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Protein

L-lactate dehydrogenase

Gene

lldD

Organism
Stenotrophomonas maltophilia RA8
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

(S)-lactate + an oxidized electron acceptor = pyruvate + a reduced electron acceptor.UniRule annotationSAAS annotation

Cofactori

FMNUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei58SubstrateUniRule annotation1
Binding sitei140FMNUniRule annotation1
Binding sitei161FMNUniRule annotation1
Binding sitei163SubstrateUniRule annotation1
Binding sitei189FMNUniRule annotation1
Binding sitei198SubstrateUniRule annotation1
Binding sitei285FMNUniRule annotation1
Active sitei309Proton acceptorUniRule annotation1
Binding sitei312SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi340 – 364FMNUniRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
LigandFlavoprotein, FMNUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
L-lactate dehydrogenaseUniRule annotationSAAS annotation (EC:1.1.-.-UniRule annotationSAAS annotation)
Gene namesi
Name:lldDUniRule annotationImported
ORF Names:SMRA8_2776Imported
OrganismiStenotrophomonas maltophilia RA8Imported
Taxonomic identifieri1118157 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeStenotrophomonasStenotrophomonas maltophilia group
Proteomesi
  • UP000012177 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell inner membrane SAAS annotation; Peripheral membrane protein SAAS annotation
  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneSAAS annotation, Cell membrane, Membrane

Structurei

3D structure databases

ProteinModelPortaliM5CZY6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 413FMN hydroxy acid dehydrogenaseInterPro annotationAdd BLAST382

Sequence similaritiesi

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiPOG091H00L7

Family and domain databases

CDDicd02809 alpha_hydroxyacid_oxid_FMN, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_01559 L_lact_dehydr, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR012133 Alpha-hydoxy_acid_DH_FMN
IPR000262 FMN-dep_DH
IPR037396 FMN_HAD
IPR008259 FMN_hydac_DH_AS
IPR020920 LldD
PfamiView protein in Pfam
PF01070 FMN_dh, 1 hit
PIRSFiPIRSF000138 Al-hdrx_acd_dh, 1 hit
PROSITEiView protein in PROSITE
PS00557 FMN_HYDROXY_ACID_DH_1, 1 hit
PS51349 FMN_HYDROXY_ACID_DH_2, 1 hit

Sequencei

Sequence statusi: Complete.

M5CZY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTSSSCTPR CAPSMTTKPG VRGPRVYLPH TVDPMIISAS TDYRAAAQRR
60 70 80 90 100
LPPFLFHYID GGAYAEHTLK RNVSDLSDIA LRQRVLRNMS DLSLETELFG
110 120 130 140 150
ETLAMPVALA PVGLTGMYAR RGEVQAARAA DSRGIPFTLS TVSVCPIEEV
160 170 180 190 200
APAIQRPMWF QLYVLRDRGF MRNALERAQA AGVTTLVFTV DMPVPGARYR
210 220 230 240 250
DAHSGMSGPN ASLRRIGQAI THPHWAWDVG LFGRPHDLGN ISTYRGNPTG
260 270 280 290 300
LEDYIGWLGS NFDPSISWKD LEWIREFWKG PMVIKGILDP DDARDAVKFG
310 320 330 340 350
ADGIVVSNHG GRQLDGVLST ARALPAIADA VQGDLKILAD SGIRTGLDVV
360 370 380 390 400
RMLALGADTV LLGRAFVYAL AAQGEAGVAN LLDLIAKEMR VAMTLTGARR
410
IADIGRDSLV NLP
Length:413
Mass (Da):44,785
Last modified:May 29, 2013 - v1
Checksum:i961CBCC38FDD19EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CALM01000777 Genomic DNA Translation: CCP17004.1

Genome annotation databases

EnsemblBacteriaiCCP17004; CCP17004; SMRA8_2776

Similar proteinsi

Entry informationi

Entry nameiM5CZY6_STEMA
AccessioniPrimary (citable) accession number: M5CZY6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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