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Entry version 62 (19 Jan 2022)
Sequence version 1 (26 Jun 2013)
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Protein

RNA helicase

Gene

armi

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseARBA annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA helicaseARBA annotation (EC:3.6.4.13ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:armiImported
Synonyms:APC16Imported, ARMIImported, ArmiImported, Dmel\CG11513Imported
ORF Names:CG11513Imported, Dmel_CG11513Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0041164, armi

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0041164

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0041164, Expressed in female gonad and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
M9NDG7, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
M9NDG7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini664 – 748AAA_11InterPro annotationAdd BLAST85
Domaini791 – 867AAA_11InterPro annotationAdd BLAST77
Domaini900 – 1098AAA_12InterPro annotationAdd BLAST199

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.ARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000165903

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001666_3_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
YCATVDI

Family and domain databases

Conserved Domains Database

More...
CDDi
cd18808, SF1_C_Upf1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.300, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR045055, DNA2/NAM7-like
IPR041679, DNA2/NAM7-like_C
IPR041677, DNA2/NAM7_AAA_11
IPR026122, MOV-10
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10887, PTHR10887, 1 hit
PTHR10887:SF419, PTHR10887:SF419, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13086, AAA_11, 2 hits
PF13087, AAA_12, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

M9NDG7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEKMDQQLK ANPNEINGVL SNKIAELTHG LSEMDVSKES SCTARKGVIT
60 70 80 90 100
SLDGDRGVID KDVLFETKVA EDIILDLHVG CVVEYLTFTT GEAMRVVKVK
110 120 130 140 150
SILEHSWEDT SQKEIEKAVD NLKNEKPTFF NTETRSVLGL ISQRLASSID
160 170 180 190 200
VETEYGQLTV ELDNIEMNFI PTNGDRVRLE CNIQLDDGFV DKQGEILEVT
210 220 230 240 250
KLFPTRIQEG EKCIVERVYV HMVVLGPETY ILKTDLPTGT DLHLGDIVLA
260 270 280 290 300
DLIECQYSKF TRRAIKITPL EKNFGATKLT QQSSMGSSGS GKAVTVTGVN
310 320 330 340 350
RFITAELWQK ESVSLKLTNN LNRTLRLESI TVCNDSESQL SVVSPLESKE
360 370 380 390 400
ISSGSEITVT FEIHTQFLGE AIEKYVLNFD LLKVRRVFTV IVCKTKEEVA
410 420 430 440 450
EAEKRMIAAE ALMAPGRNSQ ERSRFYANQV WCNKVDVIPG QQIVTKRRFV
460 470 480 490 500
ALRLGCFEVP KELRQICLTS ERRQEMIKAI EQHYSFLTEP LSIKTYMHRF
510 520 530 540 550
RLLLHLEEIE CFVNFRNYDR DRAHFLRDGE FLTLQIENLA ERRPSLVIGD
560 570 580 590 600
TLRVINPWSD PDSQTTKSYE GIIHKVLFDR ILLKFHSSFQ EKYNGEDYRL
610 620 630 640 650
EFYFSRYSFR KQHHAISKIV GVMGEDFLFP SKVTKRENPQ LDVYMKDDDM
660 670 680 690 700
YLYDSKLEWY NQSLNSIQKR AVFNILRGEA ENIPYVLFGP PGSGKTMTLI
710 720 730 740 750
ETLLQLVRNL PGARILVGTP SNSSADLVTK RLIDSKALLQ GDFIRLVSYN
760 770 780 790 800
QVEKDLIPPE IMSYCATSDV GAVGSCEDKM MVTESGLKLR CQAKFIGTHR
810 820 830 840 850
ITISTCTTLG NFLQLGFPAG HFTHVLFDEA GQCTEPETMV PIVMLTKKRS
860 870 880 890 900
QVVLSGDPRQ LQSIVTSRIA SKMGFSISFL ERLLERSPYR KDLQRFPESS
910 920 930 940 950
GYNPLVLTKL LYNYRALPSI MSIYSRLFYD DELIPVLSEK DSRESRLLSK
960 970 980 990 1000
LRCVFESEKD IPQAHGTFFY GIIGENRQNN DSPSWFNPQE VREVFLMTIA
1010 1020 1030 1040 1050
LYRANVTADQ IGIITPYQKQ VKMLRSMFIG TDVVMPKIGS VEEFQGQERD
1060 1070 1080 1090 1100
IILISTVRSS EEILRMDARF SLGFVRCSKR LNVAVSRARA MMIIFGNPHL
1110 1120 1130 1140 1150
LAVDECWRQL ILFCVKNNAY FGCDLPQMVI NQKDEVPVCL ETFVPSLNTT

DDLN
Length:1,154
Mass (Da):131,506
Last modified:June 26, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC7FBA7068BCC8F31
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6J5K9ARMI_DROME
Probable RNA helicase armi
armi CG11513
1,188Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AFH04274.1

NCBI Reference Sequences

More...
RefSeqi
NP_001246603.1, NM_001259674.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0309840; FBpp0301574; FBgn0041164

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
38427

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AFH04274.1
RefSeqiNP_001246603.1, NM_001259674.1

3D structure databases

SMRiM9NDG7
ModBaseiSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0309840; FBpp0301574; FBgn0041164
GeneIDi38427

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
38427
FlyBaseiFBgn0041164, armi
VEuPathDBiVectorBase:FBgn0041164

Phylogenomic databases

GeneTreeiENSGT00940000165903
HOGENOMiCLU_001666_3_0_1
OMAiYCATVDI

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
38427, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
38427

Gene expression databases

BgeeiFBgn0041164, Expressed in female gonad and 33 other tissues
ExpressionAtlasiM9NDG7, baseline and differential

Family and domain databases

CDDicd18808, SF1_C_Upf1, 1 hit
Gene3Di3.40.50.300, 3 hits
InterProiView protein in InterPro
IPR045055, DNA2/NAM7-like
IPR041679, DNA2/NAM7-like_C
IPR041677, DNA2/NAM7_AAA_11
IPR026122, MOV-10
IPR027417, P-loop_NTPase
PANTHERiPTHR10887, PTHR10887, 1 hit
PTHR10887:SF419, PTHR10887:SF419, 1 hit
PfamiView protein in Pfam
PF13086, AAA_11, 2 hits
PF13087, AAA_12, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM9NDG7_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M9NDG7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: January 19, 2022
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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