UniProtKB - M6BEJ2 (M6BEJ2_LEPBO)
Protein
60 kDa chaperonin
Gene
groL
Organism
Leptospira borgpetersenii serovar Hardjo-bovis str. Sponselee
Status
Functioni
Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation
Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- unfolded protein binding Source: UniProtKB-UniRule
GO - Biological processi
- protein refolding Source: UniProtKB-UniRule
Keywordsi
Molecular function | ChaperoneUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 60 kDa chaperoninUniRule annotationAlternative name(s): GroEL proteinUniRule annotation Protein Cpn60UniRule annotation |
Gene namesi | Name:groLUniRule annotationImported Synonyms:groELUniRule annotation ORF Names:LEP1GSC016_2201Imported |
Organismi | Leptospira borgpetersenii serovar Hardjo-bovis str. SponseleeImported |
Taxonomic identifieri | 1303729 [NCBI] |
Taxonomic lineagei | Bacteria › Spirochaetes › Leptospirales › Leptospiraceae › Leptospira › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Oligomer of 14 subunits composed of two stacked rings of 7 subunits.
UniRule annotationGO - Molecular functioni
- unfolded protein binding Source: UniProtKB-UniRule
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 522 – 546 | DisorderedSequence analysisAdd BLAST | 25 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 345 – 365 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
CDDi | cd03344, GroEL, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
HAMAPi | MF_00600, CH60, 1 hit |
InterProi | View protein in InterPro IPR018370, Chaperonin_Cpn60_CS IPR001844, Chaprnin_Cpn60 IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00298, CHAPERONIN60 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02348, GroEL, 1 hit |
PROSITEi | View protein in PROSITE PS00296, CHAPERONINS_CPN60, 1 hit |
i Sequence
Sequence statusi: Complete.
M6BEJ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKDIEYNET ARRKLLEGVN KLANAVKVTL GPKGRNVVID KKFGAPTITK
60 70 80 90 100
DGVTVAKEIE LEDALENMGA QMVKEVSTKT NDVAGDGTTT ATILAQSIIN
110 120 130 140 150
EGLKNVTAGA NPMSLKRGID KAVTAAVESI RKRAVKIENK KDIANVASIS
160 170 180 190 200
ANNDDTIGNL IADAMDKVGK DGVITVEEAK SIETTLDVVE GMQFDRGYIS
210 220 230 240 250
PYMVTDAESM VATLSDPYIL IYDKKISSMK DLIHILEKVA QAGKPLVIIS
260 270 280 290 300
EEVEGEALAT IVVNTLRKTI SCVAVKAPGF GDRRKAMLED IAILTGGQVI
310 320 330 340 350
SEDLGMKLEN TTLQMLGRAN KVTVDKENTT IIEGKGQTKE IQGRIGQIKK
360 370 380 390 400
QIEDTTSEYD KEKLQERLAK LAGGVAVIHV GAATEVEMKE KKARVEDALS
410 420 430 440 450
ATRAAVEEGI VPGGGLTLLK AQEAVAALKL EGDEATGAKI IFRSLEEPIR
460 470 480 490 500
MITNNAGLEG SVIVEHAKTK KGNEGFNALS MVWEDLVSAG VVDPAKVVRS
510 520 530 540
ALQNAASIGS MILTTEVTIT DKPEKDAPNP MAGMGGGGMG GMGGMM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | ANMU01000170 Genomic DNA Translation: EMJ77929.1 |
RefSeqi | WP_002730932.1, NZ_AQCK01000119.1 |
Genome annotation databases
EnsemblBacteriai | EMJ77929; EMJ77929; LEP1GSC016_2201 |
PATRICi | fig|1218567.3.peg.4102 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | ANMU01000170 Genomic DNA Translation: EMJ77929.1 |
RefSeqi | WP_002730932.1, NZ_AQCK01000119.1 |
3D structure databases
SMRi | M6BEJ2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | EMJ77929; EMJ77929; LEP1GSC016_2201 |
PATRICi | fig|1218567.3.peg.4102 |
Family and domain databases
CDDi | cd03344, GroEL, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
HAMAPi | MF_00600, CH60, 1 hit |
InterProi | View protein in InterPro IPR018370, Chaperonin_Cpn60_CS IPR001844, Chaprnin_Cpn60 IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00298, CHAPERONIN60 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02348, GroEL, 1 hit |
PROSITEi | View protein in PROSITE PS00296, CHAPERONINS_CPN60, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M6BEJ2_LEPBO | |
Accessioni | M6BEJ2Primary (citable) accession number: M6BEJ2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 29, 2013 |
Last sequence update: | May 29, 2013 | |
Last modified: | February 10, 2021 | |
This is version 35 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |