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Protein

Putative hydroxypyruvate isomerase

Gene

HYI

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Proton donor/acceptorUniRule annotation1
Active sitei249Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:HYIImported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000013589

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 224AP_endonuc_2InterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
InParanoidiM3YQI0
OMAiCEYRPRA
OrthoDBiEOG091G0KZU

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

M3YQI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPLRFSANV SWLFPELPGL PARLRAAGGS GFKAAEVAWP YAEPPEALAR
60 70 80 90 100
AAREAGLRLV LINTPPGDRE KGEMGLGAVP GRQAAFREGL EQAVLYAKAL
110 120 130 140 150
GCPRIHLMAG RVPQGADRAA VRSEMETVFL ENLKHAAGVL AQESLVGLLE
160 170 180 190 200
PINTRITDPQ YFLDTPQQAA AILQKVGRPN LQLQMDLFHW QIMDGNLTGN
210 220 230 240 250
IREFLPLVGH VQVAQVPGRG EPNSPGELNF PYLFQLLEDE GYEGFVGCEY
260 270
QPQGDTAEGL SWLRAYWDRQ GHPQAGQ
Length:277
Mass (Da):30,240
Last modified:May 1, 2013 - v1
Checksum:i875380738501E061
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01007502 Genomic DNA No translation available.
RefSeqiXP_004740635.1, XM_004740578.2

Genome annotation databases

EnsembliENSMPUT00000013806; ENSMPUP00000013589; ENSMPUG00000013692
GeneIDi101671270

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01007502 Genomic DNA No translation available.
RefSeqiXP_004740635.1, XM_004740578.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000013589

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMPUT00000013806; ENSMPUP00000013589; ENSMPUG00000013692
GeneIDi101671270

Organism-specific databases

CTDi81888

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
InParanoidiM3YQI0
OMAiCEYRPRA
OrthoDBiEOG091G0KZU

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3YQI0_MUSPF
AccessioniPrimary (citable) accession number: M3YQI0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: March 28, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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