Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Pleckstrin and Sec7 domain containing 3

Gene

PSD3

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Pleckstrin and Sec7 domain containing 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PSD3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000715 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9669.ENSMPUP00000012786

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini782 – 967SEC7InterPro annotationAdd BLAST186
Domaini1018 – 1131PHInterPro annotationAdd BLAST114

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili631 – 651Sequence analysisAdd BLAST21
Coiled coili1159 – 1179Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0932 Eukaryota
COG5307 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156591

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3YN79

Identification of Orthologs from Complete Genome Data

More...
OMAi
EILWLQK

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0187

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00171 Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1000.11, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01369 Sec7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233 PH, 1 hit
SM00222 Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48425 SSF48425, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50190 SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M3YN79-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEQPEQQQM RTSFLFIQLQ APPAGALPSR STAAPGGPEE GHIFPGPRTG
60 70 80 90 100
LLAGRGLRRT QGLAAPPLRL LQKGGSGTEE PAAFSCSALK EEEREEKPQD
110 120 130 140 150
LDGRRGGVCR SPRHRPSLAT ASRKFGRLQP LSCSLPSPAP VMSDESSDSS
160 170 180 190 200
MGWEHWPAIS APQDLWSTDP WSWDALGCSV PQANLAHPTD RGESVTLKTA
210 220 230 240 250
VATCQVLPKS YEEGTGTTGR ARRARLYRYS PHIQTSQSYP APPATLPLKA
260 270 280 290 300
ETFVWVNNAS AHSQSVAKAK YEFLFGRSEE KPPDTSDHGG STLLPPNVTN
310 320 330 340 350
EFPEYGTMEE SGEGLRTSLG FDTESLPGGP QGQQGVQLFD DHHSGPDSVA
360 370 380 390 400
EGPKDVRESL SQSHLKEQSL QPIDSLISTL KATEARIASG TLQATKVLDK
410 420 430 440 450
DATSSFSVQQ VDKEQDTAPH KTKRQRANKS FPSGHEKGPD IPLSAEVTTE
460 470 480 490 500
ENSYLSIQKN LTVLLTGETQ AELSKVTDDG RKGALRVQEP ACPVSSLGSP
510 520 530 540 550
AVTHTSAGSV RFLRERRSDQ GSSTGRPGRV KHVEFQGVEI LWTGGEKRET
560 570 580 590 600
QQPVDFEIPL ERTTSPESRE FSRVPSHLIS SAGLYNSVGL TESVWDETWN
610 620 630 640 650
ASSENPGTGS GTFSPLPLVD SGEDEVFLKD NKEHLEKKPE LERDKERTHE
660 670 680 690 700
QEEHLRGGDD DILGPGYTED STDVYSSQFE TILDNTSLYY SAESLETLYS
710 720 730 740 750
EPDSYFSFEM PLTPMIQQRI KEGSQFLERT SVAGQQDVLS VSADGGIVMG
760 770 780 790 800
YSSGITNGLT DTSDSIYMKG MPEIAFWGSN AGVKTTLLEA HSDMGSTEIL
810 820 830 840 850
EKETSESLSN GTSSNIEAAK RLAKRLYQLD RFKRSDVAKH LGKNNEFSKL
860 870 880 890 900
VAEEYLKFFD FTGMTLDQSL RYFFKAFSLV GETQERERVL IHFSNRYFYC
910 920 930 940 950
NPNTIASQDG VHCLTCAMML LNTDLHGHNI GKKMTCQEFI ANLQGINEGG
960 970 980 990 1000
DFSKDLLKAL YNSIKNEKLE WAVDDEEKKK SPSEGTDEKA NGTHPKTISR
1010 1020 1030 1040 1050
IGSTTNPFLD IPHDPNAAVY KSGFLARKIH ADMDGKKTPR GKRGWKTFYA
1060 1070 1080 1090 1100
VLKGTVLYLQ KDEYKPEKAL SEEDLKNAVS VHHALASKAT DYEKKPNVLK
1110 1120 1130 1140 1150
LKTADWRVLL FQAQSPEEMQ GWINKINCVA AVFSAPPFPA AIGSQKKFSR
1160 1170 1180 1190 1200
PLLPATTTKL SQEEQLKSHE SKLKQITTEL AEHRSYPPDK KVKAKEIDEY
1210 1220 1230 1240 1250
RLKDHYLEFE KTRYEIYVSI LKGGGKELLS NNENEAAGLK KSHSSPSLNP
1260 1270 1280
DSSPVTAKVK RNVSERKDHR PETPSIKQKV T
Length:1,281
Mass (Da):141,355
Last modified:May 1, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E208DE6FA74AB8F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEYP01087717 Genomic DNA No translation available.
AEYP01087718 Genomic DNA No translation available.
AEYP01087719 Genomic DNA No translation available.
AEYP01087720 Genomic DNA No translation available.
AEYP01087721 Genomic DNA No translation available.
AEYP01087722 Genomic DNA No translation available.
AEYP01087723 Genomic DNA No translation available.
AEYP01087724 Genomic DNA No translation available.
AEYP01087725 Genomic DNA No translation available.
AEYP01087726 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_004775787.1, XM_004775730.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMPUT00000012993; ENSMPUP00000012786; ENSMPUG00000012884

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101694389

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01087717 Genomic DNA No translation available.
AEYP01087718 Genomic DNA No translation available.
AEYP01087719 Genomic DNA No translation available.
AEYP01087720 Genomic DNA No translation available.
AEYP01087721 Genomic DNA No translation available.
AEYP01087722 Genomic DNA No translation available.
AEYP01087723 Genomic DNA No translation available.
AEYP01087724 Genomic DNA No translation available.
AEYP01087725 Genomic DNA No translation available.
AEYP01087726 Genomic DNA No translation available.
RefSeqiXP_004775787.1, XM_004775730.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000012786

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMPUT00000012993; ENSMPUP00000012786; ENSMPUG00000012884
GeneIDi101694389

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23362

Phylogenomic databases

eggNOGiKOG0932 Eukaryota
COG5307 LUCA
GeneTreeiENSGT00940000156591
InParanoidiM3YN79
OMAiEILWLQK
OrthoDBiEOG091G0187

Family and domain databases

CDDicd00171 Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
PfamiView protein in Pfam
PF01369 Sec7, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00222 Sec7, 1 hit
SUPFAMiSSF48425 SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50190 SEC7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3YN79_MUSPF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3YN79
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: December 5, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again