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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Archaeoglobus sulfaticallidus PM70-1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation
Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processDNA replicationUniRule annotation

Enzyme and pathway databases

BioCyciASUL387631:G1HH6-1595-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
ORF Names:Asulf_01622Imported
OrganismiArchaeoglobus sulfaticallidus PM70-1Imported
Taxonomic identifieri387631 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000013307 Componenti: Chromosome

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliN0BH36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 95PCNA_NInterPro annotationAdd BLAST89
Domaini121 – 238PCNA_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

KOiK04802
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

N0BH36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDVVLNGEI LKTVSKAMVS LVSEARFHFK EEGLHSRAVD PANVAMVIVD
60 70 80 90 100
VPSSSFIKYE SEGDFVAGVD VNRIFDISKS IKNDDVVEMT INEESFIVKF
110 120 130 140 150
GSVKYSVSLI DPSAIRKEPR IPQIDLPAKI VMDAGEFKKA IVAADKISDH
160 170 180 190 200
VVFRTNEEGF FIEAEGDVDR ITFSLSDAEL AEFNRQEAKS MFSLEYLKEF
210 220 230 240
VKIASSGDVL TIRLGNDYPV RMVFEVAGGK VRVEYILAPR IEAE
Length:244
Mass (Da):27,136
Last modified:June 26, 2013 - v1
Checksum:i3B605801EE3A470A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP005290 Genomic DNA Translation: AGK61597.1
RefSeqiWP_015591195.1, NC_021169.1

Genome annotation databases

EnsemblBacteriaiAGK61597; AGK61597; Asulf_01622
GeneIDi15393257
KEGGiast:Asulf_01622

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP005290 Genomic DNA Translation: AGK61597.1
RefSeqiWP_015591195.1, NC_021169.1

3D structure databases

ProteinModelPortaliN0BH36
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGK61597; AGK61597; Asulf_01622
GeneIDi15393257
KEGGiast:Asulf_01622

Phylogenomic databases

KOiK04802
OrthoDBiPOG093Z0814

Enzyme and pathway databases

BioCyciASUL387631:G1HH6-1595-MONOMER

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiN0BH36_9EURY
AccessioniPrimary (citable) accession number: N0BH36
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: March 28, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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