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Entry version 44 (02 Jun 2021)
Sequence version 1 (01 May 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi559 – 566ATPPROSITE-ProRule annotation8
Nucleotide bindingi1386 – 1393ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000715 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei24 – 44HelicalSequence analysisAdd BLAST21
Transmembranei251 – 279HelicalSequence analysisAdd BLAST29
Transmembranei300 – 328HelicalSequence analysisAdd BLAST29
Transmembranei340 – 359HelicalSequence analysisAdd BLAST20
Transmembranei366 – 387HelicalSequence analysisAdd BLAST22
Transmembranei399 – 417HelicalSequence analysisAdd BLAST19
Transmembranei444 – 465HelicalSequence analysisAdd BLAST22
Transmembranei905 – 923HelicalSequence analysisAdd BLAST19
Transmembranei1071 – 1092HelicalSequence analysisAdd BLAST22
Transmembranei1112 – 1137HelicalSequence analysisAdd BLAST26
Transmembranei1149 – 1174HelicalSequence analysisAdd BLAST26
Transmembranei1180 – 1200HelicalSequence analysisAdd BLAST21
Transmembranei1212 – 1233HelicalSequence analysisAdd BLAST22
Transmembranei1269 – 1291HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
M3YPZ2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9668.ENSMPUP00000013400

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini523 – 756ABC transporterInterPro annotationAdd BLAST234
Domaini1351 – 1584ABC transporterInterPro annotationAdd BLAST234

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili971 – 991Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0059, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164007

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000604_19_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3YPZ2

Identification of Orthologs from Complete Genome Data

More...
OMAi
IFYIRER

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR026082, ABCA
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR19229, PTHR19229, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00005, ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M3YPZ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLLWLNQFA VLLWKNFVLK KRKILSLVVE ICMTVVFSLL ILLYRSNTKK
60 70 80 90 100
TFQNVTVFRP LYLITPPDFI FKGDLEYELA YVPSTSDVVK NITETVKNTL
110 120 130 140 150
NINFTVRGFS SEAQFEKYVQ YEKKPTVRVV AAIVFDHDFK NSDDRLPLQV
160 170 180 190 200
KYHLRFGTGT ERTSDFLSSL VDTGWHTHIL FPEVPDIGPR NPLSNDGGDP
210 220 230 240 250
GYIREGFLLL QHIIDQAIIT YHNGEAAERM LNDATILLNR FPYPAYYMDS
260 270 280 290 300
FWYSFSALFP LIVILAFSLT ELTLIRTIVS EKEKRLKEYQ LMIGLNNAML
310 320 330 340 350
WASYFVSFFL MFLIIICLLC VILFVKIAPE VVIQYSDPSL VFVFFLCFVI
360 370 380 390 400
TSISFGFLIS TLFDTATLAV SVGGFLYFLT FFPYIFMQTI YTQMALTEKL
410 420 430 440 450
VFCLLSNVAV ALGANIISQM EMKQYGVQWD NIQSSVSPDD DLRFVHIMGM
460 470 480 490 500
LLFDAALFGL MAWYMDAVFP GRYGVPKPWY FFVQKSYWFG KALSVKYKED
510 520 530 540 550
KRIIDKIKSD YFEEEPVDLV AGIRIQHLYK EFTVEKDTIV AVKNLTFNVY
560 570 580 590 600
EGQITILLGP NGAGKTTTLS ILTGLTLPTS GKVYISGYDI SKDMVHIRNY
610 620 630 640 650
LGFCPQDDIL FSELTVSEHL YFYCVIKGVP PEIRATEVNN VLTSFDLLEK
660 670 680 690 700
RDALAQSLSG GMKRKLSIII ALIGGSKVVI LDEPTSGMDP VSRRFTWSVL
710 720 730 740 750
EQYRYDRTIL LTTHHMDEAD VLGDRIAIMV KGSLQCCGSS IFLKRIYGVG
760 770 780 790 800
YHIIVVKEPH CNVEEIIEVI DQHIPEARLE SDVAAELSFI LPKKYTHRFK
810 820 830 840 850
DLLTDLENRQ KELGISSFGV SITTMEEVFL RVIRKDEEAF QTPSLKEKNR
860 870 880 890 900
REDMNQNMNA SGSFERYSPT ASEHSNIRFN TGWSLHWQQF YAMFIKRAMF
910 920 930 940 950
SWRNWSLSLM QILGLLGIVY FLMKVEKISR NTIEPAREMD LEQYGQTTVL
960 970 980 990 1000
FSDDSHSDFS QNLTKILDIM LKAKKQKLQE VKGDLQTYLQ DSQECIYSCI
1010 1020 1030 1040 1050
IAISFRDQKV VTLWFNNMAY HSPPLSLAVL DNLIFMALSG PDASITVSNK
1060 1070 1080 1090 1100
PQPQNIVSKK LEGRKIPGQQ VALNLYLGVS IFVSGFCLLT VTERINKAKH
1110 1120 1130 1140 1150
IQFVSGVSAI NFWLSALLWD FMIYFIACCL LLVVFLLSGL DELTKNYRFL
1160 1170 1180 1190 1200
DTLIIFLLFG WSVIPFTYLI SFLFSSHTSA YIKLVMLNYF AGVFGIVLES
1210 1220 1230 1240 1250
VITTSGSGSE SLLLDSLMVL PIYNFGMSIS KYFNNQNTRL LCSSKDVPAF
1260 1270 1280 1290 1300
INCSKAITEM NVYGLEKDAI GKFLIAMAVL GFIFFVLIFL LETTSWKVKT
1310 1320 1330 1340 1350
FVFHYIFFGI YKKFNKEIVS TELSGESEDD DVQAERNRIL EQPQESLNFT
1360 1370 1380 1390 1400
VLIKELTKIY FTCPAVLAVR NISLGIQKKE CFGLLGLNGA GKTTTFKILT
1410 1420 1430 1440 1450
GEETATSGDV FIENLSITKN LLEVRSKMGY CPQFDALLDY MTAREIMVMY
1460 1470 1480 1490 1500
ARLWGVPETQ ITQYVNKLLQ SLNLELYADK FIYTYSGGNK RGLSNAIALM
1510 1520 1530 1540 1550
GKPSVIFLDE PSTGMDPMAR RLFWNTITRA RESGKVIIIT SHSMEECDAL
1560 1570 1580 1590 1600
CTRLAIMVKG KFRCLGSPQH LKNKFGSVYI LKVKLKMDTD ENELEDFKTY
1610 1620 1630 1640 1650
IATVFPGSEL KQENQGILNY YIPREDNGWG KVFGILEEVK EKFSLEDYSI
1660 1670
SQITLEQVFL SFASPENKGG D
Length:1,671
Mass (Da):190,515
Last modified:May 1, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5EA16B5775E8DC62
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEYP01099339 Genomic DNA No translation available.
AEYP01099340 Genomic DNA No translation available.
AEYP01099341 Genomic DNA No translation available.
AEYP01099342 Genomic DNA No translation available.
AEYP01099343 Genomic DNA No translation available.
AEYP01099344 Genomic DNA No translation available.
AEYP01099345 Genomic DNA No translation available.
AEYP01099346 Genomic DNA No translation available.
AEYP01099347 Genomic DNA No translation available.
AEYP01099348 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_004780189.1, XM_004780132.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMPUT00000013615; ENSMPUP00000013400; ENSMPUG00000013502

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101694040

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01099339 Genomic DNA No translation available.
AEYP01099340 Genomic DNA No translation available.
AEYP01099341 Genomic DNA No translation available.
AEYP01099342 Genomic DNA No translation available.
AEYP01099343 Genomic DNA No translation available.
AEYP01099344 Genomic DNA No translation available.
AEYP01099345 Genomic DNA No translation available.
AEYP01099346 Genomic DNA No translation available.
AEYP01099347 Genomic DNA No translation available.
AEYP01099348 Genomic DNA No translation available.
RefSeqiXP_004780189.1, XM_004780132.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9668.ENSMPUP00000013400

PTM databases

SwissPalmiM3YPZ2

Genome annotation databases

EnsembliENSMPUT00000013615; ENSMPUP00000013400; ENSMPUG00000013502
GeneIDi101694040

Phylogenomic databases

eggNOGiKOG0059, Eukaryota
GeneTreeiENSGT00940000164007
HOGENOMiCLU_000604_19_1_1
InParanoidiM3YPZ2
OMAiIFYIRER

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR026082, ABCA
IPR027417, P-loop_NTPase
PANTHERiPTHR19229, PTHR19229, 1 hit
PfamiView protein in Pfam
PF00005, ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3YPZ2_MUSPF
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3YPZ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: June 2, 2021
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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