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Entry version 41 (05 Jun 2019)
Sequence version 1 (01 May 2013)
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Protein
Submitted name:

Ankyrin 3

Gene

ANK3

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANK3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000715 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9668.ENSMPUP00000010946

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 815ANK_REP_REGIONInterPro annotationAdd BLAST776
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati73 – 105ANKPROSITE-ProRule annotationAdd BLAST33
Repeati106 – 138ANKPROSITE-ProRule annotationAdd BLAST33
Repeati139 – 171ANKPROSITE-ProRule annotationAdd BLAST33
Repeati172 – 195ANKPROSITE-ProRule annotationAdd BLAST24
Repeati234 – 266ANKPROSITE-ProRule annotationAdd BLAST33
Repeati267 – 299ANKPROSITE-ProRule annotationAdd BLAST33
Repeati300 – 332ANKPROSITE-ProRule annotationAdd BLAST33
Repeati333 – 365ANKPROSITE-ProRule annotationAdd BLAST33
Repeati366 – 398ANKPROSITE-ProRule annotationAdd BLAST33
Repeati399 – 431ANKPROSITE-ProRule annotationAdd BLAST33
Repeati432 – 464ANKPROSITE-ProRule annotationAdd BLAST33
Repeati465 – 497ANKPROSITE-ProRule annotationAdd BLAST33
Repeati498 – 530ANKPROSITE-ProRule annotationAdd BLAST33
Repeati531 – 563ANKPROSITE-ProRule annotationAdd BLAST33
Repeati564 – 596ANKPROSITE-ProRule annotationAdd BLAST33
Repeati597 – 629ANKPROSITE-ProRule annotationAdd BLAST33
Repeati630 – 662ANKPROSITE-ProRule annotationAdd BLAST33
Repeati663 – 695ANKPROSITE-ProRule annotationAdd BLAST33
Repeati696 – 728ANKPROSITE-ProRule annotationAdd BLAST33
Repeati729 – 761ANKPROSITE-ProRule annotationAdd BLAST33
Repeati762 – 794ANKPROSITE-ProRule annotationAdd BLAST33
Domaini973 – 1128ZU5InterPro annotationAdd BLAST156
Domaini1130 – 1277ZU5InterPro annotationAdd BLAST148
Domaini3637 – 3721DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 44DisorderedSequence analysisAdd BLAST44
Regioni1510 – 1531DisorderedSequence analysisAdd BLAST22
Regioni1601 – 1620DisorderedSequence analysisAdd BLAST20
Regioni1958 – 1978DisorderedSequence analysisAdd BLAST21
Regioni2061 – 2083DisorderedSequence analysisAdd BLAST23
Regioni2097 – 2151DisorderedSequence analysisAdd BLAST55
Regioni2163 – 2254DisorderedSequence analysisAdd BLAST92
Regioni2292 – 2313DisorderedSequence analysisAdd BLAST22
Regioni2368 – 2424DisorderedSequence analysisAdd BLAST57
Regioni2465 – 2499DisorderedSequence analysisAdd BLAST35
Regioni2583 – 2741DisorderedSequence analysisAdd BLAST159
Regioni2789 – 2811DisorderedSequence analysisAdd BLAST23
Regioni2930 – 2950DisorderedSequence analysisAdd BLAST21
Regioni2973 – 2998DisorderedSequence analysisAdd BLAST26
Regioni3025 – 3078DisorderedSequence analysisAdd BLAST54
Regioni3121 – 3267DisorderedSequence analysisAdd BLAST147
Regioni3280 – 3508DisorderedSequence analysisAdd BLAST229
Regioni3538 – 3600DisorderedSequence analysisAdd BLAST63
Regioni3784 – 3822DisorderedSequence analysisAdd BLAST39
Regioni3895 – 3923DisorderedSequence analysisAdd BLAST29
Regioni3974 – 4028DisorderedSequence analysisAdd BLAST55

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1602 – 1620PolarSequence analysisAdd BLAST19
Compositional biasi2103 – 2120PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2121 – 2137PolarSequence analysisAdd BLAST17
Compositional biasi2172 – 2192Pro-richSequence analysisAdd BLAST21
Compositional biasi2210 – 2239PolyampholyteSequence analysisAdd BLAST30
Compositional biasi2394 – 2424PolarSequence analysisAdd BLAST31
Compositional biasi2583 – 2609PolyampholyteSequence analysisAdd BLAST27
Compositional biasi2683 – 2712PolarSequence analysisAdd BLAST30
Compositional biasi2722 – 2740PolyampholyteSequence analysisAdd BLAST19
Compositional biasi3033 – 3050PolarSequence analysisAdd BLAST18
Compositional biasi3121 – 3177PolarSequence analysisAdd BLAST57
Compositional biasi3216 – 3234PolyampholyteSequence analysisAdd BLAST19
Compositional biasi3325 – 3349PolyampholyteSequence analysisAdd BLAST25
Compositional biasi3371 – 3399PolarSequence analysisAdd BLAST29
Compositional biasi3456 – 3489PolyampholyteSequence analysisAdd BLAST34
Compositional biasi3539 – 3563PolyampholyteSequence analysisAdd BLAST25
Compositional biasi3570 – 3593PolarSequence analysisAdd BLAST24
Compositional biasi3784 – 3798PolarSequence analysisAdd BLAST15
Compositional biasi3988 – 4002PolyampholyteSequence analysisAdd BLAST15
Compositional biasi4009 – 4028PolyampholyteSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154939

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
M3YHY9

Identification of Orthologs from Complete Genome Data

More...
OMAi
QSPEDDW

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 2 hits
PF12796 Ank_2, 6 hits
PF13606 Ank_3, 1 hit
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M3YHY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHAASQLKK NRDLEINAEE ETEKKRKHRK RSRDRKKKSD ANASYLRAAR
60 70 80 90 100
AGHLEKALDY IKNGVDINIC NQNGLNALHL ASKEGHVEVV SELLQREANV
110 120 130 140 150
DAATKKGNTA LHIASLAGQA EVVKVLVTNG ANVNAQSQNG FTPLYMAAQE
160 170 180 190 200
NHLEVVKFLL DNGASQSLAT EDGFTPLAVA LQQGHDQVVS LLLENDTKGK
210 220 230 240 250
VRLPALHIAA RKDDTKAAAL LLQNDNNADV ESKSGFTPLH IAAHYGNINV
260 270 280 290 300
ATLLLNRAAA VDFTARNDIT PLHVASKRGN ANMVKLLLDR GAKIDAKTRD
310 320 330 340 350
GLTPLHCGAR SGHEQVVEML LDRAAPILSK TKNGLSPLHM ATQGDHLNCV
360 370 380 390 400
QLLLQHNVPV DDVTNDYLTA LHVAAHCGHY KVAKVLLDKK ANPNAKALNG
410 420 430 440 450
FTPLHIACKK NRIKVMELLL KHGASIQAVT ESGLTPIHVA AFMGHVNIVS
460 470 480 490 500
QLMHHGASPN TTNVRGETAL HMAARSGQAE VVRYLVQDGA QVEAKAKDDQ
510 520 530 540 550
TPLHISARLG KADIVQQLLQ QGASPNAATT SGYTPLHLSA REGHEDVAAF
560 570 580 590 600
LLDHGASLSI TTKKGFTPLH VAAKYGKLEV ANLLLQKSAS PDAAGKSGLT
610 620 630 640 650
PLHVAAHYDN QKVALLLLDQ GASPHAAAKN GYTPLHIAAK KNQMDIATTL
660 670 680 690 700
LEYGADANAV TRQGIASVHL AAQEGHVDMV SLLLGRNANV NLSNKNGLTP
710 720 730 740 750
LHLAAQEDRV NVAEVLVNQG ANVDAQTKMG YTPLHVGCHY GNIKIVNFLL
760 770 780 790 800
QHSAKVNAKT KNGYTPLHQA AQQGHTHIIN VLLQNNASPN ELTVNGNTAL
810 820 830 840 850
AIARRLGYIS VVDTLKVVTE ETMTTTTIIE KHKMNVPETM NEVLDMSDDE
860 870 880 890 900
GEDAMTGDTD KYLGPQDLKE LGDDSLPAEG YMGFSLGARS ASPKISSDRS
910 920 930 940 950
YTLNRSSYAR DSMMIEELLV PSKEQHLTFT REFDSDSLRH YSWAADTLDN
960 970 980 990 1000
VNLVSSPVHS GYSSPLPQYD SRFLVSFMVD ARGGSMRGSR HHGMRIIIPP
1010 1020 1030 1040 1050
RKCTAPTRIT CRLVKRHKLA NPPPMVEGEG LASRLVEMGP AGAQFLGPVI
1060 1070 1080 1090 1100
VEIPHFGSMR GKERELIVLR SENGETWKEH QFDSKNEDLT ELLNGMDEEL
1110 1120 1130 1140 1150
DSPEELGKKR ICRIITKDFP QYFAVVSRIK QESNQIGPEG GILSSTTVPL
1160 1170 1180 1190 1200
VQASFPEGAL TKRIRVGLQA QPVPDEIVKK ILGNKATFSP IVTVEPRRRK
1210 1220 1230 1240 1250
FHKPITMTIP VPPPSGEGVA NGYKGDTTPN LRLLCSITGG TSPAQWEDIT
1260 1270 1280 1290 1300
GTTPLTFIKD CVSFTTNVSA RFWLADCHQV LETVGLATQL YRELICVPYM
1310 1320 1330 1340 1350
AKFVVFAKMN DPVESCLRCF CMTDDKVDKT LEQQENFEEV ARSKDIEVLE
1360 1370 1380 1390 1400
GKPIYVDCYG NLAPLTKGGQ QLVFNFYAFK ENRLPFSIKV RDTSQEPCGR
1410 1420 1430 1440 1450
LSFLKEPKTT KGLPQTAVCN LNITLPAHKK ETESDQDDEA EKADRRQSFA
1460 1470 1480 1490 1500
SLALRKRYSY LTEPGMKTVE RSAGATRSLP TTYSYKPFFS TRPYQSWTTA
1510 1520 1530 1540 1550
PVTVPGPAKS GFTSLSSSSS NTPSASPLKS IWSVSTPSPI KSTLGASTTS
1560 1570 1580 1590 1600
SVKSISDVAS PIRSFRTMSS PIKTVVSQSP YNIQVSSGNL VRAPTVPEAS
1610 1620 1630 1640 1650
PLKGLASSST FSSRTSPVTT AGSLLERSSI TMTPPASPKS NINMYSSSLP
1660 1670 1680 1690 1700
FKSIITSAAP LISSPLKSVV SPAKSAVDVI SSAKVTMASS LSSPVKQMPG
1710 1720 1730 1740 1750
HAEVALVNGS ISPLKYPSSS MLINGCKATA TLQEKISTAT NSVSSVVNAT
1760 1770 1780 1790 1800
TDTVEKVFST TTAMPFSPLR SYVSSTPSAF QSLRTPSASA LYTSLGSSIS
1810 1820 1830 1840 1850
ATTSSVTSSI ITVPVYSVVN VLPEPALKKL PDSSSLTKSA AALLSPIKTL
1860 1870 1880 1890 1900
TTETRPQPHF NRTSSPVKSS LFLAPSALKL STPSSLSSSQ EILKDVAEMK
1910 1920 1930 1940 1950
EDLMRMTAIL QTDVPEEKPF QPELPKEGRI DDEEPFKIVE KVKEDLVKVS
1960 1970 1980 1990 2000
EILKKDVCVD NKGPPKSPKS DKGLSPEDDW IEFSSEEIRE ARQQAAASHS
2010 2020 2030 2040 2050
PSLPERVQVK AKAASEKDYN LTKVIDYLTN DIGSSSLTNL KYKFEDAKKD
2060 2070 2080 2090 2100
GEERQKRILK PAIALQEHKL KMPPASMRPS TSEKELCKMA DSFFGTDTIL
2110 2120 2130 2140 2150
ESPDDFSQHD QDKSPLSDSG FETRSEKTPS APQSAESTGP KPLFHEVPIP
2160 2170 2180 2190 2200
PVITETRTEV VHVIRSYEPS AGDAPPGPPE EPVSPKPSPT FTELEPKPTT
2210 2220 2230 2240 2250
SSIKEKVKAF QMKANGDDDD HSRVLSKGMR VKEETHITTT TRMVYHSPPG
2260 2270 2280 2290 2300
SEGASERIEE TMSVHDIMKA FQSGRDPSKE LAGLFEHKSA VPPDVHKSAA
2310 2320 2330 2340 2350
ETPAQHAEKD NQMKPKLERI IEVHIEKGNQ AEPTEVIIRE TKKHPEKEMY
2360 2370 2380 2390 2400
VYQKDLSRGD INLKDFLPEK HDAFPCPEEQ GQQEEEELTA EESLPSYLES
2410 2420 2430 2440 2450
SRVNTPVSQE EDSRPSSAQL ISDDSYKTLK LLSQHSIEYH DDELSELRGE
2460 2470 2480 2490 2500
SYRFAEKMLL SEKLDVSHSD TEESVTDHAG PPSSELQGSD KRSREKVVTA
2510 2520 2530 2540 2550
PKKEILSKIY KDVSENGVGK VSKDEHFDKV TVLHCSGDVS SPKHAMWMRF
2560 2570 2580 2590 2600
TEDRLDRGRE KLIYEDRVDR TVKEAEEKLT EVSQFFRDKT EKLNDELQSP
2610 2620 2630 2640 2650
EKKPRPRNGK EYSSQSSPGS SPEKVLLTEL VASSDEWVKA RQHGPDGPGV
2660 2670 2680 2690 2700
PTADEQKAAS PPSSPEKKVL SPQPDDSKPT EETQESVSQS KAPAGPQSGF
2710 2720 2730 2740 2750
QLKQSKLSSI RLKFEQGAQA KSKDVSQEER KPEGQSRIPV KKIQESKLPV
2760 2770 2780 2790 2800
YQVFAREKQL KAVDLSDERG SAQNDLMVLK AKDEHAQSGE LVVNDAGSED
2810 2820 2830 2840 2850
VKTQRTEMSS KAMPDYFSEQ QAKDLACHVT SDVATKGPWD KKVFRTWESS
2860 2870 2880 2890 2900
GATNNKSQKE KLSHVLVHNV RENHVGHPDS KIVGQRHEFM SVTEREHKLL
2910 2920 2930 2940 2950
TNGSLSEIKE MTVKSPSKKV LYREYVVKEG GRPGGPLEQA PRRSESSAVS
2960 2970 2980 2990 3000
HIPVRAAEGR RMLSSDIPDG FCEQSTFPQQ ELSQKLPRSS MSKETVETQH
3010 3020 3030 3040 3050
FNSIEDEKIT YSEISKVSKR QSYVGLCPPL DETETSPTKS PDSLEFSPGK
3060 3070 3080 3090 3100
ESPSSDVFDH SPLDGLERVS PLAQTEGGKD IKTLPVYVSF VQVGKQYEKE
3110 3120 3130 3140 3150
IQQGSIKKII SQECKTVQET RGTFYTTRQQ KQPPSPQGSP EDDTLEQVSF
3160 3170 3180 3190 3200
LDSSGKSPLT PETPSSEEVS YEFTSKTPDS LIAYIPGKPS PIPEVSEESE
3210 3220 3230 3240 3250
EEEQAKSASL KQTTVEEVTV DRETPTDVSK DSNQRPKSNR VAYIEFPPPP
3260 3270 3280 3290 3300
PLDADQMEPD KKPHYLPERE ADMIEVSLRD EHDKYQLAEP VIRVQPPSPV
3310 3320 3330 3340 3350
PPGADVSDSS DDESLYQPVP VKKYTFKLKE VDDEQKEMTK SKAPADKPSS
3360 3370 3380 3390 3400
QKELETNGSG KDHEFGLGLD SPQNETAQNG NNDQSVTECS IATTAEFSHD
3410 3420 3430 3440 3450
TDATEIDSLD GYDLQDEDDG LTESDSKLPS QTMEIKKDVW NTEGILKPAD
3460 3470 3480 3490 3500
RSFSQSKLEV IEEEGRVGPD EDKPPSKSSS SEKTPDKTEQ KSGAQFFTLE
3510 3520 3530 3540 3550
GRHPDRSVFP DTYFSYKVDE EFATPFKTVA TKGLDFDPWS NNRGDDEVFD
3560 3570 3580 3590 3600
GKSREDETKP FGLAVEDRSP ATTPDTTPAR TPTDESTPTS EPNPFPFHEG
3610 3620 3630 3640 3650
KMFEMTRSGA IDMSKRDFVE ERLQFFQIGP QSPCERTDIR MAIVADHLGL
3660 3670 3680 3690 3700
SWTELARELN FSVDEINQIR VENPNSLISQ SFMLLKKWVT RDGKNATTDA
3710 3720 3730 3740 3750
LTSVLTKINR IDIVTLLEGP IFDYGNISGT RSFADENNVF HDPVDGYSSL
3760 3770 3780 3790 3800
QVELETPTGL HYTPPTPFQQ DDYFSDISSI ESPLRTPSRL SDGLVPSQGN
3810 3820 3830 3840 3850
IEHSADGPPV VTAEDTSLED SKLEDSMPLT EMPDAVDVDE SHLENVCLSW
3860 3870 3880 3890 3900
QNETSSGNLE SPAQARRITG GLLERLDDSP DQCRDSITSY LKGEPGKFEA
3910 3920 3930 3940 3950
NGSHAEVTPE AKTKSYFPES QNDIGKQSVK ETLKPKIHGS ARVEEPASSL
3960 3970 3980 3990 4000
TAYQKALEET SKFVIEEPKP CVPVSMKKMS RTPPADGKPR LNVHEEEGSS
4010 4020
GSEQKQGEGY KVKTTKKEIR NVEKKSHS
Length:4,028
Mass (Da):442,096
Last modified:May 1, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B3702175215972E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AEYP01063967 Genomic DNA No translation available.
AEYP01063968 Genomic DNA No translation available.
AEYP01063969 Genomic DNA No translation available.
AEYP01063970 Genomic DNA No translation available.
AEYP01063971 Genomic DNA No translation available.
AEYP01063972 Genomic DNA No translation available.
AEYP01063973 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMPUT00000011128; ENSMPUP00000010946; ENSMPUG00000011035

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01063967 Genomic DNA No translation available.
AEYP01063968 Genomic DNA No translation available.
AEYP01063969 Genomic DNA No translation available.
AEYP01063970 Genomic DNA No translation available.
AEYP01063971 Genomic DNA No translation available.
AEYP01063972 Genomic DNA No translation available.
AEYP01063973 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Protein-protein interaction databases

STRINGi9668.ENSMPUP00000010946

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMPUT00000011128; ENSMPUP00000010946; ENSMPUG00000011035

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000154939
InParanoidiM3YHY9
OMAiQSPEDDW

Family and domain databases

CDDicd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF00023 Ank, 2 hits
PF12796 Ank_2, 6 hits
PF13606 Ank_3, 1 hit
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3YHY9_MUSPF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3YHY9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: June 5, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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