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Protein

RNA helicase

Gene

DDX31

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase, RNA-bindingSAAS annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA helicaseSAAS annotation (EC:3.6.4.13SAAS annotation)
Gene namesi
Name:DDX31Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Sequence similaritiesi

Belongs to the DEAD box helicase family.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000075041
KOiK14806
OMAiDQKMIVF

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR025313 DUF4217
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF13959 DUF4217, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM01178 DUF4217, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

M3Z985-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPDLASQRH SESFPSVNSR PNVILPGREG RREGLPPGRG TRGSLVPTRP
60 70 80 90 100
VPPSPAPLGA GPYSWSRSGP GRGGGAGSSR VPRGVPGPAV CAPGSLLHHA
110 120 130 140 150
SPTQAMAAAD GSLLDNPRTF SRRPPAQASR QAKATKRKYQ ASRDAPPAKR
160 170 180 190 200
RNETSFLPAK KTSVKETQRT FKGNTQKTFS PKKHSVSTSD RNQEERQCIK
210 220 230 240 250
TSSLFKNNPD IPELHRPVVK QVQEKVFTSA AFHELGLHPH LISTINTVLK
260 270 280 290 300
MSSMTSVQKQ SIPVLLEGRD ALVRSQTGSG KTLAYCIPVV QSLQAMESKI
310 320 330 340 350
QRSDGPYALV LVPTRELALQ SFDTVQKLLK PFMWIVPGVL MGGEKRKSEK
360 370 380 390 400
ARLRKGINIL ISTPGRLVDH IKSTKNIHFS RLRWLVFDEA DRILDLGFEK
410 420 430 440 450
DITVILNAVN AECQKRQNVL LSATLTEGVT RLADISLHDP VSISVLDKSH
460 470 480 490 500
DQLNPKDKAV QEVCPPPAGD ELDSFAIPES LEQHVTVVPS KLRLVCLAAF
510 520 530 540 550
ILQKCKFEKD QKMVVFFSSC ELVEFHYSLF LQTLLSSSGA PASGQLPSAS
560 570 580 590 600
TRLKFLRLHG SMEQEERTAV FQEFSRSRRG VLLCTDVAAR GLDLPQVTWI
610 620 630 640 650
VQYSAPSSPA EYIHRIGRTA RIGCHGSSLL ILAPSEAEYV NSLASHKINV
660 670 680 690 700
SEIKMEDILC VLTRDDCFKG KRWGAQKSHA VGPQEIRERA TVLQTVFEDY
710 720 730 740 750
VHSSERRVSW AKKALQSFIQ AYATYPRELK HIFHVRSLHL GHVAKSFGLR
760 770 780 790 800
DAPRNLSALT RRKRKAHLKR PDLHKKTQSK HSLAEILRSE YSSGMEADVA
810 820 830 840 850
KVKKQNAPGE PGGRPLLHSL QPTPCFGRGK TLKWRKTQKG LQRDSQTSQK

V
Length:851
Mass (Da):94,167
Last modified:February 28, 2018 - v2
Checksum:i029085C4AAA75EB3
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G1RR00G1RR00_NOMLE
Uncharacterized protein
DDX31
585Annotation score:
A0A2I3GQY1A0A2I3GQY1_NOMLE
Uncharacterized protein
DDX31
320Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01097544 Genomic DNA No translation available.
ADFV01097545 Genomic DNA No translation available.
ADFV01097546 Genomic DNA No translation available.
ADFV01097547 Genomic DNA No translation available.
RefSeqiXP_003276832.1, XM_003276784.3

Genome annotation databases

EnsembliENSNLET00000031805; ENSNLEP00000023272; ENSNLEG00000012870
GeneIDi100585793
KEGGinle:100585793

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01097544 Genomic DNA No translation available.
ADFV01097545 Genomic DNA No translation available.
ADFV01097546 Genomic DNA No translation available.
ADFV01097547 Genomic DNA No translation available.
RefSeqiXP_003276832.1, XM_003276784.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSNLET00000031805; ENSNLEP00000023272; ENSNLEG00000012870
GeneIDi100585793
KEGGinle:100585793

Organism-specific databases

CTDi64794

Phylogenomic databases

GeneTreeiENSGT00550000075041
KOiK14806
OMAiDQKMIVF

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR025313 DUF4217
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF13959 DUF4217, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM01178 DUF4217, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3Z985_NOMLE
AccessioniPrimary (citable) accession number: M3Z985
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 36 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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