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Protein

Ribosomal protein S6 kinase

Gene
N/A
Organism
Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei104ATPUniRule annotation1
Active sitei199Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi78 – 86ATPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal protein S6 kinaseUniRule annotation (EC:2.7.11.1UniRule annotation)
OrganismiXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)Imported
Taxonomic identifieri8083 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaeXiphophorus
Proteomesi
  • UP000002852 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi8083.ENSXMAP00000000142

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 333Protein kinaseInterPro annotationAdd BLAST262
Domaini334 – 404AGC-kinase C-terminalInterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0598 Eukaryota
ENOG410XNPH LUCA
GeneTreeiENSGT00920000148962
InParanoidiM3ZD50
OMAiRSPRKFP
OrthoDBiEOG091G05Z7

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR016238 Ribosomal_S6_kinase
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
PIRSFiPIRSF000605 Ribsml_S6_kin_1, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

M3ZD50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DSSVADMAGV FDIDLDQPDE NVSDDELEDG TQHGEYMDQC SSFEFNMDGC
60 70 80 90 100
EKFEISENSV NKGTEQIGPE CFELLKVLGK GGYGKVFQVR KVTGAASGKI
110 120 130 140 150
FAMKVLKKAM IVRNAKDTAH TKAERNILEE VKHPFIVDLI YAFQTGGKLY
160 170 180 190 200
LILEYLSGGE LFMQLEREGI FMEDTACFYL AEISMALGHL HQKGIIYRDL
210 220 230 240 250
KPENIMLNNN GHVKLTDFGL CKESIHDGTY THTFCGTIEY MAPEILMRSG
260 270 280 290 300
HNRAVDWWSL GALMYDMLTG APPFTGENRK KTIDKILKCK LSLPPYLTYE
310 320 330 340 350
ARELLKKLLR RNASTRLGGG SGDSAEVQAD PFFRFINWDD LLARKVEPPF
360 370 380 390 400
KPFLQSADDV SQFDSKFTSQ TPVDSPDDST LSESANQVFL GFTYVAPSVL
410 420 430 440 450
ENLKEKFSFE PKVRSPRKFP GSPRTPVSPV KFARGDCWPH GPPLTDAPAL
460 470 480 490 500
LSLSSSGDQP MEVSTPEQMD MSSGFTTETS APLPIRHPSG LHAGSYKKQA
510
YPLNSRRPEH LRMNL
Length:515
Mass (Da):57,479
Last modified:May 1, 2013 - v1
Checksum:i2B8838CAE80BA8A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGAJ01033120 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSXMAT00000000142; ENSXMAP00000000142; ENSXMAG00000000125

Similar proteinsi

Entry informationi

Entry nameiM3ZD50_XIPMA
AccessioniPrimary (citable) accession number: M3ZD50
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: June 20, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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