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Protein

Palmitoyltransferase

Gene

Hip14

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Hip14Imported
Synonyms:3L1Imported, CG 6017Imported, dHIP14Imported, Dmel\CG6017Imported, hip14Imported, l(3)72AdImported
ORF Names:CG6017Imported, Dmel_CG6017Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0259824 Hip14

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei294 – 314HelicalUniRule annotationAdd BLAST21
Transmembranei320 – 342HelicalUniRule annotationAdd BLAST23
Transmembranei349 – 369HelicalUniRule annotationAdd BLAST21
Transmembranei375 – 394HelicalUniRule annotationAdd BLAST20
Transmembranei474 – 491HelicalUniRule annotationAdd BLAST18
Transmembranei533 – 554HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiM9PFE4
PRIDEiM9PFE4

Expressioni

Gene expression databases

BgeeiFBgn0259824
ExpressionAtlasiM9PFE4 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0303194

Structurei

3D structure databases

ProteinModelPortaliM9PFE4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 251ANK_REP_REGIONInterPro annotationAdd BLAST200
Repeati77 – 109ANKPROSITE-ProRule annotationAdd BLAST33
Repeati111 – 143ANKPROSITE-ProRule annotationAdd BLAST33
Repeati144 – 176ANKPROSITE-ProRule annotationAdd BLAST33
Repeati212 – 245ANKPROSITE-ProRule annotationAdd BLAST34

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509 Eukaryota
COG0666 LUCA
COG5273 LUCA
GeneTreeiENSGT00530000063074
OrthoDBiEOG091G056H

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01529 DHHC, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits

Sequencei

Sequence statusi: Complete.

M9PFE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYQSACQAAT TGSCVPGTGQ QPDNERQSAL IAQQPPTAPV EPDYSGFDIV
60 70 80 90 100
KATQYGAIAR VRELVESGWD VNQPDSETVT LLHWAAINNR RDIIRYFLEK
110 120 130 140 150
GATVDAVGGE LNATPLHWAT RQGHLGAVVL LMAAGADPRI RDAEGCSCIH
160 170 180 190 200
IAAQFAHTAL VAYFIAKGVD PDLQDRGGMT ALMWAAWKVC ALDPVRLLLT
210 220 230 240 250
LGANPAMVDY THGNTALHWA ILARNATAIS TLVLKSKASL DVPNLRGETP
260 270 280 290 300
LSMLESQTGA IWIGAKVMDR VKEAALTSQQ RRSLLSKLRH DKRLRWWSMV
310 320 330 340 350
ACPFTAFYLA GIVFTVNTLY IIKFFLLGCL YSIFHTIGKA LFDEHLMALL
360 370 380 390 400
PLSVYLATKA WFYVTWLMYI DDAVSFTATV CFLISSLLLW VCFLKSWKGD
410 420 430 440 450
PGIIRPTREQ RFKTIIELSE RGGIGFEPAS FCSGCLVRRP IRSKHCSVCD
460 470 480 490 500
RCVARFDHHC PWVGNCIGLK NHSYFMGFLW MLLIMCAWML YGGSKYYVNQ
510 520 530 540 550
CNVRFDDFLG AMRAIGNCDA WVGWVMGNAL LHMSWVILLT ICQTYQVICL
560 570 580 590 600
GMTTNERMNR GRYRHFQAKG GHSPFTRGPI QNLVDFLECS CFGLVQPKRV
610 620 630 640 650
DWMNYYDYDA QTHQTIEKEP LLSVDCPDGM AGDHQYVXDK TYRDAKTLQM

PIAHV
Length:655
Mass (Da):73,379
Last modified:June 26, 2013 - v1
Checksum:i8D0386CA83C509E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AGB94603.1
RefSeqiNP_001261910.1, NM_001274981.1
UniGeneiDm.11460

Genome annotation databases

EnsemblMetazoaiFBtr0330161; FBpp0303194; FBgn0259824
GeneIDi39747

Similar proteinsi

Entry informationi

Entry nameiM9PFE4_DROME
AccessioniPrimary (citable) accession number: M9PFE4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: June 20, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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