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Entry version 48 (07 Oct 2020)
Sequence version 2 (05 Dec 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8083 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaeXiphophorus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002852 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

AcetylationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8083.ENSXMAP00000003883

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini115 – 251BAHInterPro annotationAdd BLAST137
Domaini213 – 324ELM2InterPro annotationAdd BLAST112
Domaini328 – 380SANTInterPro annotationAdd BLAST53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 100DisorderedSequence analysisAdd BLAST100
Regioni400 – 431DisorderedSequence analysisAdd BLAST32
Regioni479 – 1023DisorderedSequence analysisAdd BLAST545
Regioni1058 – 1123DisorderedSequence analysisAdd BLAST66
Regioni1446 – 1472DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 45PolyampholyteSequence analysisAdd BLAST45
Compositional biasi400 – 423PolarSequence analysisAdd BLAST24
Compositional biasi493 – 508PolyampholyteSequence analysisAdd BLAST16
Compositional biasi514 – 560PolarSequence analysisAdd BLAST47
Compositional biasi561 – 618PolyampholyteSequence analysisAdd BLAST58
Compositional biasi625 – 648PolyampholyteSequence analysisAdd BLAST24
Compositional biasi649 – 700PolarSequence analysisAdd BLAST52
Compositional biasi719 – 756Pro-richSequence analysisAdd BLAST38
Compositional biasi771 – 795PolarSequence analysisAdd BLAST25
Compositional biasi796 – 854Pro-richSequence analysisAdd BLAST59
Compositional biasi899 – 920Pro-richSequence analysisAdd BLAST22
Compositional biasi932 – 950Pro-richSequence analysisAdd BLAST19
Compositional biasi951 – 971PolarSequence analysisAdd BLAST21
Compositional biasi1058 – 1103PolyampholyteSequence analysisAdd BLAST46

Keywords - Domaini

Zinc-fingerARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2133, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153615

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005292_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3ZNU0

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00202, ZnF_GATA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002951, Atrophin-like
IPR001025, BAH_dom
IPR043151, BAH_sf
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03154, Atrophin-1, 2 hits
PF01426, BAH, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00439, BAH, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51038, BAH, 1 hit
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M3ZNU0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTADKEKERE KERDRDRDRD RDKREAGKSR RQDGDRGESE SSRPRRSCTL
60 70 80 90 100
EGGAKNYAES EHSEDEDNDN GSTGGGSGTA EEAGKKGKKK MPKKKSRYER
110 120 130 140 150
TENGEITSFI TEDDVVYRPG DCVYIESRRP NTPYFICSIQ DFKLSKRDHL
160 170 180 190 200
LMNVKWYYRQ SEVPDSVYQH LVQDRNNEND SGRELVITDP VVRSRELFIS
210 220 230 240 250
DYVDTYHAAA LRGKCNISHF SDIFAAREFK AKLPELQPFP SPGGQAVTEN
260 270 280 290 300
EELVWMPGVN DCDLLMYLRA ARSMAAFAGM CDGGSTEDGC LAASRDDTTL
310 320 330 340 350
NALNTLHESS YDAGKALQRL VKKPVPKLIE KCWSEDEVKR FIKGLRQFGK
360 370 380 390 400
NFFRIRKELL PNKETGDLIT FYYYWKKTPE AASCRAHRRH RRQPVFRRIK
410 420 430 440 450
TRTASTPVNT PSRPPSSEFL DLSSASEDDF DSEDSEQELK GYACRHCFTT
460 470 480 490 500
TSKDWHHGGR ENILLCTDCR IHFKKYGELP PIEKPVDPPP FMFKPVKEEE
510 520 530 540 550
DGLGGKHSMR TRRNRGSMST LRSGRKKQTV SPDGRASPTN EDLRSSGRTS
560 570 580 590 600
PSAASTDSTD SKTDSMKKTS KKIKEEAPSP IKSAKRQREK GASDTEEPER
610 620 630 640 650
AKKSKTQELT RPDSPSECDG EGEGEGESSD GRSINEELSS DPKDIDQDNR
660 670 680 690 700
SSSPSIPSPR DNESDSDSSA QQQQLLQSQH PPVIQCQPGS SVASSAPVPP
710 720 730 740 750
TASAPSLPPQ VAPTAASTSL PPQPLPQTNP IPHHGPMPPM PHPLQPGPPL
760 770 780 790 800
LPHPHAMTPQ GFPVAASQVP PPPISGQSQQ RSHSPQPSSQ SGGQPPREQP
810 820 830 840 850
LPPASMPMPH IKPPPTTPIP QMPTPQSHKH PPHGSVPPFP QMPSNLPPPP
860 870 880 890 900
ALKPLSSLSN HHPPSAHPPP LQLMSGGQQL QPPPAQPPVL TQSQSLPPSA
910 920 930 940 950
SHQPPPPPPL PPPSVASHPG GAPQQPPFSS HPFSTALPPS GPPPSSSNSM
960 970 980 990 1000
PGLQPPSSSS APTSSISMPL PASVSCAPPS QAVPPVHIKE EPPDESEEPE
1010 1020 1030 1040 1050
SPPPPQRSPS PEPTVVNTPS HASQSARFYK YLDRGYNSCA RTDFYFTPLA
1060 1070 1080 1090 1100
SSKLAKKREE ALEKAKREAE QKAREEKERE KEKERERERE REKEVERAAK
1110 1120 1130 1140 1150
ASSSAHESRM GEPQMAGPTH MRPPFDGPPT TIAAVPPYIG PDTPALRTLS
1160 1170 1180 1190 1200
EYARPHVMSP TNRNHPFFVS LNPADPLLAY HMPGLYNADP AMRERELRER
1210 1220 1230 1240 1250
EMREREIRER ELRERMKPGF EVKPPEMDSL HPSTNPMEHF ARHGALTLPP
1260 1270 1280 1290 1300
MAGPHPFASF HPGLNPLERE RLGLPGPQLR PDMTYPERLA AERLHAERMA
1310 1320 1330 1340 1350
TVANDPIARL QMFNVTPHHH QHSHIHSHLH LHQQDPLHQG GGECLVCPPG
1360 1370 1380 1390 1400
SGAHPLAVDP LAAGPHLARF PYPPGAIPNP LLGQPPHEHE MLRHPVFGAP
1410 1420 1430 1440 1450
YPRDLPGGLP PQMSAAHQLQ AMHAMQSSGH AELQRLAMEQ QWLHGHHHMH
1460 1470
GGPLPGQEDY YSRLKKESDK QL
Length:1,472
Mass (Da):162,795
Last modified:December 5, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i11C555C3F1F9E5F3
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXMAT00000003888; ENSXMAP00000003883; ENSXMAG00000003866

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8083.ENSXMAP00000003883

Genome annotation databases

EnsembliENSXMAT00000003888; ENSXMAP00000003883; ENSXMAG00000003866

Phylogenomic databases

eggNOGiKOG2133, Eukaryota
GeneTreeiENSGT00940000153615
HOGENOMiCLU_005292_1_0_1
InParanoidiM3ZNU0

Family and domain databases

CDDicd00202, ZnF_GATA, 1 hit
Gene3Di2.30.30.490, 1 hit
InterProiView protein in InterPro
IPR002951, Atrophin-like
IPR001025, BAH_dom
IPR043151, BAH_sf
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA
PfamiView protein in Pfam
PF03154, Atrophin-1, 2 hits
PF01426, BAH, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit
SMARTiView protein in SMART
SM00439, BAH, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51038, BAH, 1 hit
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3ZNU0_XIPMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3ZNU0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: December 5, 2018
Last modified: October 7, 2020
This is version 48 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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