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Protein
Submitted name:

Uncharacterized protein

Gene

TBC1D8B

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TBC1D8BImported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000003689

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini487 – 674Rab-GAP TBCInterPro annotationAdd BLAST188
Domaini858 – 893EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG4347 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00930000150890
InParanoidiM3XX89
OMAiQRECSKT
OrthoDBiEOG091G00RI

Family and domain databases

CDDicd13350 PH-GRAM1_TBC1D8B, 1 hit
cd13352 PH-GRAM2_TBC1D8B, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR036012 TBC1D8B_PH-GRAM1
IPR036015 TBC1D8B_PH-GRAM2
PfamiView protein in Pfam
PF02893 GRAM, 2 hits
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 2 hits
SM00164 TBC, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
PS50086 TBC_RABGAP, 1 hit

Sequencei

Sequence statusi: Complete.

M3XX89-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWLKPEEVLL KNALKLWLME RSNDYFVLQR RRGYGEEGGG GLTGLLVGTL
60 70 80 90 100
DSVLDSTAKV APFRILHQTP DSQVYLSIAC GANREEITKH WDWLEQNIMK
110 120 130 140 150
TLSVFDSNED ITNFVQGKIR GLIAEEGKHS FAKEDDPEKF REALLKFEKC
160 170 180 190 200
FGLPEQEKLV TYYSCSYWKG RVPCQGWLYL STNFLSFYSF LLGSEIKLII
210 220 230 240 250
SWDAVSKLEK TSNVILTESI HVCSQGENHY FSMFLHINET YLLMEQLANY
260 270 280 290 300
AIKRLFDKET FANDPILDDP LQITKRGLEI RAHSEQFGAF FRIPKEETLK
310 320 330 340 350
EVHECFLWVP FSHFNTHGKM CISENYICFA SQDGNQHSVI IPLREVLAID
360 370 380 390 400
KPNDSSKSVI ISIKGKTAFR FSEVKDFEQL VTKLRLKCGA ASSQYHDIST
410 420 430 440 450
EVSISSDSTD PSDNTEVQSL TCQRECSKTV NTEALMTVFH PQNLETLNSK
460 470 480 490 500
MLKEKMKEQS WNILFTECGR GVSMFRTKKT RDLVVRGIPE TLRGELWMLF
510 520 530 540 550
SGAVNDMAAN PGYYAEVVEQ SLGTCNLATE EIERDLRRSL PEHPAFQSDT
560 570 580 590 600
GISALRRVLT AYAYRNPKIG YCQAMNILTS VLLLYAKEEE AFWLLVAVCE
610 620 630 640 650
RMLPDYFNRR IIGALVDQAV FEELIRDHLP QLTEHMTDMT FFSSVSLSWF
660 670 680 690 700
LTLFISVLPI ESAVNVVDCF FYDGIKAILQ LGLAILDYNL DKLLTCKDDA
710 720 730 740 750
EAVTALNRFF DNVTNKDSPL PSSVQQGSNV SDEKSSHMKV DITDLIRESN
760 770 780 790 800
EKYGNIRYED IHSMRCRNRL YVIQTLEETT KQNVLRVVSQ DVKLSLHELD
810 820 830 840 850
ELYVIFKKEL FFSYYWCLSC PVLKYHDPSL PYLEQYQIDC QQFRVLYHLL
860 870 880 890 900
SPWAHSANKD SLALWTFRLL DENSDCLINF KEFSSAIDIM YNGSFTGKLK
910 920 930 940 950
LLFKLHIPPA YTEVNSKDPS QGDELSKEEL LYFSQLHVSK PTNVKEAESL
960 970 980 990 1000
KNSPEKGKGK VDIQAYLSQW QDELSKKEEN IKDLPRMNQS QFIQFSKTLY
1010 1020 1030 1040 1050
NLFHGDPEEE SLYQAIAVVT SLLLRMEEVG RKLHSPTASA KEFSGTVCAS
1060 1070 1080 1090 1100
GVPSEGKTES HLKKDPSSLR EEPQWSFAFE QILASLLNEP ALVRFFEKPI
1110 1120
DVKVKLENAK TSQLSCRTKM
Length:1,120
Mass (Da):128,326
Last modified:May 1, 2013 - v1
Checksum:iD0542CC06BB77021
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01071637 Genomic DNA No translation available.
AEYP01071638 Genomic DNA No translation available.
AEYP01071639 Genomic DNA No translation available.
RefSeqiXP_004769056.1, XM_004768999.2

Genome annotation databases

EnsembliENSMPUT00000003757; ENSMPUP00000003689; ENSMPUG00000003719
GeneIDi101671603

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01071637 Genomic DNA No translation available.
AEYP01071638 Genomic DNA No translation available.
AEYP01071639 Genomic DNA No translation available.
RefSeqiXP_004769056.1, XM_004768999.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000003689

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMPUT00000003757; ENSMPUP00000003689; ENSMPUG00000003719
GeneIDi101671603

Organism-specific databases

CTDi54885

Phylogenomic databases

eggNOGiKOG4347 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00930000150890
InParanoidiM3XX89
OMAiQRECSKT
OrthoDBiEOG091G00RI

Family and domain databases

CDDicd13350 PH-GRAM1_TBC1D8B, 1 hit
cd13352 PH-GRAM2_TBC1D8B, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR036012 TBC1D8B_PH-GRAM1
IPR036015 TBC1D8B_PH-GRAM2
PfamiView protein in Pfam
PF02893 GRAM, 2 hits
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 2 hits
SM00164 TBC, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
PS50086 TBC_RABGAP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3XX89_MUSPF
AccessioniPrimary (citable) accession number: M3XX89
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: November 7, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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