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Protein

L-lactate dehydrogenase

Gene

lldD

Organism
Xanthomonas axonopodis Xac29-1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.UniRule annotationSAAS annotation

Catalytic activityi

(S)-lactate + an oxidized electron acceptor = pyruvate + a reduced electron acceptor.UniRule annotationSAAS annotation

Cofactori

FMNUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei24SubstrateUniRule annotation1
Binding sitei106FMNUniRule annotation1
Binding sitei127FMNUniRule annotation1
Binding sitei129SubstrateUniRule annotation1
Binding sitei155FMNUniRule annotation1
Binding sitei164SubstrateUniRule annotation1
Binding sitei251FMNUniRule annotation1
Active sitei275Proton acceptorUniRule annotation1
Binding sitei278SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi306 – 330FMNUniRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
LigandFlavoprotein, FMNUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
L-lactate dehydrogenaseUniRule annotationSAAS annotation (EC:1.1.-.-UniRule annotationSAAS annotation)
Gene namesi
Name:lldDUniRule annotationImported
ORF Names:XAC29_00670Imported
OrganismiXanthomonas axonopodis Xac29-1Imported
Taxonomic identifieri1304892 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000011979 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane SAAS annotation; Peripheral membrane protein SAAS annotation
  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneSAAS annotation, Cell membrane, Membrane

Structurei

3D structure databases

ProteinModelPortaliM4TNG3
SMRiM4TNG3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 380FMN hydroxy acid dehydrogenaseInterPro annotationAdd BLAST380

Sequence similaritiesi

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00101

Family and domain databases

CDDicd02809 alpha_hydroxyacid_oxid_FMN, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_01559 L_lact_dehydr, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR012133 Alpha-hydoxy_acid_DH_FMN
IPR000262 FMN-dep_DH
IPR037396 FMN_HAD
IPR008259 FMN_hydac_DH_AS
IPR020920 LldD
PfamiView protein in Pfam
PF01070 FMN_dh, 1 hit
PIRSFiPIRSF000138 Al-hdrx_acd_dh, 1 hit
PROSITEiView protein in PROSITE
PS00557 FMN_HYDROXY_ACID_DH_1, 1 hit
PS51349 FMN_HYDROXY_ACID_DH_2, 1 hit

Sequencei

Sequence statusi: Complete.

M4TNG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIISAASDYR AAAEARLPPF LFHYIDGGAY AEHTLRRNVS DLADVALRQR
60 70 80 90 100
VLRNMSDLRL STELFGETLA MPVALAPVGL TGMYARRGEV QAARAAAARG
110 120 130 140 150
IPFTLSTVSV CPIEEVAPAI ERPMWFQLYV LKDRGFMRNA LERAKAAGVT
160 170 180 190 200
TLVFTVDMPT PGARYRDAHS GMSGPNASLR RMLQAVTHPR WAWDVGLLGK
210 220 230 240 250
PHDLGNISAY RGSPTGLQDY IGWLGANFDP SIAWKDLEWI REFWTGPMVI
260 270 280 290 300
KGILDPEDAR DAVRFGADGI VVSNHGGRQL DGVLSSARAL PAIADAVKGE
310 320 330 340 350
LKILADSGIR SGLDVVRMLA LGADAVLLGR AFVYALAAAG QAGVENLLTL
360 370 380
IEKEMRVAMT LTGTHSIADI SADALSRVTR ERADAISP
Length:388
Mass (Da):41,830
Last modified:May 29, 2013 - v1
Checksum:iE60891DE3F3D5FC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004399 Genomic DNA Translation: AGH75668.1
RefSeqiWP_011050112.1, NC_020800.1

Genome annotation databases

EnsemblBacteriaiAGH75668; AGH75668; XAC29_00670
KEGGixao:XAC29_00670
PATRICifig|1304892.4.peg.148

Similar proteinsi

Entry informationi

Entry nameiM4TNG3_9XANT
AccessioniPrimary (citable) accession number: M4TNG3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: March 28, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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