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Entry version 45 (02 Jun 2021)
Sequence version 1 (01 May 2013)
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Protein
Submitted name:

Rap associating with DIL domain

Gene

RADIL

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesionARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Rap associating with DIL domainImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RADILImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000715 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9668.ENSMPUP00000016550

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini61 – 164Ras-associatingInterPro annotationAdd BLAST104
Domaini494 – 760DiluteInterPro annotationAdd BLAST267
Domaini951 – 1036PDZInterPro annotationAdd BLAST86

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni187 – 232DisorderedSequence analysisAdd BLAST46
Regioni810 – 941DisorderedSequence analysisAdd BLAST132

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi211 – 228Polar residuesSequence analysisAdd BLAST18
Compositional biasi810 – 836Polar residuesSequence analysisAdd BLAST27

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0160, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159293

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010386_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3YYZ0

Identification of Orthologs from Complete Genome Data

More...
OMAi
LYVRHFL

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00060, FHA, 1 hit
cd15472, Myo5p-like_CBD_Rasip1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037983, CBD_Rasip1/Radil
IPR002710, Dilute_dom
IPR000253, FHA_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR000159, RA_dom
IPR008984, SMAD_FHA_dom_sf
IPR029071, Ubiquitin-like_domsf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01843, DIL, 1 hit
PF00595, PDZ, 1 hit
PF00788, RA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01132, DIL, 1 hit
SM00228, PDZ, 1 hit
SM00314, RA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49879, SSF49879, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51126, DILUTE, 1 hit
PS50106, PDZ, 1 hit
PS50200, RA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M3YYZ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFYGAHFIMS PPTKSKLKRQ SQLLSSMLSR TLSYKYRDLD TTFSSLGASD
60 70 80 90 100
DPAELSTQLS APGVLKVFGD SVCTGTHYKS VLATCMSSAQ ELVKEALERY
110 120 130 140 150
ALSPECASQY VLCDVVGQAG GSGQQWQAEC FRVFGDNEKP LLIQELWKPR
160 170 180 190 200
EGLSRRFELR KKSDVEELAA KDVDTMTAGI NAQARRLQRH RAKGTPVLAP
210 220 230 240 250
GGARSPPTPR LRRTVSESSL SSAATQGPEE RARDTMRFSL YESPHLLLLQ
260 270 280 290 300
GYSQQHDSLV YLLNREQHTV GQRTPSSKPS VSLSAPDILP LHCTIRRHQT
310 320 330 340 350
PGPEPAASRL VLEPIPGAPV SVNFAEVGGR AVVLRHGDLL SLGLYYLLLF
360 370 380 390 400
KDPAQAQPLP AQALARLRAI PRSCGLCGAA LRARGASASG SAPATLPRPR
410 420 430 440 450
LLHLEFEPEV EDALLQRILT LVEPGGDDHK LAPAFLLCLC IQHSATRLEP
460 470 480 490 500
GSFGQLLLKI AKAIRETVWE KTKELAEKQA QLQEPLSLAS FPMAGLVPDL
510 520 530 540 550
QHILFWMSNS VELLYFIQQK CPLYMQSLEE ELDVTGSRES LFSCALTASE
560 570 580 590 600
EAMAALEEVI LHAFQQCVYY VSKSLYVCLP ALLECPPFQT ERRESWCSAP
610 620 630 640 650
QLPEELRHVV SVYQATMDLL RQFRVHPEIA SQVLAYLFFF SSTLLFNQLL
660 670 680 690 700
DKGPSLSCFH WPRGVQACAR LQQLLEWMRS AGHGEAGERF FRKLSCTLNL
710 720 730 740 750
LATPRAQLIQ MSWANLRAAF PTLSPAQLHR LLTQYQLASA VGPMSAWEPG
760 770 780 790 800
AQDSPEAFKS EEVLESYENP PPIVLPSEGF QVDLEADCLD DSIYQHLLYI
810 820 830 840 850
RHFLWSLRSK PSPSGGSSQS GGLEGPHHTT SEGQSGPLVC RGAREAGQGR
860 870 880 890 900
PLASAGAPRA GGLSGRQSRG GPQAGPLHVD SSCLLTPPST PLSLEPTGPD
910 920 930 940 950
WPEPRGTCGK VLLEGRRNAA PGGDSVGPAD EPPAAPSSRS SSTEDFCYVF
960 970 980 990 1000
VVELERGPSG LGMGLIDGLH TPLGAPGLYI QTLLPGSPAA SDGRLSLGDR
1010 1020 1030 1040 1050
ILEVNGSSLA GVSYLRAVNL IRNGGKKMRF LVAKSDVETA KKIRFRTPPS
Length:1,050
Mass (Da):114,344
Last modified:May 1, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B2C79930E3D4922
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEYP01085203 Genomic DNA No translation available.
AEYP01085204 Genomic DNA No translation available.
AEYP01085205 Genomic DNA No translation available.
AEYP01085206 Genomic DNA No translation available.
AEYP01085207 Genomic DNA No translation available.
AEYP01085208 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_012902562.1, XM_013047108.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMPUT00000016796; ENSMPUP00000016550; ENSMPUG00000016653

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101689781

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01085203 Genomic DNA No translation available.
AEYP01085204 Genomic DNA No translation available.
AEYP01085205 Genomic DNA No translation available.
AEYP01085206 Genomic DNA No translation available.
AEYP01085207 Genomic DNA No translation available.
AEYP01085208 Genomic DNA No translation available.
RefSeqiXP_012902562.1, XM_013047108.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9668.ENSMPUP00000016550

Genome annotation databases

EnsembliENSMPUT00000016796; ENSMPUP00000016550; ENSMPUG00000016653
GeneIDi101689781

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55698

Phylogenomic databases

eggNOGiKOG0160, Eukaryota
GeneTreeiENSGT00940000159293
HOGENOMiCLU_010386_0_0_1
InParanoidiM3YYZ0
OMAiLYVRHFL

Family and domain databases

CDDicd00060, FHA, 1 hit
cd15472, Myo5p-like_CBD_Rasip1, 1 hit
Gene3Di2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR037983, CBD_Rasip1/Radil
IPR002710, Dilute_dom
IPR000253, FHA_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR000159, RA_dom
IPR008984, SMAD_FHA_dom_sf
IPR029071, Ubiquitin-like_domsf
PfamiView protein in Pfam
PF01843, DIL, 1 hit
PF00595, PDZ, 1 hit
PF00788, RA, 1 hit
SMARTiView protein in SMART
SM01132, DIL, 1 hit
SM00228, PDZ, 1 hit
SM00314, RA, 1 hit
SUPFAMiSSF49879, SSF49879, 1 hit
SSF50156, SSF50156, 1 hit
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS51126, DILUTE, 1 hit
PS50106, PDZ, 1 hit
PS50200, RA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3YYZ0_MUSPF
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3YYZ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: June 2, 2021
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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