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Entry version 52 (11 Dec 2019)
Sequence version 1 (29 May 2013)
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Protein
Submitted name:

Salt overly sensitive 1

Gene

sos1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiportSAAS annotation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Salt overly sensitive 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sos1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei129 – 148HelicalSequence analysisAdd BLAST20
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Transmembranei232 – 251HelicalSequence analysisAdd BLAST20
Transmembranei258 – 276HelicalSequence analysisAdd BLAST19
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Transmembranei314 – 335HelicalSequence analysisAdd BLAST22
Transmembranei355 – 376HelicalSequence analysisAdd BLAST22
Transmembranei388 – 406HelicalSequence analysisAdd BLAST19
Transmembranei426 – 451HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 449Na_H_ExchangerInterPro annotationAdd BLAST412

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni981 – 1001DisorderedSequence analysisAdd BLAST21
Regioni1102 – 1128DisorderedSequence analysisAdd BLAST27

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1965 Eukaryota
COG0025 LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
SMINDMK

Database of Orthologous Groups

More...
OrthoDBi
99426at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006153 Cation/H_exchanger
IPR018422 Cation/H_exchanger_CPA1
IPR018490 cNMP-bd-like

The PANTHER Classification System

More...
PANTHERi
PTHR10110 PTHR10110, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00999 Na_H_Exchanger, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51206 SSF51206, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M5BF34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTVIDATMA YRFLEEATDS SSSSSSSKLE SSPVDAVLFV GMSLVLGIAS
60 70 80 90 100
RHLLRGTRVP YTVALLVIGI ALGSLEYGAK HNLGKIGHGI RIWNEIDPEL
110 120 130 140 150
LLAVFLPALL FESSFSMEVH QIKRCLGQMV LLAVPGVLIS TACLGSLVKV
160 170 180 190 200
TFPYEWDWKT SLLLGGLLSA TDPVAVVALL KELGASKKLS TIIEGESLMN
210 220 230 240 250
DGTAIVVFQL FLKMAMGQNS DWSSIIKFLL KVALGAVGIG LAFGIASVIW
260 270 280 290 300
LKFIFNDTVI EITLTIAVSY FAYYTAQEWA GASGVLTVMT LGMFYAAFAR
310 320 330 340 350
TAFKGDSQKS LHHFWEMVAY IANTLIFILS GVVIAEGILD SDKIAYQGNS
360 370 380 390 400
WRFLFLLYVY IQLSRVVVVG VLYPLLCRFG YGLDWKESII LVWSGLRGAV
410 420 430 440 450
ALALSLSVKQ SSGNSHISKE TGTLFLFFTG GIVFLTLIVN GSTTQFVLRL
460 470 480 490 500
LRMDILPAPK KRILEYTKYE MLNKALRAFQ DLGDDEELGP ADWPTVESYI
510 520 530 540 550
SSLKGSEGEL VHHPHNGSKI GSLDPKSLKD IRMRFLNGVQ ATYWEMLDEG
560 570 580 590 600
RISEVTANIL MQSVDEALDQ VSTTLCDWRG LKPHVNFPNY YNFLHSKVVP
610 620 630 640 650
RKLVTYFAVE RLESACYISA AFLRAHTIAR QQLYDFLGES NIGSIVINES
660 670 680 690 700
EKEGEEAKKF LEKVRSSFPQ VLRVVKTKQV TYSVLNHLLG YIENLEKVGL
710 720 730 740 750
LEEKEIAHLH DAVQTGLKKL LRNPPIVKLP KLSDMITSHP LSVALPPAFC
760 770 780 790 800
EPLKHSKKEP MKLRGVTLYK EGSKPTGVWL IFDGIVKWKS KILSNNHSLH
810 820 830 840 850
PTFSHGSTLG LYEVLTGKPY LCDLITDSMV LCFFIDSEKI LSLQSDSTID
860 870 880 890 900
DFLWQESALV LLKLLRPQIF ESVAMQELRA LVSTESSKLT TYVTGESIEI
910 920 930 940 950
DCNSIGLLLE GFVKPVGIKE ELISSPAALS PSNGNQSFHN SSEASGIMRV
960 970 980 990 1000
SFSQQATQYI VETRARAIIF NIGAFGADRT LHRRPSSLTP PRSSSSDQLQ
1010 1020 1030 1040 1050
RSFRKEHRGL MSWPENIYAK QQQEINKTTL SLSERAMQLS IFGSMVNVYR
1060 1070 1080 1090 1100
RSVSFGGIYN NKLQDNLLYK KLPLNPAQGL VSAKSESSIV TKKQLETRKH
1110 1120 1130 1140
ACQLPLKGES STRQNTMVES SDEEDEDEGI VVRIDSPSKI VFRNDL
Length:1,146
Mass (Da):127,188
Last modified:May 29, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDAEA315426F8AE7A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HE802926 Genomic DNA Translation: CCH26570.1
HE802935 Genomic DNA Translation: CCH26579.1
HE802943 Genomic DNA Translation: CCH26587.1

NCBI Reference Sequences

More...
RefSeqi
NP_178307.2, NM_126259.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G01980.1; AT2G01980.1; AT2G01980

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
814729

Gramene; a comparative resource for plants

More...
Gramenei
AT2G01980.1; AT2G01980.1; AT2G01980

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G01980

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE802926 Genomic DNA Translation: CCH26570.1
HE802935 Genomic DNA Translation: CCH26579.1
HE802943 Genomic DNA Translation: CCH26587.1
RefSeqiNP_178307.2, NM_126259.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblPlantsiAT2G01980.1; AT2G01980.1; AT2G01980
GeneIDi814729
GrameneiAT2G01980.1; AT2G01980.1; AT2G01980
KEGGiath:AT2G01980

Phylogenomic databases

eggNOGiKOG1965 Eukaryota
COG0025 LUCA
OMAiSMINDMK
OrthoDBi99426at2759

Family and domain databases

InterProiView protein in InterPro
IPR006153 Cation/H_exchanger
IPR018422 Cation/H_exchanger_CPA1
IPR018490 cNMP-bd-like
PANTHERiPTHR10110 PTHR10110, 1 hit
PfamiView protein in Pfam
PF00999 Na_H_Exchanger, 1 hit
SUPFAMiSSF51206 SSF51206, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM5BF34_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M5BF34
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: December 11, 2019
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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