Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Genome polyprotein

Gene
N/A
Organism
Palm Creek virus
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation
NTP + H2O = NDP + phosphate.SAAS annotation
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase, MethyltransferaseSAAS annotation, Nucleotidyltransferase, RNA-bindingSAAS annotation, RNA-directed RNA polymeraseSAAS annotation, Transferase
Biological processActivation of host autophagy by virusSAAS annotation, Host-virus interaction, Inhibition of host innate immune response by virusSAAS annotation, Viral attachment to host cellSAAS annotation, Viral immunoevasion, Viral RNA replicationSAAS annotation, Virus entry into host cell
LigandATP-binding, Metal-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyproteinSAAS annotation
OrganismiPalm Creek virusImported
Taxonomic identifieri1302179 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageFlaviviridaeFlavivirus
Proteomesi
  • UP000155134 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei671 – 689HelicalSequence analysisAdd BLAST19
Transmembranei1147 – 1167HelicalSequence analysisAdd BLAST21
Transmembranei1187 – 1207HelicalSequence analysisAdd BLAST21
Transmembranei1282 – 1301HelicalSequence analysisAdd BLAST20
Transmembranei1321 – 1338HelicalSequence analysisAdd BLAST18
Transmembranei1419 – 1445HelicalSequence analysisAdd BLAST27
Transmembranei2109 – 2130HelicalSequence analysisAdd BLAST22
Transmembranei2169 – 2194HelicalSequence analysisAdd BLAST26
Transmembranei2206 – 2223HelicalSequence analysisAdd BLAST18
Transmembranei2243 – 2263HelicalSequence analysisAdd BLAST21
Transmembranei2322 – 2351HelicalSequence analysisAdd BLAST30
Transmembranei2389 – 2405HelicalSequence analysisAdd BLAST17

GO - Cellular componenti

Keywords - Cellular componenti

Capsid proteinSAAS annotation, Host membraneSAAS annotation, Membrane, Virion

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1466 – 1643Peptidase S7InterPro annotationAdd BLAST178
Domaini1658 – 1795Helicase ATP-bindingInterPro annotationAdd BLAST138
Domaini1789 – 1955Helicase C-terminalInterPro annotationAdd BLAST167
Domaini2476 – 2728MRNA cap 0-1 NS5-type MTInterPro annotationAdd BLAST253
Domaini2992 – 3139RdRp catalyticInterPro annotationAdd BLAST148

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili95 – 115Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di2.60.98.10, 1 hit
InterProiView protein in InterPro
IPR011492 DEAD_Flavivir
IPR001157 Flavi_NS1
IPR001850 Flavivirus_NS3_S7
IPR011998 Glycoprot_cen/dimer
IPR036253 Glycoprot_cen/dimer_sf
IPR038055 Glycoprot_E_dimer_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR026490 mRNA_cap_0/1_MeTrfase
IPR027417 P-loop_NTPase
IPR009003 Peptidase_S1_PA
IPR000208 RNA-dir_pol_flavivirus
IPR007094 RNA-dir_pol_PSvirus
IPR002877 rRNA_MeTrfase_FtsJ_dom
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF07652 Flavi_DEAD, 1 hit
PF00869 Flavi_glycoprot, 1 hit
PF00948 Flavi_NS1, 1 hit
PF00972 Flavi_NS5, 1 hit
PF01728 FtsJ, 1 hit
PF00271 Helicase_C, 1 hit
PF00949 Peptidase_S7, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF52540 SSF52540, 2 hits
SSF53335 SSF53335, 1 hit
SSF56983 SSF56983, 1 hit
PROSITEiView protein in PROSITE
PS51528 FLAVIVIRUS_NS3PRO, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS50507 RDRP_SSRNA_POS, 1 hit
PS51591 RNA_CAP01_NS5_MT, 1 hit

Sequencei

Sequence statusi: Complete.

M4N641-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNQERGILRG MGRFPPPPVK KGNKNSVAVA RVPPQQGGKA REKNRERIKA
60 70 80 90 100
PGARHGVAGK MKSLMGELGF GWIDLLRVDL VEGIMMMVFV IQRAFAQVHR
110 120 130 140 150
RIRGLSRRVR ALEKKRDGRA AMFIWTILAM LFGVMGVVVI DMRVTYDGQV
160 170 180 190 200
QIYRDGENMT DRVALFKLPT DGCSVGLPVS KMCHKVDKNM KEGLADTDCG
210 220 230 240 250
STWAEFRLRY QRCQVKTRAK RVAPDGPKQD FLAEVEIVAF KAIRENKSVL
260 270 280 290 300
LVVVLCVAIA KRWPLWVLIL LSIGTWTTVR GEYMEPLYVL KADQMTMIQT
310 320 330 340 350
TLRPEEGYVT ATANGLFEMK TGRAFIYGSQ VVKTLVTDCE VNATYSTDIC
360 370 380 390 400
PGGSQLSMQD IQAEGRACAS EPYNRGWGTG CFKWGVGFVA TCAEVDCTTS
410 420 430 440 450
VKVSSVARST IKMNVTATYH SVKSVQSVIS DVPVTFQFGQ LGIASMTCRL
460 470 480 490 500
ESDRIAQSYY HVEGNKKEGL FMKEQIDGWN GATLAAGKIA NTEKIVIWGD
510 520 530 540 550
VKPNEILVKA VSEPQLEWTN AIATHDGFRD VGFVCQIMLD KLVTGVFKDC
560 570 580 590 600
KTPKTSTFTQ SGFGFDGIIT TTLAVAQTEA CSISISCKGC TLLATKAVFS
610 620 630 640 650
AGDIESKTWV RCGNESGTAI VGGQEVAVAC ATNPITQGWR LVKHATQRYR
660 670 680 690 700
KFGMPGVGGV FHDLVGTLNP WSFFSTTTLV FMAVVLFIVD KRILILGIAC
710 720 730 740 750
YMFYFVRADF GCGFDPDRKV AQCGSGSFVW KSLARWPMAD HAIEFEDSKV
760 770 780 790 800
MVTYLTDLLM RKNKVCIVCE DVLQCAAARG VVEQITSING IPIHHNMSLS
810 820 830 840 850
HGRYFPRVVK KVHNVKVGKA MLRLAMATYA GAMPESGLGV LKTGYFSRGE
860 870 880 890 900
VQETWDDKVL RVLTSAINAE EVCQTAVTFQ YEFVRYNRKV FGSNIVLRPS
910 920 930 940 950
AFTSKACPTY LAGAVVKNDI ATFTDGMMWM RSRKVNETWE LFELETTQSH
960 970 980 990 1000
QCIWPYAYTI DLATPTDKRL FMPPQYGGPI SFANHVPGFQ VQEDFPWQKA
1010 1020 1030 1040 1050
NILMRQGPVP GTTVVQDPHC DDRSAAVPVE PTMQAWCCKT CFDRGVKPFH
1060 1070 1080 1090 1100
FVVDGKFFYP MEVRPMKLEQ DAVVIETDDG EFERSEHESL FEGKAKWTSP
1110 1120 1130 1140 1150
LPMGETAKIQ NFFVTSPPKP ESSLLLVGVL IHMLTTRTRH RWATRCAGTW
1160 1170 1180 1190 1200
LIFLVFGHPV VSSVQSWAWL FMSAALASVP GGSSLVIHFW IGLQISSAHL
1210 1220 1230 1240 1250
FYLGWLMRKR LLITEMSRVA HLIAQLCSFE TYAWAPILKV LDHLLFPLYT
1260 1270 1280 1290 1300
LSVFVVHQQF QVFHDLWLQS AVVMAHLLQH PLSGLITLSL SVGLIQLIAP
1310 1320 1330 1340 1350
MKRWFCSPVI WGDGLRAPRP HWTALTYFIV LYLAAAGMET VGLHTSGMTV
1360 1370 1380 1390 1400
MLGGMLLWVV LQLMPPTALE LVRLPGQSLP DGCEEEASTS LPEGMSGHYA
1410 1420 1430 1440 1450
PDGVELVNYT DAGTVSANLV VFVGCAGIMT MNIYVGLVIT ALAWVTDAPM
1460 1470 1480 1490 1500
WIPRLIDGAM SQRANSELLL PSPPLEIHKT EDSFGYIPDG TYHVLASSWM
1510 1520 1530 1540 1550
SKKPVGVGVV KEGVFHTLHH VTKGANVTWA GREVRMHSGD VRRDIAAYGG
1560 1570 1580 1590 1600
PWNISGSLED VVVVKAVNKD GTVTCCRITT AKLDIEGTTV MAVERDFGFG
1610 1620 1630 1640 1650
SSGSPIYAPD GRLIGLYGYG FYYGTYFSIV STGEGVEAPP EEVEVSTREF
1660 1670 1680 1690 1700
VDWHPGRGKT RTILVEQALK HIADGKRLLI LTPTRVVKDE VQRAIKEAAP
1710 1720 1730 1740 1750
QAVIGSNLSI FRKNAVTLAC HATFTQYVME KGIESVKFST IIMDECHFLD
1760 1770 1780 1790 1800
PMSIACRGIM DFHNSRGTKV IFMSATPPGR AGNAGSNFTI EDRAIKFPKE
1810 1820 1830 1840 1850
LTASWIKDKS IGKTIVFVPT ITQAVRLAKE LGGVALTRDT FNDAMGKARS
1860 1870 1880 1890 1900
PETMFIISTD ISEMGANLGV TTVIDTRTVI KPLVSDKGVS LERVGVTPAS
1910 1920 1930 1940 1950
IIQRRGRVGR REPGVYIYPL DVEPEEQPEN WVCWVEAQMI LDQLGCHPMR
1960 1970 1980 1990 2000
EESEFFRPQG TYRIDDVEQR RFLGLIKEKL PIWLAWTWAS SHANKHQMLF
2010 2020 2030 2040 2050
QGNAPNTGRT LKIKTPSGSH IYAPKVTDDR FEKEPEIVKV AAIGFFLKQR
2060 2070 2080 2090 2100
SLYFDLPGLL TGLYTVLTTA GLDALGNSFK RSVDTLHDIG NAVEGEFSAI
2110 2120 2130 2140 2150
QMGRILQMWS ALFIGVTLGV VLMGAGFVVV KAFRGLFGTR QQHTTVCVSE
2160 2170 2180 2190 2200
GGSFQKVATV LMSVGPLCAV FGGIPSIFVF IVTVALLIVL CVGGGGSQRG
2210 2220 2230 2240 2250
VLDSDLIRWV MVLAMMTIGV TAWELELLPN VRRDVIQLTR YLFASNPAVV
2260 2270 2280 2290 2300
GAVFNAGNIG LGVSLPGTLM MSYAASGTLA PLIGAWAEGN FLGKLFGSEV
2310 2320 2330 2340 2350
LPAQAIGGFQ VTAIPWGSMV PVIAGCFLAT NTLSKVFGAG ITTVFLILLY
2360 2370 2380 2390 2400
FDKKHAFTNK AVKVLLARTN RRDMEEEITT RDAESRARQL FYGLQLAVSL
2410 2420 2430 2440 2450
LWVLSHPVLE NFVPFFAVCG YTFLSLLRPN HQLHAALDYT LVVLLLQVVE
2460 2470 2480 2490 2500
PGNIMYVGGC VLLWYVLNPT RLGVRSLVKS DTGGLGFRWK KALNSLSERQ
2510 2520 2530 2540 2550
FAIYKVRGVN ETDKGAYVSR GGLKMNEIIN KHAWEPRGVV VDLGCGRGGW
2560 2570 2580 2590 2600
SQRLVMDYRV AEVRGYTLGG KERENPQPFQ TKGYNLANLK AGVDVYKMEP
2610 2620 2630 2640 2650
VNCNTIICDI GESDPRPEVE KTRTLKVLGM LEKWLEVNPN ASFCCKVLSP
2660 2670 2680 2690 2700
YHLDVLRKLE SLQHKYNGRL VRLSYSRNST AEMYYVSGKR ANVVASVYFM
2710 2720 2730 2740 2750
LGSLVGRLRR HEPSIIDPPP VLEMGTRSDP RAKAKAQDFE MIRRRVERLR
2760 2770 2780 2790 2800
GENRKTWFVD NEHPYVSFNY HGSFVTDEVT AGGQTTNPLI RRVMWPWDFL
2810 2820 2830 2840 2850
SRVTTFMMTD VSTYAQQKVL REKVDTVSEE PDERMKAINR LIMTHFVKMF
2860 2870 2880 2890 2900
KRRGLKPRVL TPQDYMNNVQ ANAAIGGWSE VMDWQNVRDA LADQRFWDMV
2910 2920 2930 2940 2950
DNERALHLRG DCELCIYNTM GKKEKKPSAF GTAKGSRTIW YMWLGSRYLE
2960 2970 2980 2990 3000
YEALGFLNED HWVARENFPC GVGGVGVNYF GYYLKEIAGG GRWLIADDVA
3010 3020 3030 3040 3050
GWDTRITQGD LDDELFMLTE LAPTTYHKKL ITATMTLAYK NIVALFPRNH
3060 3070 3080 3090 3100
PMYRSGTVLD VLSRTDQRGS GQVTTYALNT VTNGKCQVGR TLEACGLLDA
3110 3120 3130 3140 3150
PLTTIDSWLT ANLERVLGAM VVAGDDVVVA TDNEEFHTSL RYITATSKIR
3160 3170 3180 3190 3200
KNLGVSEPSP RFTSWEDVEF CSHHFHPLTL RDGRVLIAPC RDQNEIIGRS
3210 3220 3230 3240 3250
RIQKGGIVDM ASAGCLAKAH AQMWALYFFH RRDLRIGFAA ITSIVPINWV
3260 3270 3280 3290 3300
PTGRISWSIH QNAEWMTTED MLTVWNNVWI RDNPWMRGKE RVTSWTDIPY
3310 3320 3330 3340 3350
LPKGVDIKCG SLIGDSDRAS WSKTIPLVVE KTRKILEQER GTLKFYNGLS
3360
ILGRYVHHVD PVFN
Length:3,364
Mass (Da):374,183
Last modified:May 29, 2013 - v1
Checksum:iA3A43FB8CF722A3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC505248 Genomic RNA Translation: AGG76014.1
RefSeqiYP_009344962.1, NC_033694.1

Genome annotation databases

GeneIDi30999489
KEGGivg:30999489

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC505248 Genomic RNA Translation: AGG76014.1
RefSeqiYP_009344962.1, NC_033694.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30999489
KEGGivg:30999489

Family and domain databases

Gene3Di2.60.98.10, 1 hit
InterProiView protein in InterPro
IPR011492 DEAD_Flavivir
IPR001157 Flavi_NS1
IPR001850 Flavivirus_NS3_S7
IPR011998 Glycoprot_cen/dimer
IPR036253 Glycoprot_cen/dimer_sf
IPR038055 Glycoprot_E_dimer_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR026490 mRNA_cap_0/1_MeTrfase
IPR027417 P-loop_NTPase
IPR009003 Peptidase_S1_PA
IPR000208 RNA-dir_pol_flavivirus
IPR007094 RNA-dir_pol_PSvirus
IPR002877 rRNA_MeTrfase_FtsJ_dom
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF07652 Flavi_DEAD, 1 hit
PF00869 Flavi_glycoprot, 1 hit
PF00948 Flavi_NS1, 1 hit
PF00972 Flavi_NS5, 1 hit
PF01728 FtsJ, 1 hit
PF00271 Helicase_C, 1 hit
PF00949 Peptidase_S7, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF52540 SSF52540, 2 hits
SSF53335 SSF53335, 1 hit
SSF56983 SSF56983, 1 hit
PROSITEiView protein in PROSITE
PS51528 FLAVIVIRUS_NS3PRO, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS50507 RDRP_SSRNA_POS, 1 hit
PS51591 RNA_CAP01_NS5_MT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM4N641_9FLAV
AccessioniPrimary (citable) accession number: M4N641
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again