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Protein

Protein transport protein sec16

Gene
N/A
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization.UniRule annotation

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein sec16UniRule annotation
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome F1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei596 – 616HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Golgi apparatusUniRule annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000014227 Expressed in 3 organ(s), highest expression level in liver

Interactioni

Subunit structurei

SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.UniRule annotation

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000013202

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini272 – 368Sec16InterPro annotationAdd BLAST97
Domaini437 – 588Sec16_CInterPro annotationAdd BLAST152

Sequence similaritiesi

Belongs to the SEC16 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1913 Eukaryota
ENOG4111J6D LUCA
GeneTreeiENSGT00530000063746
InParanoidiM3WKB6
KOiK20353
OrthoDBiEOG091G00RM

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit

Sequencei

Sequence statusi: Complete.

M3WKB6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFWAPQWPP QPWGRPTAPS KDPDRGLQRD GNHRPVPRSW YNGERYHQWQ
60 70 80 90 100
DTHRSPQPQQ DPRTDHQQPH YASRPGERRQ PVLGVDYYEG GYPRQLYSRP
110 120 130 140 150
GIEDPYQSYH SPTLREEYAY GDYYYHRPPQ QLQEERVPRR ESPYMWQEDH
160 170 180 190 200
RDQKYLSEHH HENQNSLSKS RNSHKDSPAS NTRPERPGDL FPESLLTGTQ
210 220 230 240 250
KNEPSLANES SLLRQHESGL SSSAYELSQY MGADSEPYDP VASAAWSPIQ
260 270 280 290 300
AEAVSAAGPK APMKFYISHV PVSFGPGGQL VRVGPSSPSD GQTALVELHS
310 320 330 340 350
MEIILSDSEE QEEMRTFSGP LIREDVHKVD IMTFCQQKAA QSRKSETQRS
360 370 380 390 400
RDSALLWQLL VLLCRQNGSM VGSDIAELLM QDCKKLEKYK RQPPVANLIN
410 420 430 440 450
LTDEDWPVLS SGTPNLLTGE IPPSVETPAQ IVEKFTKLLY YGRKKEALEW
460 470 480 490 500
AMKNHLWGHA LFLASKMDPR TYSWVMSGFT STLASNDPLQ TLFQFMSGRI
510 520 530 540 550
PQAATCCGDK QWGDWRPHLA VILSNQSGDL ELHQRTIVTM GDTLAGKGLV
560 570 580 590 600
EAAHFCYLVA HVPFGHYTVK TDHLALLGSS HREREGRFPG NCLREALLGL
610 620 630 640 650
MALLSIFLYA FHLVLLPSSG AVLHRSGQGG VPGGSRITSP GGLRPQPCSP
660 670 680 690
KLRVDLCGVL PPSDHLVAPW LHDQTSSLKN CQCDRSGWLE VLY
Length:693
Mass (Da):78,121
Last modified:October 10, 2018 - v3
Checksum:i04B58775A16902A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001043 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSFCAT00000014232; ENSFCAP00000013202; ENSFCAG00000014227
KEGGifca:101099013

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001043 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000013202

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000014232; ENSFCAP00000013202; ENSFCAG00000014227
KEGGifca:101099013

Organism-specific databases

CTDi89866

Phylogenomic databases

eggNOGiKOG1913 Eukaryota
ENOG4111J6D LUCA
GeneTreeiENSGT00530000063746
InParanoidiM3WKB6
KOiK20353
OrthoDBiEOG091G00RM

Gene expression databases

BgeeiENSFCAG00000014227 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3WKB6_FELCA
AccessioniPrimary (citable) accession number: M3WKB6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: October 10, 2018
Last modified: November 7, 2018
This is version 34 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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