi | CCDS47696.1 [O00222-2] CCDS5794.1 [O00222-1] |
RefSeqi | NP_000836.2, NM_000845.2 [O00222-1] NP_001120795.1, NM_001127323.1 [O00222-2] XP_006716001.1, XM_006715938.3 XP_011514393.1, XM_011516091.1 XP_011514394.1, XM_011516092.2 XP_016867563.1, XM_017012074.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6BSZ | X-ray | 2.65 | A/B | 37-514 | [»] | |
6BT5 | X-ray | 2.92 | A/B | 37-514 | [»] | |
6E5V | X-ray | 2.95 | A/B | 2-508 | [»] | |
SMRi | O00222 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 109175, 1 interactor |
CORUMi | O00222 |
IntActi | O00222, 1 interactor |
STRINGi | 9606.ENSP00000344173 |
Chemistry databases
BindingDBi | O00222 |
ChEMBLi | CHEMBL3228 |
DrugBanki | DB00142, Glutamic acid |
DrugCentrali | O00222 |
GuidetoPHARMACOLOGYi | 296 |
Protein family/group databases
GPCRDBi | Search... |
PTM databases
GlyGeni | O00222, 5 sites |
iPTMneti | O00222 |
PhosphoSitePlusi | O00222 |
Genetic variation databases
BioMutai | GRM8 |
Proteomic databases
PaxDbi | O00222 |
PeptideAtlasi | O00222 |
PRIDEi | O00222 |
ProteomicsDBi | 47792 [O00222-1] 47793 [O00222-2] 47794 [O00222-3] |
Protocols and materials databases
Antibodypediai | 17706, 364 antibodies |
Genome annotation databases
Ensembli | ENST00000339582; ENSP00000344173; ENSG00000179603 [O00222-1] ENST00000341617; ENSP00000345747; ENSG00000179603 [O00222-3] ENST00000358373; ENSP00000351142; ENSG00000179603 [O00222-2] ENST00000472701; ENSP00000419832; ENSG00000179603 [O00222-2] |
GeneIDi | 2918 |
KEGGi | hsa:2918 |
UCSCi | uc003vlr.3, human [O00222-1] |
Organism-specific databases
CTDi | 2918 |
DisGeNETi | 2918 |
GeneCardsi | GRM8 |
HGNCi | HGNC:4600, GRM8 |
HPAi | ENSG00000179603, Tissue enhanced (brain, liver) |
MIMi | 601116, gene |
neXtProti | NX_O00222 |
OpenTargetsi | ENSG00000179603 |
PharmGKBi | PA28997 |
VEuPathDBi | HostDB:ENSG00000179603.17 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1056, Eukaryota |
GeneTreei | ENSGT01010000222245 |
HOGENOMi | CLU_005389_0_0_1 |
InParanoidi | O00222 |
OMAi | TQKGNDR |
OrthoDBi | 483746at2759 |
PhylomeDBi | O00222 |
TreeFami | TF313240 |
Enzyme and pathway databases
PathwayCommonsi | O00222 |
Reactomei | R-HSA-418594, G alpha (i) signalling events R-HSA-420499, Class C/3 (Metabotropic glutamate/pheromone receptors) |
Miscellaneous databases
BioGRID-ORCSi | 2918, 8 hits in 872 CRISPR screens |
ChiTaRSi | GRM8, human |
GeneWikii | Metabotropic_glutamate_receptor_8 |
GenomeRNAii | 2918 |
Pharosi | O00222, Tchem |
PROi | PR:O00222 |
RNActi | O00222, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000179603, Expressed in anterior cingulate cortex and 167 other tissues |
ExpressionAtlasi | O00222, baseline and differential |
Genevisiblei | O00222, HS |
Family and domain databases
Gene3Di | 2.10.50.30, 1 hit |
InterProi | View protein in InterPro IPR001828, ANF_lig-bd_rcpt IPR000337, GPCR_3 IPR011500, GPCR_3_9-Cys_dom IPR038550, GPCR_3_9-Cys_sf IPR017978, GPCR_3_C IPR017979, GPCR_3_CS IPR000162, GPCR_3_mtglu_rcpt IPR000144, GPCR_3_mtglu_rcpt_8 IPR028082, Peripla_BP_I |
Pfami | View protein in Pfam PF00003, 7tm_3, 1 hit PF01094, ANF_receptor, 1 hit PF07562, NCD3G, 1 hit |
PRINTSi | PR00248, GPCRMGR PR01058, MTABOTROPC8R PR00593, MTABOTROPICR |
SUPFAMi | SSF53822, SSF53822, 1 hit |
PROSITEi | View protein in PROSITE PS00979, G_PROTEIN_RECEP_F3_1, 1 hit PS00980, G_PROTEIN_RECEP_F3_2, 1 hit PS00981, G_PROTEIN_RECEP_F3_3, 1 hit PS50259, G_PROTEIN_RECEP_F3_4, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GRM8_HUMAN | |
Accessioni | O00222Primary (citable) accession number: O00222 Secondary accession number(s): A4D0Y3 Q6J165 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | December 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 186 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries - Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families