UniProtKB - O00139 (KIF2A_HUMAN)
Kinesin-like protein KIF2A
KIF2A
Functioni
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
3 PublicationsMiscellaneous
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 313 – 320 | ATP | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ATP hydrolysis activity Source: GO_Central
- cytoskeletal motor activity Source: ProtInc
- microtubule binding Source: ARUK-UCL
- microtubule motor activity Source: GO_Central
GO - Biological processi
- cell differentiation Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- microtubule-based movement Source: GO_Central
- microtubule cytoskeleton organization Source: ARUK-UCL
- microtubule depolymerization Source: ARUK-UCL
- mitotic spindle assembly Source: UniProtKB
- mitotic spindle organization Source: UniProtKB
- nervous system development Source: UniProtKB-KW
- regulation of cell migration Source: ARUK-UCL
Keywordsi
Molecular function | Developmental protein, Motor protein |
Biological process | Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
PathwayCommonsi | O00139 |
Reactomei | R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-2132295, MHC class II antigen presentation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-5663220, RHO GTPases Activate Formins R-HSA-6811434, COPI-dependent Golgi-to-ER retrograde traffic R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983189, Kinesins |
SignaLinki | O00139 |
SIGNORi | O00139 |
Names & Taxonomyi
Protein namesi | Recommended name: Kinesin-like protein KIF2AAlternative name(s): Kinesin-2 Short name: hK2 |
Gene namesi | Name:KIF2A Synonyms:KIF2, KNS2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6318, KIF2A |
MIMi | 602591, gene |
neXtProti | NX_O00139 |
VEuPathDBi | HostDB:ENSG00000068796 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Cytoskeleton
Note: Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.
Cytoskeleton
- centriole Source: GO_Central
- centrosome Source: UniProtKB
- kinesin complex Source: GO_Central
- microtubule Source: UniProtKB-KW
- spindle Source: GO_Central
- spindle pole Source: UniProtKB-SubCell
Cytosol
- cytosol Source: Reactome
Nucleus
- nuclear body Source: HPA
- nucleolus Source: HPA
- nucleoplasm Source: HPA
Other locations
- centriolar subdistal appendage Source: GO_Central
- cytoplasm Source: ARUK-UCL
- membrane Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, MicrotubulePathology & Biotechi
Involvement in diseasei
Cortical dysplasia, complex, with other brain malformations 3 (CDCBM3)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_070575 | 317 | S → N in CDCBM3; results in abnormal cellular localization with predominant decoration of microtubules rather than diffuse punctiform cytoplasmic and nuclear distribution as observed for wild-type protein. 1 PublicationCorresponds to variant dbSNP:rs587777034EnsemblClinVar. | 1 | |
Natural variantiVAR_070576 | 321 | H → D in CDCBM3; results in abnormal cellular localization with predominant decoration of microtubules rather than diffuse punctiform cytoplasmic and nuclear distribution as observed for wild-type protein. 1 PublicationCorresponds to variant dbSNP:rs587777033EnsemblClinVar. | 1 |
Keywords - Diseasei
Disease variant, LissencephalyOrganism-specific databases
DisGeNETi | 3796 |
MalaCardsi | KIF2A |
MIMi | 615411, phenotype |
OpenTargetsi | ENSG00000068796 |
PharmGKBi | PA162393356 |
Miscellaneous databases
Pharosi | O00139, Tbio |
Genetic variation databases
BioMutai | KIF2A |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000125414 | 1 – 706 | Kinesin-like protein KIF2AAdd BLAST | 706 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Modified residuei | 75 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 78 | PhosphothreonineCombined sources | 1 | ||
Modified residuei | 97 | PhosphothreonineCombined sources | 1 | ||
Modified residuei | 100 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 102 | N6-acetyllysineBy similarity | 1 | ||
Modified residuei | 135 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 140 | PhosphoserineCombined sources | 1 | ||
Isoform 4 (identifier: O00139-4) | |||||
Modified residuei | 556 | PhosphoserineBy similarity | 1 | ||
Modified residuei | 573 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | O00139 |
jPOSTi | O00139 |
MassIVEi | O00139 |
MaxQBi | O00139 |
PeptideAtlasi | O00139 |
PRIDEi | O00139 |
ProteomicsDBi | 19159 47722 [O00139-3] 47723 [O00139-1] 47724 [O00139-2] 47725 [O00139-4] |
PTM databases
GlyGeni | O00139, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | O00139 |
PhosphoSitePlusi | O00139 |
Expressioni
Gene expression databases
Bgeei | ENSG00000068796, Expressed in corpus callosum and 235 other tissues |
ExpressionAtlasi | O00139, baseline and differential |
Genevisiblei | O00139, HS |
Organism-specific databases
HPAi | ENSG00000068796, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with AURKA, PSRC1 and PLK1.
3 PublicationsBinary interactionsi
O00139
With | #Exp. | IntAct |
---|---|---|
FAM13C [Q8NE31] | 4 | EBI-2692369,EBI-751248 |
LARP1B [Q659C4] | 3 | EBI-2692369,EBI-3940258 |
MRPL53 [Q96EL3] | 3 | EBI-2692369,EBI-2513715 |
Isoform 1 [O00139-1]
GO - Molecular functioni
- microtubule binding Source: ARUK-UCL
Protein-protein interaction databases
BioGRIDi | 109997, 148 interactors |
DIPi | DIP-56112N |
IntActi | O00139, 68 interactors |
MINTi | O00139 |
STRINGi | 9606.ENSP00000385000 |
Miscellaneous databases
RNActi | O00139, protein |
Structurei
Secondary structure
3D structure databases
SASBDBi | O00139 |
SMRi | O00139 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O00139 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 223 – 553 | Kinesin motorPROSITE-ProRule annotationAdd BLAST | 331 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 217 | GlobularSequence analysisAdd BLAST | 217 | |
Regioni | 66 – 139 | DisorderedSequence analysisAdd BLAST | 74 | |
Regioni | 165 – 186 | DisorderedSequence analysisAdd BLAST | 22 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 660 – 699 | Sequence analysisAdd BLAST | 40 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 120 – 139 | Polar residuesSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG0246, Eukaryota |
GeneTreei | ENSGT00940000155570 |
HOGENOMi | CLU_001485_19_1_1 |
InParanoidi | O00139 |
OMAi | PMGSTKI |
OrthoDBi | 418348at2759 |
PhylomeDBi | O00139 |
TreeFami | TF105222 |
Family and domain databases
Gene3Di | 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR027640, Kinesin-like_fam IPR019821, Kinesin_motor_CS IPR001752, Kinesin_motor_dom IPR036961, Kinesin_motor_dom_sf IPR027417, P-loop_NTPase |
PANTHERi | PTHR24115, PTHR24115, 1 hit |
Pfami | View protein in Pfam PF00225, Kinesin, 1 hit |
PRINTSi | PR00380, KINESINHEAVY |
SMARTi | View protein in SMART SM00129, KISc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00411, KINESIN_MOTOR_1, 1 hit PS50067, KINESIN_MOTOR_2, 1 hit |
s (5+)i Sequence
Sequence statusi: Complete.
This entry describes 5 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 5 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MATANFGKIQ IGIYVEIKRS DGRIHQAMVT SLNEDNESVT VEWIENGDTK
60 70 80 90 100
GKEIDLESIF SLNPDLVPDE EIEPSPETPP PPASSAKVNK IVKNRRTVAS
110 120 130 140 150
IKNDPPSRDN RVVGSARARP SQFPEQSSSA QQNGSVSDIS PVQAAKKEFG
160 170 180 190 200
PPSRRKSNCV KEVEKLQEKR EKRRLQQQEL REKRAQDVDA TNPNYEIMCM
210 220 230 240 250
IRDFRGSLDY RPLTTADPID EHRICVCVRK RPLNKKETQM KDLDVITIPS
260 270 280 290 300
KDVVMVHEPK QKVDLTRYLE NQTFRFDYAF DDSAPNEMVY RFTARPLVET
310 320 330 340 350
IFERGMATCF AYGQTGSGKT HTMGGDFSGK NQDCSKGIYA LAARDVFLML
360 370 380 390 400
KKPNYKKLEL QVYATFFEIY SGKVFDLLNR KTKLRVLEDG KQQVQVVGLQ
410 420 430 440 450
EREVKCVEDV LKLIDIGNSC RTSGQTSANA HSSRSHAVFQ IILRRKGKLH
460 470 480 490 500
GKFSLIDLAG NERGADTSSA DRQTRLEGAE INKSLLALKE CIRALGRNKP
510 520 530 540 550
HTPFRASKLT QVLRDSFIGE NSRTCMIATI SPGMASCENT LNTLRYANRV
560 570 580 590 600
KELTVDPTAA GDVRPIMHHP PNQIDDLETQ WGVGSSPQRD DLKLLCEQNE
610 620 630 640 650
EEVSPQLFTF HEAVSQMVEM EEQVVEDHRA VFQESIRWLE DEKALLEMTE
660 670 680 690 700
EVDYDVDSYA TQLEAILEQK IDILTELRDK VKSFRAALQE EEQASKQINP
KRPRAL
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A6Q8PFA6 | A0A6Q8PFA6_HUMAN | Kinesin-like protein | KIF2A | 687 | Annotation score: | ||
A0A6Q8PG37 | A0A6Q8PG37_HUMAN | Kinesin-like protein | KIF2A | 717 | Annotation score: | ||
A0A6Q8PGH7 | A0A6Q8PGH7_HUMAN | Kinesin-like protein | KIF2A | 685 | Annotation score: | ||
A0A6Q8PH57 | A0A6Q8PH57_HUMAN | Kinesin-like protein | KIF2A | 725 | Annotation score: | ||
D6R9M0 | D6R9M0_HUMAN | Kinesin-like protein | KIF2A | 519 | Annotation score: | ||
A0A6Q8PGG1 | A0A6Q8PGG1_HUMAN | Kinesin-like protein KIF2A | KIF2A | 590 | Annotation score: | ||
H0Y8H2 | H0Y8H2_HUMAN | Kinesin-like protein KIF2A | KIF2A | 130 | Annotation score: | ||
D6RD93 | D6RD93_HUMAN | Kinesin-like protein KIF2A | KIF2A | 80 | Annotation score: | ||
A0A669KBE9 | A0A669KBE9_HUMAN | Kinesin-like protein KIF2A | KIF2A | 40 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 143 | Q → H in AAP84320 (Ref. 7) Curated | 1 | |
Sequence conflicti | 153 | S → SHLFFSA in AAP84320 (Ref. 7) Curated | 1 | |
Sequence conflicti | 295 | R → K in CAA69621 (PubMed:9177777).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_070575 | 317 | S → N in CDCBM3; results in abnormal cellular localization with predominant decoration of microtubules rather than diffuse punctiform cytoplasmic and nuclear distribution as observed for wild-type protein. 1 PublicationCorresponds to variant dbSNP:rs587777034EnsemblClinVar. | 1 | |
Natural variantiVAR_070576 | 321 | H → D in CDCBM3; results in abnormal cellular localization with predominant decoration of microtubules rather than diffuse punctiform cytoplasmic and nuclear distribution as observed for wild-type protein. 1 PublicationCorresponds to variant dbSNP:rs587777033EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_028374 | 1 – 27 | Missing in isoform 1 and isoform 2. 3 PublicationsAdd BLAST | 27 | |
Alternative sequenceiVSP_047373 | 1 – 21 | MATAN…IKRSD → M in isoform 5. CuratedAdd BLAST | 21 | |
Alternative sequenceiVSP_028375 | 134 – 153 | GSVSD…FGPPS → A in isoform 2. 2 PublicationsAdd BLAST | 20 | |
Alternative sequenceiVSP_028376 | 552 | E → EFGISPSDIPFSQGSGSRPD LSPSYEYDDFSPSVTRVKE in isoform 4. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y08319 mRNA Translation: CAA69621.1 AK302270 mRNA Translation: BAG63616.1 EF560716 mRNA Translation: ABQ59026.1 EF560728 mRNA Translation: ABQ59038.1 AC016637 Genomic DNA No translation available. AC034242 Genomic DNA No translation available. AC114982 Genomic DNA No translation available. CH471137 Genomic DNA Translation: EAW51388.1 CH471137 Genomic DNA Translation: EAW51390.1 BC031828 mRNA Translation: AAH31828.1 AY317140 mRNA Translation: AAP84320.1 Different initiation. |
CCDSi | CCDS3980.2 [O00139-3] CCDS47216.1 [O00139-4] CCDS58949.1 [O00139-1] |
RefSeqi | NP_001091981.1, NM_001098511.2 [O00139-4] NP_001230881.1, NM_001243952.1 [O00139-1] NP_004511.2, NM_004520.4 [O00139-3] |
Genome annotation databases
Ensembli | ENST00000381103; ENSP00000370493; ENSG00000068796 [O00139-1] ENST00000401507; ENSP00000385622; ENSG00000068796 ENST00000407818; ENSP00000385000; ENSG00000068796 [O00139-4] ENST00000506857; ENSP00000423772; ENSG00000068796 [O00139-2] ENST00000676413; ENSP00000502125; ENSG00000068796 [O00139-1] |
GeneIDi | 3796 |
KEGGi | hsa:3796 |
MANE-Selecti | ENST00000407818.8; ENSP00000385000.3; NM_001098511.3; NP_001091981.1 [O00139-4] |
UCSCi | uc003jsx.5, human [O00139-3] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y08319 mRNA Translation: CAA69621.1 AK302270 mRNA Translation: BAG63616.1 EF560716 mRNA Translation: ABQ59026.1 EF560728 mRNA Translation: ABQ59038.1 AC016637 Genomic DNA No translation available. AC034242 Genomic DNA No translation available. AC114982 Genomic DNA No translation available. CH471137 Genomic DNA Translation: EAW51388.1 CH471137 Genomic DNA Translation: EAW51390.1 BC031828 mRNA Translation: AAH31828.1 AY317140 mRNA Translation: AAP84320.1 Different initiation. |
CCDSi | CCDS3980.2 [O00139-3] CCDS47216.1 [O00139-4] CCDS58949.1 [O00139-1] |
RefSeqi | NP_001091981.1, NM_001098511.2 [O00139-4] NP_001230881.1, NM_001243952.1 [O00139-1] NP_004511.2, NM_004520.4 [O00139-3] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2GRY | X-ray | 2.35 | A | 153-553 | [»] | |
6BBN | X-ray | 3.51 | E | 153-553 | [»] | |
SASBDBi | O00139 | |||||
SMRi | O00139 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 109997, 148 interactors |
DIPi | DIP-56112N |
IntActi | O00139, 68 interactors |
MINTi | O00139 |
STRINGi | 9606.ENSP00000385000 |
PTM databases
GlyGeni | O00139, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | O00139 |
PhosphoSitePlusi | O00139 |
Genetic variation databases
BioMutai | KIF2A |
Proteomic databases
EPDi | O00139 |
jPOSTi | O00139 |
MassIVEi | O00139 |
MaxQBi | O00139 |
PeptideAtlasi | O00139 |
PRIDEi | O00139 |
ProteomicsDBi | 19159 47722 [O00139-3] 47723 [O00139-1] 47724 [O00139-2] 47725 [O00139-4] |
Protocols and materials databases
Antibodypediai | 1353, 213 antibodies from 28 providers |
DNASUi | 3796 |
Genome annotation databases
Ensembli | ENST00000381103; ENSP00000370493; ENSG00000068796 [O00139-1] ENST00000401507; ENSP00000385622; ENSG00000068796 ENST00000407818; ENSP00000385000; ENSG00000068796 [O00139-4] ENST00000506857; ENSP00000423772; ENSG00000068796 [O00139-2] ENST00000676413; ENSP00000502125; ENSG00000068796 [O00139-1] |
GeneIDi | 3796 |
KEGGi | hsa:3796 |
MANE-Selecti | ENST00000407818.8; ENSP00000385000.3; NM_001098511.3; NP_001091981.1 [O00139-4] |
UCSCi | uc003jsx.5, human [O00139-3] |
Organism-specific databases
CTDi | 3796 |
DisGeNETi | 3796 |
GeneCardsi | KIF2A |
HGNCi | HGNC:6318, KIF2A |
HPAi | ENSG00000068796, Low tissue specificity |
MalaCardsi | KIF2A |
MIMi | 602591, gene 615411, phenotype |
neXtProti | NX_O00139 |
OpenTargetsi | ENSG00000068796 |
PharmGKBi | PA162393356 |
VEuPathDBi | HostDB:ENSG00000068796 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0246, Eukaryota |
GeneTreei | ENSGT00940000155570 |
HOGENOMi | CLU_001485_19_1_1 |
InParanoidi | O00139 |
OMAi | PMGSTKI |
OrthoDBi | 418348at2759 |
PhylomeDBi | O00139 |
TreeFami | TF105222 |
Enzyme and pathway databases
PathwayCommonsi | O00139 |
Reactomei | R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-2132295, MHC class II antigen presentation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-5663220, RHO GTPases Activate Formins R-HSA-6811434, COPI-dependent Golgi-to-ER retrograde traffic R-HSA-68877, Mitotic Prometaphase R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983189, Kinesins |
SignaLinki | O00139 |
SIGNORi | O00139 |
Miscellaneous databases
BioGRID-ORCSi | 3796, 43 hits in 1053 CRISPR screens |
ChiTaRSi | KIF2A, human |
EvolutionaryTracei | O00139 |
GeneWikii | KIF2A |
GenomeRNAii | 3796 |
Pharosi | O00139, Tbio |
PROi | PR:O00139 |
RNActi | O00139, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000068796, Expressed in corpus callosum and 235 other tissues |
ExpressionAtlasi | O00139, baseline and differential |
Genevisiblei | O00139, HS |
Family and domain databases
Gene3Di | 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR027640, Kinesin-like_fam IPR019821, Kinesin_motor_CS IPR001752, Kinesin_motor_dom IPR036961, Kinesin_motor_dom_sf IPR027417, P-loop_NTPase |
PANTHERi | PTHR24115, PTHR24115, 1 hit |
Pfami | View protein in Pfam PF00225, Kinesin, 1 hit |
PRINTSi | PR00380, KINESINHEAVY |
SMARTi | View protein in SMART SM00129, KISc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00411, KINESIN_MOTOR_1, 1 hit PS50067, KINESIN_MOTOR_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | KIF2A_HUMAN | |
Accessioni | O00139Primary (citable) accession number: O00139 Secondary accession number(s): A5YM42 Q8N5Q7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | October 2, 2007 | |
Last modified: | February 23, 2022 | |
This is version 192 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 5
Human chromosome 5: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families