UniProtKB - M3YUL3 (M3YUL3_MUSPF)
Protein
Submitted name:
Kruppel like factor 10
Gene
KLF10
Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Functioni
GO - Molecular functioni
- core promoter sequence-specific DNA binding Source: Ensembl
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
GO - Biological processi
- bone mineralization Source: Ensembl
- cellular response to starvation Source: Ensembl
- circadian rhythm Source: Ensembl
- negative regulation of transcription, DNA-templated Source: Ensembl
- positive regulation of osteoclast differentiation Source: Ensembl
- somatic stem cell population maintenance Source: Ensembl
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Kruppel like factor 10Imported |
Gene namesi | Name:KLF10Imported |
Organismi | Mustela putorius furo (European domestic ferret) (Mustela furo)Imported |
Taxonomic identifieri | 9669 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Mustelidae › Mustelinae › Mustela › |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleus Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 369 – 398 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 399 – 428 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 429 – 456 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159405 |
HOGENOMi | CLU_046370_1_0_1 |
InParanoidi | M3YUL3 |
OMAi | QMVPLPT |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
M3YUL3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLNFGASLQQ AAEERMEMIS ERSKETLFSW NKTTEKSDFE AVEALMSMSC
60 70 80 90 100
SWKSDFKKYI ENRPVTPVSD MSEEENLLPG TPDFHTIPAF CLTPPYSPSD
110 120 130 140 150
FEPSQVSNLM ASAPSTGHFK SFSDAAKPHI AAPFKDEDKS PVSAPKLPKA
160 170 180 190 200
QATSVIRHTA DAQLCNHRSC PVKAASVLNY QDNSFRRRTH VTVEATRKNI
210 220 230 240 250
PCAAVSPNRS KCERNTAADV DEKASPALYD FSVPSSETVI CRPQPAPVSP
260 270 280 290 300
QQKSVLVSPP AVSTGGVPPM PVICQMVPLP ANNPVVTTVV PSTPPSQPPA
310 320 330 340 350
VCPPVVFMGT QVPKGAVMFV VPQPVVQNPK PPVVSPNGTR LSPIAPAPGF
360 370 380 390 400
SPSAAKVTPQ MDSSRIRSHI CSHPGCGKTY FKSSHLKAHM RTHTGEKPFS
410 420 430 440 450
CSWKGCERRF ARSDELSRHR RTHTGEKKFA CPMCDRRFMR SDHLTKHARR
460 470 480
HLSAKKLPNW QMEVSKLNDI ALPPTPAPTQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEYP01071254 Genomic DNA No translation available. AEYP01071255 Genomic DNA No translation available. |
RefSeqi | XP_004768930.1, XM_004768873.2 |
Genome annotation databases
Ensembli | ENSMPUT00000015260; ENSMPUP00000015023; ENSMPUG00000015132 |
GeneIDi | 101683627 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEYP01071254 Genomic DNA No translation available. AEYP01071255 Genomic DNA No translation available. |
RefSeqi | XP_004768930.1, XM_004768873.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9668.ENSMPUP00000015023 |
Genome annotation databases
Ensembli | ENSMPUT00000015260; ENSMPUP00000015023; ENSMPUG00000015132 |
GeneIDi | 101683627 |
Organism-specific databases
CTDi | 7071 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159405 |
HOGENOMi | CLU_046370_1_0_1 |
InParanoidi | M3YUL3 |
OMAi | QMVPLPT |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M3YUL3_MUSPF | |
Accessioni | M3YUL3Primary (citable) accession number: M3YUL3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2013 |
Last sequence update: | May 1, 2013 | |
Last modified: | August 12, 2020 | |
This is version 41 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |