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Protein

Dephospho-CoA kinase

Gene

coaE

Organism
Thauera linaloolentis 47Lol = DSM 12138
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + 3'-dephospho-CoA = ADP + CoA.UniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in step 5 of the subpathway that synthesizes CoA from (R)-pantothenate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Type III pantothenate kinase (coaX)
  2. Coenzyme A biosynthesis bifunctional protein CoaBC (C666_06105)
  3. Coenzyme A biosynthesis bifunctional protein CoaBC (C666_06105)
  4. Phosphopantetheine adenylyltransferase (coaD)
  5. Dephospho-CoA kinase (coaE)
This subpathway is part of the pathway coenzyme A biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CoA from (R)-pantothenate, the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 25ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processCoenzyme A biosynthesisUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayi
UPA00241;UER00356

Names & Taxonomyi

Protein namesi
Recommended name:
Dephospho-CoA kinaseUniRule annotation (EC:2.7.1.24UniRule annotation)
Alternative name(s):
Dephosphocoenzyme A kinaseUniRule annotation
Gene namesi
Name:coaEUniRule annotationImported
ORF Names:C666_12900Imported
OrganismiThauera linaloolentis 47Lol = DSM 12138Imported
Taxonomic identifieri1123367 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesZoogloeaceaeThauera
Proteomesi
  • UP000013232 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the CoaE family.UniRule annotation

Phylogenomic databases

OrthoDBiPOG091H02KX

Family and domain databases

CDDicd02022 DPCK, 1 hit
HAMAPiMF_00376 Dephospho_CoA_kinase, 1 hit
InterProiView protein in InterPro
IPR001977 Depp_CoAkinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01121 CoaE, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00152 TIGR00152, 1 hit
PROSITEiView protein in PROSITE
PS51219 DPCK, 1 hit

Sequencei

Sequence statusi: Complete.

N6Y4R4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATAPPSPSR PFIVGLTGGI GSGKSAAAEL FVEHGAGLVD TDAIAHALTA
60 70 80 90 100
ADGAAMPAIH ARFGDAVIAA DGSLDRAAMR ARVFAQADAR QQLEAILHPM
110 120 130 140 150
IRDESARQCT TARGIYVILA VPLLVESGGY RTRCDRVCVV DCPPEIQVER
160 170 180 190 200
VRARSGLEEA QIRAIMATQA SRDQRLAAAD DVIDNGASLE YLRAQVAALH
210
SHYASLAARR A
Length:211
Mass (Da):22,208
Last modified:June 26, 2013 - v1
Checksum:i32EDF2B0DAD36101
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMXE01000052 Genomic DNA Translation: ENO86585.1
RefSeqiWP_004340066.1, NZ_JHYR01000007.1

Genome annotation databases

EnsemblBacteriaiENO86585; ENO86585; C666_12900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMXE01000052 Genomic DNA Translation: ENO86585.1
RefSeqiWP_004340066.1, NZ_JHYR01000007.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiENO86585; ENO86585; C666_12900

Phylogenomic databases

OrthoDBiPOG091H02KX

Enzyme and pathway databases

UniPathwayi
UPA00241;UER00356

Family and domain databases

CDDicd02022 DPCK, 1 hit
HAMAPiMF_00376 Dephospho_CoA_kinase, 1 hit
InterProiView protein in InterPro
IPR001977 Depp_CoAkinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01121 CoaE, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00152 TIGR00152, 1 hit
PROSITEiView protein in PROSITE
PS51219 DPCK, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiN6Y4R4_9RHOO
AccessioniPrimary (citable) accession number: N6Y4R4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: September 27, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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