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Entry version 49 (02 Jun 2021)
Sequence version 3 (10 Oct 2018)
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Protein
Submitted name:

SH3 and multiple ankyrin repeat domains 2

Gene

SHANK2

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SH3 and multiple ankyrin repeat domains 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SHANK2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9685 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000011712 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome D1

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:81940, SHANK2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, SynapseARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

MethylationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSFCAG00000031477, Expressed in liver and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9685.ENSFCAP00000025425

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini182 – 383ANK_REP_REGIONInterPro annotationAdd BLAST202
Domaini525 – 584SH3InterPro annotationAdd BLAST60
Domaini625 – 719PDZInterPro annotationAdd BLAST95
Domaini1786 – 1849SAMInterPro annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 34DisorderedSequence analysisAdd BLAST34
Regioni447 – 482DisorderedSequence analysisAdd BLAST36
Regioni767 – 786DisorderedSequence analysisAdd BLAST20
Regioni877 – 906DisorderedSequence analysisAdd BLAST30
Regioni1012 – 1292DisorderedSequence analysisAdd BLAST281
Regioni1323 – 1371DisorderedSequence analysisAdd BLAST49
Regioni1434 – 1464DisorderedSequence analysisAdd BLAST31
Regioni1482 – 1526DisorderedSequence analysisAdd BLAST45
Regioni1574 – 1617DisorderedSequence analysisAdd BLAST44
Regioni1634 – 1672DisorderedSequence analysisAdd BLAST39
Regioni1684 – 1715DisorderedSequence analysisAdd BLAST32
Regioni1756 – 1776DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 23Polar residuesSequence analysisAdd BLAST23
Compositional biasi883 – 906Pro residuesSequence analysisAdd BLAST24
Compositional biasi1034 – 1071Polar residuesSequence analysisAdd BLAST38
Compositional biasi1271 – 1292Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi1323 – 1342Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi1503 – 1526Polar residuesSequence analysisAdd BLAST24
Compositional biasi1576 – 1592Pro residuesSequence analysisAdd BLAST17
Compositional biasi1684 – 1711Polar residuesSequence analysisAdd BLAST28
Compositional biasi1760 – 1776Polar residuesSequence analysisAdd BLAST17

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0504, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153561

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018169_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3XFL4

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
1.25.40.20, 2 hits
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR001660, SAM
IPR013761, SAM/pointed_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 2 hits
PF17820, PDZ_6, 1 hit
PF00536, SAM_1, 1 hit
PF07653, SH3_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 6 hits
SM00228, PDZ, 1 hit
SM00454, SAM, 1 hit
SM00326, SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769, SSF47769, 1 hit
SSF48403, SSF48403, 1 hit
SSF50044, SSF50044, 1 hit
SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 4 hits
PS50106, PDZ, 1 hit
PS50105, SAM_DOMAIN, 1 hit
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

M3XFL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRSPTSSED EMAQSFSDYS VGSESDSSKE ETIYDTIRAT AEKPSAPRME
60 70 80 90 100
ESQGHAVVIR ILIQDLQQTK CLRFDPDATV WVAKQRILCS LNQSLKDVLN
110 120 130 140 150
YGLFQPASSG RDGKFLDEER LLREYPQPAG QGIPSLEFRY KKRVYKPSNL
160 170 180 190 200
DEKQLAKLHT KTNLKKFTDH IQHRSVEKIT KMLERGLDPN FHDPDTGETP
210 220 230 240 250
LTLAAQLDDP AEVIKALRNG GAHLDFRARD GMTALHKAAR ARNQVALKTL
260 270 280 290 300
LELGASPDYK DSYGLTPLYH TAIVGGDPYC CELLLHEHAA VCCRDENGWH
310 320 330 340 350
EIHQACRYGH VQHLEHLLFY GADMAAQNAS GNTALHICAL YNQDSCARVL
360 370 380 390 400
LFRGGNKELK NYNSQTPFQV AIIAGNFELA EYIKNHKETD IVPFREAPAY
410 420 430 440 450
SNRRRRPPNT LAAPRVLLRS NSDNNLNTSA PDWAVCSATS HRSLSPQLLQ
460 470 480 490 500
QTPGKPEGAA RTLGGYTPGP YSRSPSLNRL GGALEDGKRL QRPWHVGPAF
510 520 530 540 550
PPGANKDTLS AFEYPEPKRK LYSAVPGRLF VVVKPYHPQV DGEIPLHRGD
560 570 580 590 600
RVKVLSIGEG GFWEGSARGH IGWFPAECVE EVQCRPKDSQ AETRADRSKK
610 620 630 640 650
LFRHYTVGSY DSFDGSSDCI IEEKTVVLQK KDNEGFGFVL RGAKADTPIE
660 670 680 690 700
EFTPTPAFPA LQYLESVDEG GVAWQAGLRT GDFLIEVNKE NVVKVGHRQV
710 720 730 740 750
VNMIRQGGNH LVLKVVTVTR NLDPDDTARK KAPPPPKRAP TTALTLRSKS
760 770 780 790 800
MTSELEELVD KASIRKKKDK PDEIVPASKP SRTADNVAVE SRVATIKQRP
810 820 830 840 850
TSRCFPSVSD MNSVYERQGI AVMTPTVPGS PKGPFLGLPR GTMRRQKSID
860 870 880 890 900
SRIFLSGITE EERQFLAPPM LKFTRSLSMP DTSEDIPPPP QSVPPSPPPP
910 920 930 940 950
SPTAYNCPKS PTPRVYGTIK PAFNQNAAAK VPPAARSDTV ATVMRDKGLY
960 970 980 990 1000
YRRELDRYSL DSEDLYSRSA AAQANFRSKR GQMPENPYSE VGRVASKAVY
1010 1020 1030 1040 1050
VPAKPARRKG MLVKQSNVED SPEKTCSIPI PTIIVKEPST SSSGKSSQGS
1060 1070 1080 1090 1100
STEIEPQASE QPGQLRPDDS LTVSSPFAAA IAGAVRDREK RLEARRNSPA
1110 1120 1130 1140 1150
FLSTDLGDED VGLGPPTPHV RSSNFPEEAD FGEEGGAEPL SLPAPGAAPR
1160 1170 1180 1190 1200
EPENHFAGGG EAAAQGEAGR PLNSTSKAKG PDGGPAVPPK GGSAAGPENY
1210 1220 1230 1240 1250
VHPLTGRLLD PSSPLALALS ARDRAMKESQ QGSKGEAPKA DLHKPLYIDT
1260 1270 1280 1290 1300
KMRPSVEAGF PPVTRQNTRG PLRRQETENK YETELGKDRK GEDKKNMLIN
1310 1320 1330 1340 1350
IVDTSQQRSA GLLMVHTVDA TKTDRLLEEE EEKADAEAKP DSLLSEVPEG
1360 1370 1380 1390 1400
APETEGALQI SASPEPAAAA PGRTIVAAGS VEEAVILPFR IPPPPLASVD
1410 1420 1430 1440 1450
LDEDFIFTEP LPPPLEFANS FDIPDDRIAS VPALTDLVKQ KKHDASQPPP
1460 1470 1480 1490 1500
LNPSQPANCA DSKKPAGLSN CLPASFLPPP ENFDAVTDSG IEEVDSRSSS
1510 1520 1530 1540 1550
DHHLETTSTV STVSSMSTLS SEGGDNVDTC TVYADGQAFT VDKPPVPPKP
1560 1570 1580 1590 1600
KVKPIIPKSN ALYQDALVEE DVDSFVIPPP APPPPPGSAQ PGAAKVTPPR
1610 1620 1630 1640 1650
TSKLWGDVSE VRSPIRSGPK ANVISELNSI LQQMNREKSA KPGEALDSPT
1660 1670 1680 1690 1700
GTKPASLAPR SPEVMSTVSG TRSTTVTFTV RPGTSQPITL QSRPTDFESR
1710 1720 1730 1740 1750
TSGTRRAPSP VVSPTEMNKE ILPAPLPAAA AVPSPTLSEV FSLPSQPPAG
1760 1770 1780 1790 1800
DLFGLNPAGR SRSPSPSILQ QPISNKPFTT KPVHLWTKPD VADWLESLNL
1810 1820 1830 1840
GEHKETFMDN EIDGSHLPNL QKEDLIDLGV TRVGHRMNIE RALKQLLDR
Length:1,849
Mass (Da):200,911
Last modified:October 10, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i163DB54A9ACA8621
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5F5XE81A0A5F5XE81_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,842Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5XUJ0A0A5F5XUJ0_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,764Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5XUN1A0A5F5XUN1_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,808Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5Y221A0A5F5Y221_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,812Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A337S3S8A0A337S3S8_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,523Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5XS53A0A5F5XS53_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,700Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M3W2T6M3W2T6_FELCA
SH3 and multiple ankyrin repeat dom...
SHANK2
1,205Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AANG04000779 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSFCAT00000023485; ENSFCAP00000025425; ENSFCAG00000004768

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04000779 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000025425

Genome annotation databases

EnsembliENSFCAT00000023485; ENSFCAP00000025425; ENSFCAG00000004768

Organism-specific databases

VGNCiVGNC:81940, SHANK2

Phylogenomic databases

eggNOGiKOG0504, Eukaryota
GeneTreeiENSGT00940000153561
HOGENOMiCLU_018169_0_0_1
InParanoidiM3XFL4

Gene expression databases

BgeeiENSFCAG00000031477, Expressed in liver and 9 other tissues

Family and domain databases

Gene3Di1.10.150.50, 1 hit
1.25.40.20, 2 hits
2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR001660, SAM
IPR013761, SAM/pointed_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
PfamiView protein in Pfam
PF12796, Ank_2, 2 hits
PF17820, PDZ_6, 1 hit
PF00536, SAM_1, 1 hit
PF07653, SH3_2, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 6 hits
SM00228, PDZ, 1 hit
SM00454, SAM, 1 hit
SM00326, SH3, 1 hit
SUPFAMiSSF47769, SSF47769, 1 hit
SSF48403, SSF48403, 1 hit
SSF50044, SSF50044, 1 hit
SSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 4 hits
PS50106, PDZ, 1 hit
PS50105, SAM_DOMAIN, 1 hit
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3XFL4_FELCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3XFL4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: October 10, 2018
Last modified: June 2, 2021
This is version 49 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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