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Entry version 59 (11 Dec 2019)
Sequence version 1 (26 Jun 2013)
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Protein
Submitted name:

Ca[2+]-channel protein alpha[[1]] subunit T, isoform E

Gene

Ca-alpha1T

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ca[2+]-channel protein alpha[[1]] subunit T, isoform EImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ca-alpha1TImported
Synonyms:alpha1TImported, Ca-alphaT-RCImported, Ca1GImported, Caalpha1TImported, catImported, CG12544Imported, CG4222Imported, DmalphaGImported, Dmca1GImported, Dmel\CG15899Imported, T-type Ca[2+]Imported
ORF Names:CG15899Imported, Dmel_CG15899Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0264386 Ca-alpha1T

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei430 – 453HelicalSequence analysisAdd BLAST24
Transmembranei552 – 570HelicalSequence analysisAdd BLAST19
Transmembranei590 – 615HelicalSequence analysisAdd BLAST26
Transmembranei1227 – 1245HelicalSequence analysisAdd BLAST19
Transmembranei1257 – 1278HelicalSequence analysisAdd BLAST22
Transmembranei1290 – 1310HelicalSequence analysisAdd BLAST21
Transmembranei1356 – 1378HelicalSequence analysisAdd BLAST23
Transmembranei1448 – 1472HelicalSequence analysisAdd BLAST25
Transmembranei2196 – 2217HelicalSequence analysisAdd BLAST22
Transmembranei2293 – 2315HelicalSequence analysisAdd BLAST23
Transmembranei2396 – 2419HelicalSequence analysisAdd BLAST24
Transmembranei2476 – 2497HelicalSequence analysisAdd BLAST22
Transmembranei2509 – 2533HelicalSequence analysisAdd BLAST25
Transmembranei2612 – 2632HelicalSequence analysisAdd BLAST21
Transmembranei2697 – 2723HelicalSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0264386 Expressed in 10 organ(s), highest expression level in head

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
M9NDQ0 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini300 – 622Ion_transInterPro annotationAdd BLAST323
Domaini1225 – 1481Ion_transInterPro annotationAdd BLAST257
Domaini2157 – 2429Ion_transInterPro annotationAdd BLAST273
Domaini2475 – 2732Ion_transInterPro annotationAdd BLAST258

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 272DisorderedSequence analysisAdd BLAST272
Regioni728 – 762DisorderedSequence analysisAdd BLAST35
Regioni788 – 856DisorderedSequence analysisAdd BLAST69
Regioni953 – 979DisorderedSequence analysisAdd BLAST27
Regioni1121 – 1165DisorderedSequence analysisAdd BLAST45
Regioni1503 – 1523DisorderedSequence analysisAdd BLAST21
Regioni1572 – 1699DisorderedSequence analysisAdd BLAST128
Regioni1792 – 1929DisorderedSequence analysisAdd BLAST138
Regioni2070 – 2106DisorderedSequence analysisAdd BLAST37
Regioni3067 – 3087DisorderedSequence analysisAdd BLAST21
Regioni3157 – 3200DisorderedSequence analysisAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili616 – 636Sequence analysisAdd BLAST21
Coiled coili1477 – 1497Sequence analysisAdd BLAST21
Coiled coili2042 – 2069Sequence analysisAdd BLAST28
Coiled coili2428 – 2448Sequence analysisAdd BLAST21
Coiled coili2723 – 2746Sequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi8 – 33PolarSequence analysisAdd BLAST26
Compositional biasi50 – 82PolarSequence analysisAdd BLAST33
Compositional biasi113 – 153PolarSequence analysisAdd BLAST41
Compositional biasi155 – 200PolyampholyteSequence analysisAdd BLAST46
Compositional biasi230 – 270PolarSequence analysisAdd BLAST41
Compositional biasi788 – 845PolarSequence analysisAdd BLAST58
Compositional biasi1136 – 1161PolarSequence analysisAdd BLAST26
Compositional biasi1572 – 1586PolarSequence analysisAdd BLAST15
Compositional biasi1589 – 1653PolyampholyteSequence analysisAdd BLAST65
Compositional biasi1663 – 1681PolarSequence analysisAdd BLAST19
Compositional biasi1816 – 1839PolarSequence analysisAdd BLAST24
Compositional biasi1875 – 1890PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1894 – 1929PolarSequence analysisAdd BLAST36
Compositional biasi2070 – 2102PolarSequence analysisAdd BLAST33
Compositional biasi3157 – 3189PolyampholyteSequence analysisAdd BLAST33

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2302 Eukaryota
ENOG410XNP6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000168093

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821 Ion_trans_dom
IPR005445 VDCC_T_a1
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520 Ion_trans, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01629 TVDCCALPHA1

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

M9NDQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPQPAAAVA TATTTTTQSA TSATSTAATS AAAAAARNGQ RRRVAAATEG
60 70 80 90 100
CNSNIGNSNS KLSSNTTTNT TKRVSQMHSN EEPPMTVIVD GGGGSNVSVS
110 120 130 140 150
GGSSHRRGSQ RLRKTSSSSA NAKSASANPT ERTSSGQRSS HRQTSNASDG
160 170 180 190 200
GGSSRRRYQG KEHHDRRDRQ DRQDRQDRQE RSDRHERRDR RDEQQAARRR
210 220 230 240 250
TGRRHSGASS LSDAAAATAA GRSRSRGGGR TGGAVSSSTG SSCNGSCSSD
260 270 280 290 300
DGDSSHTSSS SSSSSSGEPN LPYPGFPEIS IRALTQYTRP RNWCLMLITN
310 320 330 340 350
PWFERVSILV ILLNCITLGM YQPCVDDACV TNRCKILQIF DDIIFAFFAL
360 370 380 390 400
EMTIKMVAMG ICGKNTYLAD SWNRLDFFIV LAGLLEYVMH VENLNLTAIR
410 420 430 440 450
TIRVLRPLRA INRIPSMRIL VMLLLDTLPM LGNVLLLCFF VFFIFGIIGV
460 470 480 490 500
QLWEGILRQR CSLMRTEGMV YPLTLSQYYE FSKDQDYICS TPNDSGMHLC
510 520 530 540 550
GNFPPYRIGS LVCNEEAKLF DFNEPTNTSC VNWNQYYTTC KQSGENPFQG
560 570 580 590 600
TISFDNIGMA WVAIFLVISL EGWTDIMYYV QDAHSFWDWI YFVLLIVIGS
610 620 630 640 650
FFMINLCLVV IATQFSETKK REMERMRQER ARYTSTSTLA SSTNNSEPAT
660 670 680 690 700
CYAEIVKYIA HLWRRFKRRM LKKYQRQQRK EGLLPNADNL TFSPSRIKCH
710 720 730 740 750
HPKCPKYSNR KPSSIQDQMI TVMVPLNSAS NNINNNNNNN SNSSNHNGSG
760 770 780 790 800
NHTAAGGGNN NNNNNNNNAA SCTTVALVNG INGSAASVTM SSAHHQQHQL
810 820 830 840 850
LQHQQQQHQN QQQQQQQQQH SSSDNTEQSL APDGLPRSSS LKKSTAHHQL
860 870 880 890 900
KPEGSAAEQK TILLKFPQQM IDSEQLILQL GNLGKSHPCT SGFLSPPTSA
910 920 930 940 950
SRRPSVMFNE YVLLHTPPAL NADPATAGTT TTVAPTVATV AGTAAAAAAA
960 970 980 990 1000
AATGSGSGNN NHQNGGASGG AGTGGTTEKS NIFSTEKMTQ AGDGSIWQVN
1010 1020 1030 1040 1050
LPQTIGTIAN PYADCSELGI HDAMTCQELL AFSVAFSAAL PTGQSTLESF
1060 1070 1080 1090 1100
YTSLARCDPH TAEALRAHHK PRSVPTGQNQ TTPGAEGATV MVASTAGDTG
1110 1120 1130 1140 1150
QTLQPSTVSA VVGGTIDSHA ANHRRKEHHQ QSHHHHNNNN TTSHSRNYRS
1160 1170 1180 1190 1200
RQGQGNSRMR EPRAPTGNYM EDYACCYDLY QNALSPLDER PRQRSPTTRC
1210 1220 1230 1240 1250
LISVYRCMSR VCSWIRRYIR RLVEHKYFQQ GILLAILINT LSMGIEYHNQ
1260 1270 1280 1290 1300
PPELTAIVET SNVVFSGIFA VEMLLKVVAE GPFRYIANGF NVFDGIIVIL
1310 1320 1330 1340 1350
SAIEICQTFM GNGTGGGGSG LSVLRTFRLL RILKLVRFMP NLRRQLFVML
1360 1370 1380 1390 1400
RTMDNVAVFF SLLVLFIFIF SILGMYLFGG KFCKFLDESG LERECTCPEI
1410 1420 1430 1440 1450
ISRHPQCECD RKHFNNILWA TVTVFQILTQ EDWNVVLFNG MEKTSHWAAL
1460 1470 1480 1490 1500
YFVALMTFGN YVLFNLLVAI LVEGFSSERN ERREREQREL VKKLREETLA
1510 1520 1530 1540 1550
ENYSDGMYDE SRSEADSSTT NDSYYEVRNR WRSAEDVRKL QDSVELIIEA
1560 1570 1580 1590 1600
KSNMHRQRLL QPTHDYQINE LPASSAAPSA SGTSGASAPG DRERDRDRDR
1610 1620 1630 1640 1650
DRERDRDRDR ERDREAGGGG KEEGAQHAKP RGGLKKTYSI KERRSEAPRL
1660 1670 1680 1690 1700
SKIRLARDPP IITTTAATPQ DSPSTTLEPG MSFRQWGDME PPSPPSPSLL
1710 1720 1730 1740 1750
RPPNIFTGGQ RSLDEGIPSI DLIPPSPVLS HKPLNILNAS QLGVGMGGGV
1760 1770 1780 1790 1800
PSTAGSSSSM HSVIIDDISK SSSSTAAATP IYVPTISSTA DAQSQSHSLN
1810 1820 1830 1840 1850
DVSVGSSPGG EIPATGMSRN ANTGASTSGS SSSERLPLAP PPQQGSFKQR
1860 1870 1880 1890 1900
LRRGSSKKRR ASALALATDD NPARRTLDNQ ARRTQDEEEE QQQLNNGGDN
1910 1920 1930 1940 1950
SCLLRNSNAV VSGSSSGTKE TNRLSPQNSI RRLSNTLSIG SGPVGSRRAS
1960 1970 1980 1990 2000
ACIFNSQVYQ NLNQPPKLRP GSGQRRMSSI ELAFSKTSHL NLHNLEANRK
2010 2020 2030 2040 2050
SLSYTNSKMD LDKWNKSYGN LNEPDNMLQQ YMEARDKRKN SISHYNLKKR
2060 2070 2080 2090 2100
LEEKELQQLQ QLHQQQLLQQ RQDSFSSTTQ QQQQQLQQHR LSKDQQQLAM
2110 2120 2130 2140 2150
QPHSMVPGGG ERYSKLKMLI EQLTPKHFTT EREDYSLYIF PEDNRFRQIC
2160 2170 2180 2190 2200
TWFVNQKWFD NVVLLFIALN CITLAMERPN IPPSSTERLF LATANYVFTV
2210 2220 2230 2240 2250
VFTVEMFIKV VATGMFYGHD AYFTSGWNIM DGSLVTISII DLLMSLISES
2260 2270 2280 2290 2300
SPRIFGILRV FRLLRSLRPL RVINRAPGLK LVVQTLLSSL RPIGNIVLIC
2310 2320 2330 2340 2350
CTFFIIFGIL GVQLFKGTFY YCEGENIKGV RNADECRRIP GNVWTNRKYN
2360 2370 2380 2390 2400
FDDLGKALMS LFVLSSRDGW VNIMYTGLDA VGVDQQPIVN YNEWRLLYFI
2410 2420 2430 2440 2450
AFILLVGFFV LNMFVGVVVE NFHRCREEQE KEEKIRRAAK RALQMEKKRR
2460 2470 2480 2490 2500
RMHEPPYYTN YSPTRMFVHN VVTSKYFDLA IAAVIGLNVV TMAMEYYKMP
2510 2520 2530 2540 2550
SGLKYALKIF NYFFTAVFIL EANMKLVALG WKLYLKDRWN QLDVGIVLLS
2560 2570 2580 2590 2600
IVGIVLEELE TNTHQIIPIN PTIIRVMRVL RIARVLKLLK MANGIRALLD
2610 2620 2630 2640 2650
TVMQALPQVG NLGLLFFLLF FIFAALGVEL FGRLECSDEI PCQGLGEHAH
2660 2670 2680 2690 2700
FANFGMAFLT LFRVATGDNW NGIMKDTLRD NCDDAADCVR NCCVSSVIAP
2710 2720 2730 2740 2750
IFFVIFVLMA QFVLVNVVVA VLMKHLEESH KQMEDELDME VELERELVRE
2760 2770 2780 2790 2800
QEFAQEQKLC QQLAEAQSKA AAPPRPLAKV KSLPKNFIYS TPSLDKKFPA
2810 2820 2830 2840 2850
VSGVNNPSLT SSAATNLNQV ATAGSGGAAP GAVPAGSGAG PRRQTVQYFQ
2860 2870 2880 2890 2900
QPPQSMLGGL SLAEMGGTLT PQALGARLGE PFGGGGGNKS GPRRQSYWQI
2910 2920 2930 2940 2950
NPIRKRGVLS KERSLDEQAI RRRNLEAKRT SCDSLPWGGD ALDCRRGTIF
2960 2970 2980 2990 3000
ESLESDGGGV GGGGSGGGGG GLGGGVSYDL RSVRSADVGH SEMDGDVSLS
3010 3020 3030 3040 3050
VVSALVPSVT TPLPPPLSLP IVTPTSTPTP LQLPMPMPMP MAHPPPRRPF
3060 3070 3080 3090 3100
GWSQSVDQGC LRSNLLLSVP RSMPPRSRSG STKQLFKQQA LDEDADMDEN
3110 3120 3130 3140 3150
SLLLPTAAGG GSGPGSVAVI ASSSLDLPDQ SGSSKQILPD IALGVSKSDS
3160 3170 3180 3190 3200
SDILRIISER RRMDQREQRE PEQDQDNEAE DRDSDYKELL LVKSPQSSMD
Length:3,200
Mass (Da):353,483
Last modified:June 26, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0611475C73BD6069
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PGH9M9PGH9_DROME
Ca[2+]-channel protein alpha[[1]] s...
Ca-alpha1T alpha1T, Ca-alphaT-RC, Ca1G, Caalpha1T, cat
3,218Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8JUY8A8JUY8_DROME
Ca[2+]-channel protein alpha[[1]] s...
Ca-alpha1T alpha1T, Ca-alphaT-RC, Ca1G, Caalpha1T, cat
3,205Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9W433Q9W433_DROME
Ca[2+]-channel protein alpha[[1]] s...
Ca-alpha1T alpha1T, Ca-alphaT-RC, Ca1G, Caalpha1T, cat
3,188Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9NGR9M9NGR9_DROME
Ca[2+]-channel protein alpha[[1]] s...
Ca-alpha1T alpha1T, Ca-alphaT-RC, Ca1G, Caalpha1T, cat
3,180Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AFH07259.1

NCBI Reference Sequences

More...
RefSeqi
NP_001245545.1, NM_001258616.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0304610; FBpp0293152; FBgn0264386

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31550

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AFH07259.1
RefSeqiNP_001245545.1, NM_001258616.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiFBtr0304610; FBpp0293152; FBgn0264386
GeneIDi31550

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
31550
FlyBaseiFBgn0264386 Ca-alpha1T

Phylogenomic databases

eggNOGiKOG2302 Eukaryota
ENOG410XNP6 LUCA
GeneTreeiENSGT00940000168093

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
31550

Gene expression databases

BgeeiFBgn0264386 Expressed in 10 organ(s), highest expression level in head
ExpressionAtlasiM9NDQ0 baseline and differential

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR005445 VDCC_T_a1
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 4 hits
PRINTSiPR01629 TVDCCALPHA1

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM9NDQ0_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M9NDQ0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: December 11, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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