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Protein

DNA polymerase

Gene
N/A
Organism
Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent) (Peronospora arabidopsidis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
OrganismiHyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent) (Peronospora arabidopsidis)Imported
Taxonomic identifieri559515 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesOomycetesPeronosporalesPeronosporaceaeHyaloperonospora
Proteomesi
  • UP000011713 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272952.HpaP803887

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 90DNA_pol_alpha_NInterPro annotationAdd BLAST72
Domaini441 – 810DNA_pol_B_exo1InterPro annotationAdd BLAST370
Domaini872 – 1350DNA_pol_BInterPro annotationAdd BLAST479
Domaini1392 – 1590zf-DNA_PolInterPro annotationAdd BLAST199

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1036 – 1056Sequence analysisAdd BLAST21
Coiled coili1536 – 1556Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerUniRule annotation

Phylogenomic databases

InParanoidiM4BC72
OMAiPKDCIFP

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR024647 DNA_pol_a_cat_su_N
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF12254 DNA_pol_alpha_N, 1 hit
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 2 hits
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Complete.

M4BC72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSRRAGAPR GNSSRKQALE DIKRMRDGDA SAVPVSGSRL AQYKPQEDSI
60 70 80 90 100
YKAMSEQEYE DLVRQRRQGL PFVENDDGEM GYYDDGEEQF FESDGDDDDA
110 120 130 140 150
AAAGNSHASK HKSNDSDDAS GKKRSAGALS SSYVRHAKKM QRAKLGGAGA
160 170 180 190 200
GGEGQKIANL FFSKSTTTGQ MLHKDRSSGH AGTSTGASTR AKYDMDLDSL
210 220 230 240 250
LDDLTSNPTA SRQCYVPPVS YSTGSLTFPS RATSASSVQP RGAAVTAKSV
260 270 280 290 300
VSSVDEDEDE TMEESGDLDE RLIEHDEMDG DDVEDERADE AEYNHVSERE
310 320 330 340 350
QNGDELETED GGVNKPVMSK RERMLQKARE ARLQSSAPTA RALSAPVEPK
360 370 380 390 400
NQLEDRTQMA AVPSNEVTEW WQVGGDQSND VSMVDASSVE NAEPEASPVA
410 420 430 440 450
VDSVQMYWMD AVEVRERPGK IYLIGKMKVA SPDGSSKPPT YKSCCVVVNN
460 470 480 490 500
LQRCMYLVPK GTSLIDLSKN EQQEVWMKMH EEVHNVLVPS CITSKRDQEE
510 520 530 540 550
FRTKLVERNY AFEEGSIPRG KNLYLKVKYL SKYPAPPTDF CSRGGKTFSR
560 570 580 590 600
ICGAFTRPLE NFLLTRRLLG PGWVEISNVR KCTEGISFCK AEYETFDPKN
610 620 630 640 650
VTPIASGMAA PPLTVMSISL KSVCHPMTGK HEIVALSAIT ETGISAEGAG
660 670 680 690 700
KGRNGARHTL SHFTAIRPLD GNSGFPQSYA EAAKRDDRFG TKAENGALSI
710 720 730 740 750
NSERLRVEIN ERVMLSYFLT RVQLEDPDVI VGHNLHKYGL ELLISRIDNF
760 770 780 790 800
KLGGLWSKLT RLRRGRLNPM NVGEGWNEYR MDDMVNGRLF CDTYVSSKEL
810 820 830 840 850
LPSQNNYTLS FLVEEHLHKQ RLDVEMTEIP QILLGGPDNF VKLLRHTLDD
860 870 880 890 900
AMFVLHLMHK LEILPLSKHL SNLCGYLWTR TLEANKRAER IEYLLLHEFS
910 920 930 940 950
RSKNKFIVPE KYKTRTDADK LNKKREASYA GGMVFAPKKG LYDNFVVLLD
960 970 980 990 1000
FMSLYPSIIR EYNICFTTVE RQLITDVPDA HSSSKRKKKS KPTPQPENDD
1010 1020 1030 1040 1050
VVDDNEVDEH LDCTADSEIP ALPSSASEPG ILPAVIKRLL ESRKQVKLQL
1060 1070 1080 1090 1100
KIEQKEGNLE KAILLDIRQK AIKLTANSMY GCLGFRFSRF YAKPIAALIT
1110 1120 1130 1140 1150
STGRQTLQRA KEVAEQECGY DVVYGDTDSI MVDSRTENLD EAKRIGREIQ
1160 1170 1180 1190 1200
TQCNKHFRLL ELEVDYIFKR ILLLNKKKYA ALVLKERPNC EPTFDKEVKG
1210 1220 1230 1240 1250
LDMVRRDWCV ISKTVGNEVL DFILSGKSRD DVVESIHEHL EQVAERVRSG
1260 1270 1280 1290 1300
KEPIQQFVIT KSLNKLPEQY PDRAKQYHVQ VAIALRALGK PVGVGTHIPY
1310 1320 1330 1340 1350
VLCKEEEPGS GRRAYHPDEV KRAGEKLHID VEWYLESQIH PPVNRLCAHI
1360 1370 1380 1390 1400
EGTSSPQLAH CLGLDTAKFS HSVSHFGEEN DECDAIPSVL QNDADRFKDC
1410 1420 1430 1440 1450
IHLEITCDRC KTASAFPGVF CTSEKDSSVS SGLLCPVCKA NFWGFDQEGI
1460 1470 1480 1490 1500
YGNVGDDFQA VLSNRLHLAT RQATKRYYEA WTICSDVMCK MRTQKQSLRG
1510 1520 1530 1540 1550
NGNICSAAGC RATTVLEYPD SALYTQLKYF ESLFNAERAQ KKLREEKERV
1560 1570 1580 1590
SGTSTNVEHP VLSERHCAVL RKLLSQAEEA VHRDDYNWIK PSLWQTLFT
Length:1,599
Mass (Da):179,354
Last modified:May 1, 2013 - v1
Checksum:iF7589C8A2D3031FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH598126 Genomic DNA No translation available.

Genome annotation databases

EnsemblProtistsiHpaT803887; HpaP803887; HpaG803887

Similar proteinsi

Entry informationi

Entry nameiM4BC72_HYAAE
AccessioniPrimary (citable) accession number: M4BC72
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: April 25, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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