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Entry version 43 (02 Jun 2021)
Sequence version 1 (29 May 2013)
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Protein
Submitted name:

Toxin B

Gene

tcdB

Organism
Clostridioides difficile (Peptoclostridium difficile)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferaseImportedARBA annotation, Hydrolase, Protease, Thiol proteaseARBA annotation, ToxinARBA annotation, Transferase
Biological processVirulenceARBA annotation
LigandMagnesiumARBA annotation, ManganeseARBA annotation, Metal-bindingARBA annotation, ZincARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Toxin BImported (EC:2.4.1.-Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tcdBImported
ORF Names:SAMEA708418_03270Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiClostridioides difficile (Peptoclostridium difficile)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1496 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesClostridiaEubacterialesPeptostreptococcaceaeClostridioides
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000290949 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Host cell membraneARBA annotation, Host cytoplasmARBA annotation, Host endosomeARBA annotation, Host membrane, Membrane, SecretedARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

Autocatalytic cleavageARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini568 – 775Peptidase C80InterPro annotationAdd BLAST208
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1833 – 1852Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati1854 – 1873Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati1876 – 1895Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati1926 – 1945Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati1967 – 1986Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati1987 – 2006Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2007 – 2026Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2057 – 2076Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2077 – 2097Cell wall-bindingPROSITE-ProRule annotationAdd BLAST21
Repeati2099 – 2118Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2119 – 2138Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2139 – 2158Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2209 – 2231Cell wall-bindingPROSITE-ProRule annotationAdd BLAST23
Repeati2233 – 2252Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2253 – 2272Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2273 – 2292Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2323 – 2342Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20
Repeati2343 – 2362Cell wall-bindingPROSITE-ProRule annotationAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the clostridial glucosylating toxin (LCGT) family.ARBA annotation

Keywords - Domaini

RepeatARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.11050, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018337, Cell_wall/Cho-bd_repeat
IPR020974, CPD_dom
IPR038383, CPD_dom_sf
IPR029044, Nucleotide-diphossugar_trans
IPR024770, TcdA/TcdB_cat
IPR024772, TcdA/TcdB_N
IPR024769, TcdA/TcdB_pore_forming

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01473, Choline_bind_1, 2 hits
PF19127, Choline_bind_3, 2 hits
PF11713, Peptidase_C80, 1 hit
PF12919, TcdA_TcdB, 1 hit
PF12920, TcdA_TcdB_pore, 1 hit
PF12918, TcdB_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448, SSF53448, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51771, CGT_MARTX_CPD, 1 hit
PS51170, CW, 18 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M4NKV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLVNRKQLE KMANVRFRVQ EDEYVAILDA LEEYHNMSEN TVVEKYLKLK
60 70 80 90 100
DINSLTDTYI DTYKKSGRNK ALKKFKEYLV IEILELKNSN LTPVEKNLHF
110 120 130 140 150
IWIGGQINDT AINYINQWKD VNSDYNVNVF YDSNAFLINT LKKTIIESAS
160 170 180 190 200
NDTLESFREN LNDPEFNHTA FFRKRMQIIY DKQQNFINYY KAQKEENPDL
210 220 230 240 250
IIDDIVKTYL SNEYSKDIDE LNAYIEESLN KVTENSGNDV RNFEEFKTGE
260 270 280 290 300
VFNLYEQELV ERWNLAGASD ILRVAILKNI GGVYLDVDML PGIHPDLFKD
310 320 330 340 350
INKPDSVKTA VDWEEMQLEA IMKHKEYIPE YTSKHFDTLD EEVQSSFESV
360 370 380 390 400
LASKSDKSEI FLPLGDIEVS PLEVKIAFAK GSIINQALIS AKDSYCSDLL
410 420 430 440 450
IKQIQNRYKI LNDTLGPIIS QGNDFNTTMN NFGESLGAIA NEENISFIAK
460 470 480 490 500
IGSYLRVGFY PEANTTITLS GPTIYAGAYK DLLTFKEMSI DTSILSSELR
510 520 530 540 550
NFEFPKVNIS QATEQEKNSL WQFNEERAKI QFEEYKKNYF EGALGEDDNL
560 570 580 590 600
DFSQNTVTDK EYLLEKISSS TKSSERGYVH YIVQLQGDKI SYEAACNLFA
610 620 630 640 650
KNPYDSILFQ KNIEDSEVAY YYNPTDSEIQ EIDKYRIPDR ISDRPKIKLT
660 670 680 690 700
FIGHGKAEFN TDIFAGLDVD SLSSEIETAI GLAKEDISPK SIEINLLGCN
710 720 730 740 750
MFSYSVNVEE TYPGKLLLRV KDKVSELMPS MSQDSIIVSA NQYEVRINSE
760 770 780 790 800
GRRELLDHSG EWINKEESII KDISSKEYIS FNPKENKIIV KSKNLPELST
810 820 830 840 850
LLQEIRNNSN SSDIELEEKV MLAECEINVI SNIETQVVEE RIEEAKSLTS
860 870 880 890 900
DSINYIKNEF KLIESISDAL CDLKQQNELE DSHFISFEDI SETDEGFSIR
910 920 930 940 950
FINKETGESI FVETEKTIFS EYANHITEEI SKIKGTIFDT VNGKLVKKVN
960 970 980 990 1000
LDTTHEVNTL NAAFFIQSLI EYNSSKESLS NLSVAMKVQV YAQLFSTGLN
1010 1020 1030 1040 1050
TITDAAKVVE LVSTALDETI DLLPTLSEGL PIIATIIDGV SLGAAIKELS
1060 1070 1080 1090 1100
ETSDPLLRQE IEAKIGIMAV NLTTATTAII TSSLGIASGF SILLVPLAGI
1110 1120 1130 1140 1150
SAGIPSLVNN ELVLRDKATK VVDYFKHVSL VETEGVFTLL DDKVMMPQDD
1160 1170 1180 1190 1200
LVISEIDFNN NSIVLGKCEI WRMEGGSGHT VTDDIDHFFS APSITYREPH
1210 1220 1230 1240 1250
LSIYDVLEVQ KEELDLSKDL MVLPNAPNRV FAWETGWTPG LRSLENDGTK
1260 1270 1280 1290 1300
LLDRIRDNYE GEFYWRYFAF IADALITTLK PRYEDTNIRI NLDSNTRSFI
1310 1320 1330 1340 1350
VPIITTEYIR EKLSYSFYGS GGTYALSLSQ YNMGINIELS ESDVWIIDVD
1360 1370 1380 1390 1400
NVVRDVTIES DKIKKGDLIE GILSTLSIEE NKIILNSHEI NFSGEVNGSN
1410 1420 1430 1440 1450
GFVSLTFSIL EGINAIIEVD LLSKSYKLLI SGELKILMLN SNHIQQKIDY
1460 1470 1480 1490 1500
IGFNSELQKN IPYSFVDSEG KENGFINGST KEGLFVSELP DVVLISKVYM
1510 1520 1530 1540 1550
DDSKPSFGYY SNNLKDVKVI TKDNVNILTG YYLKDDIKIS LSLTLQDEKT
1560 1570 1580 1590 1600
IKLNSVHLDE SGVAEILKFM NRKGSTNTSD SLMSFLESMN IKSIFVNFLQ
1610 1620 1630 1640 1650
SNIKFILDAN FIISGTTSIG QFEFICDENN NIQPYFIKFN TLETNYTLYV
1660 1670 1680 1690 1700
GNRQNMIVEP NYDLDDSGDI SSTVINFSQK YLYGIDSCVN KVVISPNIYT
1710 1720 1730 1740 1750
DEINITPVYE TNNTYPEVIV LDANYINEKI NVNINDLSIR YVWSNDGNDF
1760 1770 1780 1790 1800
ILMSTSEENK VSQVKIRFVN VFKDKTLANK LSFNFSDKQD VPVSEIILSF
1810 1820 1830 1840 1850
TPSYYEDGLI GYDLGLVSLY NEKFYINNFG MMVSGLIYIN DSLYYFKPPV
1860 1870 1880 1890 1900
NNLITGFVTV GDDKYYFNPI NGGAASIGET IIDDKNYYFN QSGVLQTGVF
1910 1920 1930 1940 1950
STEDGFKYFA PANTLDENLE GEAIDFTGKL IIDENIYYFE DNYRGAVEWK
1960 1970 1980 1990 2000
ELDGEMHYFS PETGKAFKGL NQIGDDKYYF NSDGVMQKGF VSINDNKHYF
2010 2020 2030 2040 2050
DDSGVMKVGY TEIDGKHFYF AENGEMQIGV FNTEDGFKYF AHHNEDLGNE
2060 2070 2080 2090 2100
EGEEISYSGI LNFNNKIYYF DDSFTAVVGW KDLEDGSKYY FDEDTAEAYI
2110 2120 2130 2140 2150
GLSLINDGQY YFNDDGIMQV GFVTINDKVF YFSDSGIIES GVQNIDDNYF
2160 2170 2180 2190 2200
YIDDNGIVQI GVFDTSDGYK YFAPANTVND NIYGQAVEYS GLVRVGEDVY
2210 2220 2230 2240 2250
YFGETYTIET GWIYDMENES DKYYFDPETK KACKGINLID DIKYYFDEKG
2260 2270 2280 2290 2300
IMRTGLISFE NNNYYFNENG EMQFGYINIE DKMFYFGEDG VMQIGVFNTP
2310 2320 2330 2340 2350
DGFKYFAHQN TLDENFEGES INYTGWLDLD EKRYYFTDEY IAATGSVIID
2360
GEEYYFDPDT AQLVISE
Length:2,367
Mass (Da):269,323
Last modified:May 29, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i13E0261D57EC2104
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KC292128 Genomic DNA Translation: AGG91574.1
KC292139 Genomic DNA Translation: AGG91585.1
KC292142 Genomic DNA Translation: AGG91588.1
KC292146 Genomic DNA Translation: AGG91592.1
KC292149 Genomic DNA Translation: AGG91595.1
KC292152 Genomic DNA Translation: AGG91598.1
KC292156 Genomic DNA Translation: AGG91602.1
KC292160 Genomic DNA Translation: AGG91606.1
KC292163 Genomic DNA Translation: AGG91609.1
KC292164 Genomic DNA Translation: AGG91610.1
KC292165 Genomic DNA Translation: AGG91611.1
KC292166 Genomic DNA Translation: AGG91612.1
KC292170 Genomic DNA Translation: AGG91616.1
KC292175 Genomic DNA Translation: AGG91621.1
KC292180 Genomic DNA Translation: AGG91626.1
KC292182 Genomic DNA Translation: AGG91628.1
KC292188 Genomic DNA Translation: AGG91634.1
KC292191 Genomic DNA Translation: AGG91637.1
CAACYU010000016 Genomic DNA Translation: VFB60670.1

NCBI Reference Sequences

More...
RefSeqi
WP_003426838.1, NZ_WBMC01000088.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC292128 Genomic DNA Translation: AGG91574.1
KC292139 Genomic DNA Translation: AGG91585.1
KC292142 Genomic DNA Translation: AGG91588.1
KC292146 Genomic DNA Translation: AGG91592.1
KC292149 Genomic DNA Translation: AGG91595.1
KC292152 Genomic DNA Translation: AGG91598.1
KC292156 Genomic DNA Translation: AGG91602.1
KC292160 Genomic DNA Translation: AGG91606.1
KC292163 Genomic DNA Translation: AGG91609.1
KC292164 Genomic DNA Translation: AGG91610.1
KC292165 Genomic DNA Translation: AGG91611.1
KC292166 Genomic DNA Translation: AGG91612.1
KC292170 Genomic DNA Translation: AGG91616.1
KC292175 Genomic DNA Translation: AGG91621.1
KC292180 Genomic DNA Translation: AGG91626.1
KC292182 Genomic DNA Translation: AGG91628.1
KC292188 Genomic DNA Translation: AGG91634.1
KC292191 Genomic DNA Translation: AGG91637.1
CAACYU010000016 Genomic DNA Translation: VFB60670.1
RefSeqiWP_003426838.1, NZ_WBMC01000088.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6OQ5X-ray3.87A1-2367[»]
6OQ7X-ray2.39A1-543[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Family and domain databases

Gene3Di3.40.50.11050, 1 hit
InterProiView protein in InterPro
IPR018337, Cell_wall/Cho-bd_repeat
IPR020974, CPD_dom
IPR038383, CPD_dom_sf
IPR029044, Nucleotide-diphossugar_trans
IPR024770, TcdA/TcdB_cat
IPR024772, TcdA/TcdB_N
IPR024769, TcdA/TcdB_pore_forming
PfamiView protein in Pfam
PF01473, Choline_bind_1, 2 hits
PF19127, Choline_bind_3, 2 hits
PF11713, Peptidase_C80, 1 hit
PF12919, TcdA_TcdB, 1 hit
PF12920, TcdA_TcdB_pore, 1 hit
PF12918, TcdB_N, 1 hit
SUPFAMiSSF53448, SSF53448, 1 hit
PROSITEiView protein in PROSITE
PS51771, CGT_MARTX_CPD, 1 hit
PS51170, CW, 18 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM4NKV9_CLODI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M4NKV9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: June 2, 2021
This is version 43 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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