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UniProtKB - M9PFV2 (M9PFV2_DROME)
Protein
Submitted name:
Myosin phosphatase targeting subunit 75D, isoform B
Gene
MYPT-75D
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- myosin phosphatase regulator activity Source: FlyBase
- protein phosphatase 1 binding Source: FlyBase
- protein phosphatase regulator activity Source: GO_Central
- protein serine/threonine phosphatase activity Source: UniProtKB-EC
GO - Biological processi
- imaginal disc-derived wing morphogenesis Source: FlyBase
- regulation of protein dephosphorylation Source: GO_Central
Keywordsi
Molecular function | HydrolaseImported |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:MYPT-75DImported Synonyms:Dmel\CG6896Imported, Mypt-75dImported, MYPT75-DImported, MYPT75DImported ORF Names:CG6896Imported, Dmel_CG6896Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0036801, MYPT-75D |
VEuPathDBi | VectorBase:FBgn0036801 |
Expressioni
Gene expression databases
Bgeei | FBgn0036801, Expressed in spermathecum and 39 other tissues |
ExpressionAtlasi | M9PFV2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 151 – 183 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 184 – 216 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 279 – 311 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 312 – 344 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 60 – 85 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 369 – 467 | DisorderedSequence analysisAdd BLAST | 99 | |
Regioni | 560 – 627 | DisorderedSequence analysisAdd BLAST | 68 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 369 – 383 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 396 – 421 | Basic and acidic residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 422 – 464 | Polar residuesSequence analysisAdd BLAST | 43 | |
Compositional biasi | 560 – 591 | Polar residuesSequence analysisAdd BLAST | 32 | |
Compositional biasi | 601 – 627 | Polar residuesSequence analysisAdd BLAST | 27 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000154090 |
HOGENOMi | CLU_000134_54_2_1 |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
M9PFV2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKGILIQRK SQEDASYTKQ LKMEHADLVA EMQTVESLPT HERLQLARLR
60 70 80 90 100
RAQQLKLSRQ KDKEWAKLQR AKGNTASGGS GTGSLGNGLM NGNGDTTHHF
110 120 130 140 150
RHANGSGTLS GRRHISFENS VVLLEAASRN DMPEVAALLQ HGITPDAANE
160 170 180 190 200
DGLTAMHQAC IDNNVEMLQL LLEYGANVDA QDSDKWTPLH AAATCGHLEL
210 220 230 240 250
VRILIRHGAN LLAVNTDGNM PYDLCDDEKT LDFIEGEMAQ RGVTQELIDE
260 270 280 290 300
TRSSTERIML RDLMELARTG GDLEEPDYQC ATPLHIAAAN GYVRVVEFLL
310 320 330 340 350
EQHVNVDAMD KDLWTPVHAA ACWGHLEVLE MLAQCGADLN VRNKDDETPS
360 370 380 390 400
DICEDPEIRE RIEQLKTEQE SKRLAEAQRR RVRRSQSNNT RAQSVRRTSL
410 420 430 440 450
RDKTLTTKKD AVEETRLRLQ AQEATDSEAP SSAGDPLTNG YGYGNNNGEK
460 470 480 490 500
RPSTGSSNGQ PLPHSKSADA LDNATAALSA NATHSYPSRR PPDGRENDEL
510 520 530 540 550
LRLKAAGAAG EMQRATSAAA VILTEKGTAA SAEAVQIQSS KEAANGKINV
560 570 580 590 600
QVTVLVGAGG SSSNNNNNLS TSNNNNNGSA PISTQPTLGH MGAGSVLSDF
610 620 630
EGSSPAGSSL NKFSGITGDV VTDSTSSSRR CCVLM
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ8SY34 | Q8SY34_DROME | LD46604p | MYPT-75D Dmel\CG6896, Mypt-75d, MYPT75-D, MYPT75D, CG6896 | 741 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AGB94710.1 |
RefSeqi | NP_001262017.1, NM_001275088.1 |
Genome annotation databases
EnsemblMetazoai | FBtr0331420; FBpp0303837; FBgn0036801 |
GeneIDi | 40032 |
KEGGi | dme:Dmel_CG6896 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AGB94710.1 |
RefSeqi | NP_001262017.1, NM_001275088.1 |
3D structure databases
SMRi | M9PFV2 |
ModBasei | Search... |
PTM databases
SwissPalmi | M9PFV2 |
Proteomic databases
PRIDEi | M9PFV2 |
Protocols and materials databases
DNASUi | 40032 |
Genome annotation databases
EnsemblMetazoai | FBtr0331420; FBpp0303837; FBgn0036801 |
GeneIDi | 40032 |
KEGGi | dme:Dmel_CG6896 |
Organism-specific databases
CTDi | 40032 |
FlyBasei | FBgn0036801, MYPT-75D |
VEuPathDBi | VectorBase:FBgn0036801 |
Phylogenomic databases
GeneTreei | ENSGT00940000154090 |
HOGENOMi | CLU_000134_54_2_1 |
Miscellaneous databases
BioGRID-ORCSi | 40032, 0 hits in 3 CRISPR screens |
ChiTaRSi | MYPT-75D, fly |
GenomeRNAii | 40032 |
Gene expression databases
Bgeei | FBgn0036801, Expressed in spermathecum and 39 other tissues |
ExpressionAtlasi | M9PFV2, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | M9PFV2_DROME | |
Accessioni | M9PFV2Primary (citable) accession number: M9PFV2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 26, 2013 |
Last sequence update: | June 26, 2013 | |
Last modified: | May 25, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |