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Protein

V-type proton ATPase subunit H

Gene

ATP6V1H

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit HUniRule annotation
Gene namesi
Name:ATP6V1HImported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Subcellular locationi

Interactioni

Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.UniRule annotation

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000010568

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini349 – 464V-ATPase_H_CInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the V-ATPase H subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2759 Eukaryota
COG5231 LUCA
GeneTreeiENSGT00390000003289
InParanoidiM3YGW1
OMAiRPIPWDG
OrthoDBiEOG091G0NQW

Family and domain databases

Gene3Di1.25.10.10, 1 hit
1.25.40.150, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR004908 ATPase_V1-cplx_hsu
IPR011987 ATPase_V1-cplx_hsu_C
IPR038497 ATPase_V1-cplx_hsu_C_sf
PANTHERiPTHR10698 PTHR10698, 1 hit
PfamiView protein in Pfam
PF11698 V-ATPase_H_C, 1 hit
PIRSFiPIRSF032184 ATPase_V1_H, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

M3YGW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKMDIRGAV DAAVPTNIIA AKAAEVRANK VNWQSYLQGQ MISAEDCEFI
60 70 80 90 100
QRFEMKRSPE EKQEMLQTEG SQCAKTFINL MTHISKEQTV QYILTMVDDM
110 120 130 140 150
LQENHQRVSI FFDYAKRSKN TAWSYFLPML NRQDLFTVHM AARIIAKLAA
160 170 180 190 200
WGKELMEGSD LNYYFNWIKT QLSSQKLRGS GVAVETGTVS SSDSSQYVQC
210 220 230 240 250
VAGCLQLMLR VNEYRFAWVE ADGVNCIMGV LSNKCGFQLQ YQMIFSIWLL
260 270 280 290 300
AFSPQMCEHL RRYNIIPVLS DILQESVKEK VTRIILAAFR NFLEKSTERE
310 320 330 340 350
TRQEYALAMI QCKVLKQLEN LEQQKYDDED ISEDIKFLLE KLGESVQDLS
360 370 380 390 400
SFDEYSSELK SGRLEWSPVH KSEKFWRENA VRLNEKNYEL LKILTKLLEV
410 420 430 440 450
SDDPQVLAVA AHDVGEYVRH YPRGKRVIEQ LGGKQLVMNH MHHEDQQVRY
460 470 480
NALLAVQKLM VHNWEYLGKQ LQSEQPQTAA ARS
Length:483
Mass (Da):55,898
Last modified:May 1, 2013 - v1
Checksum:i21CE24AE26C23E07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01070908 Genomic DNA No translation available.
AEYP01070909 Genomic DNA No translation available.
AEYP01070910 Genomic DNA No translation available.
AEYP01070911 Genomic DNA No translation available.
AEYP01070912 Genomic DNA No translation available.
AEYP01070913 Genomic DNA No translation available.
AEYP01070914 Genomic DNA No translation available.
RefSeqiXP_004768878.1, XM_004768821.2
XP_004768879.1, XM_004768822.2

Genome annotation databases

EnsembliENSMPUT00000010738; ENSMPUP00000010568; ENSMPUG00000010647
GeneIDi101686046

Similar proteinsi

Entry informationi

Entry nameiM3YGW1_MUSPF
AccessioniPrimary (citable) accession number: M3YGW1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: April 25, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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