Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
N/A
Organism
Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N7-methylguanine(46) in tRNA.UniRule annotationSAAS annotation

Pathwayi: N(7)-methylguanine-tRNA biosynthesis

This protein is involved in the pathway N(7)-methylguanine-tRNA biosynthesis, which is part of tRNA modification.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway N(7)-methylguanine-tRNA biosynthesis and in tRNA modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei71S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei148S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Active sitei151UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotation, RNA-binding, Transferase, tRNA-bindingUniRule annotationSAAS annotation
Biological processtRNA processingUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00989

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
OrganismiBrassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)Imported
Taxonomic identifieri51351 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica
Proteomesi
  • UP000011750 Componenti: Chromosome A06

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi3711.Bra009797.1-P

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni94 – 95S-adenosyl-L-methionine bindingUniRule annotation2
Regioni128 – 129S-adenosyl-L-methionine bindingUniRule annotation2
Regioni226 – 228S-adenosyl-L-methionine bindingUniRule annotation3

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotationSAAS annotation

Phylogenomic databases

InParanoidiM4D000
OMAiIGMEIRV
OrthoDBiEOG09360OC8

Family and domain databases

HAMAPiMF_03055 tRNA_methyltr_TrmB_euk, 1 hit
InterProiView protein in InterPro
IPR029063 SAM-dependent_MTases
IPR025763 Trm8_euk
IPR003358 tRNA_(Gua-N-7)_MeTrfase_Trmb
PANTHERiPTHR23417 PTHR23417, 1 hit
PTHR23417:SF16 PTHR23417:SF16, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00091 TIGR00091, 1 hit
PROSITEiView protein in PROSITE
PS51625 SAM_MT_TRMB, 1 hit

Sequencei

Sequence statusi: Complete.

M4D000-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESETKPTFS KSTGLPRKRF YRARAHSNPL SDSHFPIPIS PSHLDFSLHF
60 70 80 90 100
PKFFGANNEE VSKKAEFADI GCGFGGLLIS LATLFPDTLM IGMELRDKVT
110 120 130 140 150
EYVKERILAL RKSSSGGQYE KVSVVRTNSM KYIPNYFEKG QLSKMFFLFP
160 170 180 190 200
DPHFKEKNHR RRVISVDLLD EYAYVLRAGG IIYTITDVEE LGEWMRSCLE
210 220 230 240 250
KHPMFESLTQ DELDSDPVVE LLCSATEEGQ KVARNGGQTF RAVFRRIAYV

S
Length:251
Mass (Da):28,639
Last modified:May 1, 2013 - v1
Checksum:i192B4FD3D6D9EE30
GO

Genome annotation databases

EnsemblPlantsiBra009797.1; Bra009797.1-P; Bra009797
GrameneiBra009797.1; Bra009797.1-P; Bra009797

Similar proteinsi

Entry informationi

Entry nameiM4D000_BRARP
AccessioniPrimary (citable) accession number: M4D000
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health