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Entry version 46 (03 Jul 2019)
Sequence version 1 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein, isoform E

Gene

CG17233

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform EImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CG17233Imported
Synonyms:CG6918Imported, Dmel\CG17233Imported
ORF Names:CG17233Imported, Dmel_CG17233Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0036958 CG17233

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0036958 Expressed in 30 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
M9NFL3 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
M9NFL3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni480 – 541DisorderedSequence analysisAdd BLAST62
Regioni575 – 609DisorderedSequence analysisAdd BLAST35
Regioni669 – 690DisorderedSequence analysisAdd BLAST22
Regioni728 – 804DisorderedSequence analysisAdd BLAST77
Regioni826 – 874DisorderedSequence analysisAdd BLAST49
Regioni913 – 957DisorderedSequence analysisAdd BLAST45
Regioni975 – 995DisorderedSequence analysisAdd BLAST21

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili171 – 205Sequence analysisAdd BLAST35
Coiled coili221 – 241Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi500 – 541PolarSequence analysisAdd BLAST42
Compositional biasi669 – 689PolarSequence analysisAdd BLAST21
Compositional biasi728 – 757PolarSequence analysisAdd BLAST30
Compositional biasi765 – 795PolarSequence analysisAdd BLAST31
Compositional biasi859 – 874PolarSequence analysisAdd BLAST16
Compositional biasi921 – 957PolarSequence analysisAdd BLAST37

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ISH8 Eukaryota
ENOG410Y937 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000004986

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

M9NFL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPNSSPWSY AYNRIVPASA GSSGGTAEDF QHPHLATITA ASIASFNAAA
60 70 80 90 100
ASGGSFVPPS PIGSYNPVFQ QIYHHAAAAS VQPKPAHYAS SAVSTPHRQL
110 120 130 140 150
QLPSSLDKQL SSFQNQAAVS AAAAAVVNNV ASNYYGENSS SSGASPSPTT
160 170 180 190 200
VALTSTSLTW NTPNMISNTF LAMQQQQAQQ QQQQAQQQQQ QAQQQQQQAQ
210 220 230 240 250
QQQLNLVADK VQQQQQQTAA QQQQQQLHQQ LQQEIAEADT EPDTYYTIDG
260 270 280 290 300
RKVKVTRKDG QPYRATIVDQ QDASPVPLAV PVPAGSYPVQ YASPALSSAD
310 320 330 340 350
GSPITNLHAV DVVSTPQAQV IVYKTASPVQ RRQEAGAGSS AAATPTTVAY
360 370 380 390 400
SSVIQSTLQQ QQQQQNLCWT KLEDNGAGQE DIKNVLQLQV KQEHRQLDFA
410 420 430 440 450
SEASSVDAGG GGENLVFNLP PGLEIKQTFY PASVVDGEQL QLQEHNQNQS
460 470 480 490 500
QSSGRRQHVV ANMIMSPSAG NLASQIQVVP KEEVKPPPKP AKTPRKRQPK
510 520 530 540 550
KTLIPSSSDY GNVRSPQEPQ HHQLQQQQQQ QQQHNQQQQQ QNTYYDFNSK
560 570 580 590 600
WNAPLKTENN AASVSPAATI NIPTYPQQSQ QQQHQQQQAQ QQQQQHLPQP
610 620 630 640 650
AHLQSSQAQS HLTQLAQYYP AFPQPIASQY TACMQQQQQQ QQQQQQQQQQ
660 670 680 690 700
QAAYTQQQHQ QAYTQQQQQQ AQQQRQEKSE ATQQQEEEAN AAAAAAAAAA
710 720 730 740 750
ASNKVIVPNI EEELDFLADA TATPKQGYAN SLSSNGRGTN SSTNNTNFGI
760 770 780 790 800
RNPNKTPSPE PTNCPPNSHA SNNGHGHSAV TPVAPSSTGA SASTAYSPVA
810 820 830 840 850
PKPVSVGTLI GEKKTQFMDS YLKFLQGERD DDPPPVVKPS RKLNYPRAPY
860 870 880 890 900
KRKGKGSGSG DEPTTSQATQ SAGDAVQAVD GLAGLVGDDG HRIKILSQTQ
910 920 930 940 950
ILPKKRPHAQ MVAAAAAAES APSSSVIQQP GDQTSFRPYA QQQQQAQQQQ
960 970 980 990 1000
QQSMSGQHFV QQHCAQLTAG AGQASANATA NSNSTTPTPA PAPNPHHFIN

LLWPWQH
Length:1,007
Mass (Da):108,790
Last modified:June 26, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3A4DA5548BF257FF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VWA0Q9VWA0_DROME
Uncharacterized protein, isoform C
CG17233 CG6918, Dmel\CG17233, CG17233, Dmel_CG17233
1,465Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8IQV6Q8IQV6_DROME
Uncharacterized protein, isoform A
CG17233 CG6918, Dmel\CG17233, CG17233, Dmel_CG17233
1,173Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NEF4M9NEF4_DROME
Uncharacterized protein, isoform G
CG17233 CG6918, Dmel\CG17233, CG17233, Dmel_CG17233
1,443Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NDW6M9NDW6_DROME
Uncharacterized protein, isoform F
CG17233 CG6918, Dmel\CG17233, CG17233, Dmel_CG17233
1,464Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NG75M9NG75_DROME
Uncharacterized protein, isoform H
CG17233 CG6918, Dmel\CG17233, CG17233, Dmel_CG17233
1,006Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8IQV5Q8IQV5_DROME
LD13191p
CG6918 Dmel\CG17233, CG17233, Dmel_CG17233
772Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AFH04510.1

NCBI Reference Sequences

More...
RefSeqi
NP_001246839.1, NM_001259910.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0306326; FBpp0297422; FBgn0036958

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
40220

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG17233

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AFH04510.1
RefSeqiNP_001246839.1, NM_001259910.2

3D structure databases

SMRiM9NFL3
ModBaseiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0306326; FBpp0297422; FBgn0036958
GeneIDi40220
KEGGidme:Dmel_CG17233

Organism-specific databases

FlyBaseiFBgn0036958 CG17233

Phylogenomic databases

eggNOGiENOG410ISH8 Eukaryota
ENOG410Y937 LUCA
GeneTreeiENSGT00390000004986

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CG17233 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
40220

Gene expression databases

BgeeiFBgn0036958 Expressed in 30 organ(s), highest expression level in embryo
ExpressionAtlasiM9NFL3 baseline and differential

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM9NFL3_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M9NFL3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: July 3, 2019
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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