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Protein
Submitted name:

Receptor-type tyrosine-protein phosphatase C

Gene

PTPRC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor-type tyrosine-protein phosphatase CImported
Gene namesi
Name:PTPRCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000081237.18
HGNCiHGNC:9666 PTPRC

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000081237

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500410111426 – 118Sequence analysisAdd BLAST93

Proteomic databases

PeptideAtlasiM9MML3

Expressioni

Gene expression databases

BgeeiENSG00000081237 Expressed in 219 organ(s), highest expression level in blood
ExpressionAtlasiM9MML3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM9MML3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 32PTP_NInterPro annotationAdd BLAST26

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900

Family and domain databases

InterProiView protein in InterPro
IPR024739 PTP_recept_N
PfamiView protein in Pfam
PF12453 PTP_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

M9MML3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTMYLWLKLL AFGFAFLDTE VFVTGQSPTP SPTGLTTAKM PSVPLSSDPL
60 70 80 90 100
PTHTTAFSPA STFERENDFS ETTTSLSPDN TSTQVSPDSL DNASAFNTTG
110
VSSVQTPHLP THADSQTP
Length:118
Mass (Da):12,556
Last modified:May 29, 2013 - v1
Checksum:i70A2EC9D0904D9F3
GO

Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P08575PTPRC_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC CD45
1,306Annotation score:
M3ZCP1M3ZCP1_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
735Annotation score:
A0A075B788A0A075B788_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
753Annotation score:
E9PKH0E9PKH0_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
600Annotation score:
M9MMK9M9MMK9_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
148Annotation score:
A0A0G2JNW2A0A0G2JNW2_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
523Annotation score:
A0A140TA68A0A140TA68_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
505Annotation score:
A0A140TA77A0A140TA77_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
457Annotation score:
A0A140TA57A0A140TA57_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
146Annotation score:
A0A2R8YE81A0A2R8YE81_HUMAN
Receptor-type tyrosine-protein phos...
PTPRC
161Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei118Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157402 Genomic DNA No translation available.
AL355988 Genomic DNA No translation available.
KF510707 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000418674; ENSP00000393360; ENSG00000081237
UCSCiuc057oeq.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157402 Genomic DNA No translation available.
AL355988 Genomic DNA No translation available.
KF510707 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM9MML3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM9MML3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000418674; ENSP00000393360; ENSG00000081237
UCSCiuc057oeq.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000081237.18
HGNCiHGNC:9666 PTPRC
OpenTargetsiENSG00000081237
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900

Miscellaneous databases

ChiTaRSiPTPRC human

Gene expression databases

BgeeiENSG00000081237 Expressed in 219 organ(s), highest expression level in blood
ExpressionAtlasiM9MML3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR024739 PTP_recept_N
PfamiView protein in Pfam
PF12453 PTP_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM9MML3_HUMAN
AccessioniPrimary (citable) accession number: M9MML3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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