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Entry version 47 (03 Jul 2019)
Sequence version 3 (10 Oct 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene

COL6A3

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COL6A3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9685 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000011712 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome C1

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:61068 COL6A3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501643857026 – 3178Sequence analysisAdd BLAST3153

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSFCAG00000012720 Expressed in 3 organ(s), highest expression level in liver

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9685.ENSFCAP00000011794

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 213VWFAInterPro annotationAdd BLAST175
Domaini242 – 415VWFAInterPro annotationAdd BLAST174
Domaini445 – 620VWFAInterPro annotationAdd BLAST176
Domaini639 – 816VWFAInterPro annotationAdd BLAST178
Domaini837 – 1009VWFAInterPro annotationAdd BLAST173
Domaini1029 – 1205VWFAInterPro annotationAdd BLAST177
Domaini1233 – 1404VWFAInterPro annotationAdd BLAST172
Domaini1436 – 1609VWFAInterPro annotationAdd BLAST174
Domaini1639 – 1812VWFAInterPro annotationAdd BLAST174
Domaini1838 – 2024VWFAInterPro annotationAdd BLAST187
Domaini2402 – 2581VWFAInterPro annotationAdd BLAST180
Domaini2619 – 2815VWFAInterPro annotationAdd BLAST197
Domaini2991 – 3082Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini3113 – 3163BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1612 – 1634DisorderedSequence analysisAdd BLAST23
Regioni2041 – 2373DisorderedSequence analysisAdd BLAST333
Regioni2901 – 2992DisorderedSequence analysisAdd BLAST92
Regioni3074 – 3094DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2132 – 2169PolyampholyteSequence analysisAdd BLAST38
Compositional biasi2291 – 2313PolyampholyteSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG41103QR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156462

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M3WHG4

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 1 hit
cd00109 KU, 1 hit
cd01481 vWA_collagen_alpha3-VI-like, 4 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
3.40.50.410, 12 hits
4.10.410.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR041900 vWA_collagen_alpha3-VI-like
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391 Collagen, 2 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 12 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00759 BASICPTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00131 KU, 1 hit
SM00327 VWA, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 1 hit
SSF53300 SSF53300, 12 hits
SSF57362 SSF57362, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 1 hit
PS50234 VWFA, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

M3WHG4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRKHRHLPLV ATFCLFLSGF SLTRAQQQQA DVKNGAAADI IFLVDSSWSI
60 70 80 90 100
GKEHFQLVRE FLYDVIKSLA VGENDFHFAL VQFNGNPHTE FRLNTYRTNQ
110 120 130 140 150
EVLSHISNMS YIGGSNQTGK GLEYVMQNHL TEAAGSRASD GVPQVIVVLT
160 170 180 190 200
GGHSDDGLAL PSAELKSADV NVFAIGVEDS DEGALREIAS EPLNMHVFNL
210 220 230 240 250
ENFTSLHDIV GSLVSCVQSS VAPEGAGGTE TFKDITAQDS ADIIFLIDGS
260 270 280 290 300
NNTGSVHFAV IRDFLVNLLE RLSVGTQQIR VGVVQYSDEP RTMFSLDTYS
310 320 330 340 350
TKVQVLDAVK ALAFTGGELA NIGLALDFVV ENHFTRAGGS RVEEGVPQVL
360 370 380 390 400
VLISAGPSSD EIRDGVIALK QASVFSFGLG TQAASRAELQ HIATSDNLVF
410 420 430 440 450
TVPEFRSFGD LQEQLLLYIV GVAQRRIVLQ PPTIVTEVIE VNKRDIVFLV
460 470 480 490 500
DGSSALGLAN FNAIRDFIAK VIQRLEIGQD LIQVAVAQYA DTVRPEFYFN
510 520 530 540 550
SYPSKREVIA AVRRMKPMEG SALYTGSALD FVRNNLFTSS AGYRAAEGVP
560 570 580 590 600
KLLVLVTGGK SLDEISQPAQ ELKRSSIMSF AIGNKVADQA ELEEIAFDSS
610 620 630 640 650
LVFIPAEFRA APLQGVLPGL LAPLRTLTGT TEVHVNKRDI IFLLDGSFNV
660 670 680 690 700
GKTDFPYVRD FVMNVVNSLD VGSDNIRVGL VQFSDTPVTE FSLNTYQTKS
710 720 730 740 750
DLLAHLRQLQ PKGGSGLNTG AALSYVHANH FTEAGGSRIR EHVPQLLLLV
760 770 780 790 800
TAGQSEDSYG QAANALARAG VLTFCVGASQ ANKAELEQIA FNPSLVYLMD
810 820 830 840 850
DFSSLPALPQ QLIQPLTTYV SGGVEEVPFA QPESKRDILF LFDGSANLVG
860 870 880 890 900
QFPAVRDFLY KVIDELDVKP DGTRIAVAQY SDDVRVESRF DEHQNKPEIL
910 920 930 940 950
NLVKRMKIKT GKALNLGYAL EYAQRYIFVK SAGSRIEDGV VQFLVLLVAG
960 970 980 990 1000
RSSDRLDTPA LSLKQSQVVT FILQAKNADP AELELMVPSP VFILAAESLP
1010 1020 1030 1040 1050
KIGDLQPQIV NLLKSVQDGA PTPVSGEKDV VFLIDGSEGV RSGFPLLKEF
1060 1070 1080 1090 1100
VQRVVESLDV GPDRVRVAVV QYSDRTRPEF YLNSYMDQQS VVSAIRKLAL
1110 1120 1130 1140 1150
LGGPAPNTGA ALDFVLRNIL ISSAGSRIAE GVPQLLIVLT ADRSGDDVRG
1160 1170 1180 1190 1200
PSVVLKRGGA VPIGIGIGNA DITEMQTISF IPDFAVAIPT FRQLGTVQQV
1210 1220 1230 1240 1250
ISDRVIQLSR EELSRLQPVL LPPTIPGVGN KKDVVFLIDG SQNAGPEFQY
1260 1270 1280 1290 1300
IRTLIERLVD YLDVGFDTTR VAVIQFSEDP RVEFLLNAHS SKDEVQNAVR
1310 1320 1330 1340 1350
RLRPKGGRQI NIGGALEYVS RNIFKRPLGS RIEEGVPQFL VLISSGKSDD
1360 1370 1380 1390 1400
EVDDSAAELK QFGVAPFAVA RNADQEQLVK ISLSPEYVFS VSTFRELPSL
1410 1420 1430 1440 1450
EQKLLTPITT LTSEQIQRIL ASTRYPSPDV ESDAADIVFL IDSSDNVRPD
1460 1470 1480 1490 1500
GIAHIRDFVS RIVRRLNIGP NKVRIGVVQF SNEVFPEFYL KTHRSQAPVL
1510 1520 1530 1540 1550
DAIRRLRFKG GSPLNTGKAL EFVARNLFVK SAGSRIEDGV PQHLVLFLGG
1560 1570 1580 1590 1600
KSQDDISRFS QVISSSGIVS LGVGDRNVDR TELQTITNDP RLVFTVREFR
1610 1620 1630 1640 1650
DLPNIEEKIM NSFGPSGITP APPGVDTPSP SRPEKKKADV VFLLDGSINF
1660 1670 1680 1690 1700
RRDSFQEVLR FVSEIVDTLY EGGDSIQVGL VQYNSDPTDE FFLRDFTTKQ
1710 1720 1730 1740 1750
QIIDAINKVV YKGGRHANTK VGLQHLRLNH FVPEAGSRLD QRVPQIAFVI
1760 1770 1780 1790 1800
TGGKSVEDAQ EASLALTQRG VKVFAVGVKN IDSEEIGKIA SNSATAFRVG
1810 1820 1830 1840 1850
NVQELSELSE QVLETLHDAM HETLCPGVTD VSKVCNLDVI LGFDGSRDQN
1860 1870 1880 1890 1900
VFVTQKGLES KVDTILNRIS QMQRISCTGG QMPTVRVSVV ANTPSGPVEA
1910 1920 1930 1940 1950
FDFAEYQPEL FEKFQNMRSQ HPYVLTADTL KVYQNKFRQS SADNVKVVIH
1960 1970 1980 1990 2000
FTDGVDGDLA DLQRASEDLR QEGVQALILV GLERVANLEQ LMQLEFGRGF
2010 2020 2030 2040 2050
MYNRPLRLNL LDLDYELAEQ LDNIAEKACC GVPCKCSGQR GDRGPIGSIG
2060 2070 2080 2090 2100
PKGIPGEDGY RGYPGDEGGP GERGPPGVNG TQGFQGCPGQ RGIKGSRGFP
2110 2120 2130 2140 2150
GEKGELGEIG LDGLNGEDGD KGLPGSPGEK GSPGRRGDKG PKGDKGERGD
2160 2170 2180 2190 2200
VGIRGDPGDS GRDSQQRGPK GETGDIGPMG LPGRDGVSGR PGETGKDGGF
2210 2220 2230 2240 2250
GRRGPAGAKG NKGGPGQPGS VGEQGTRGGQ GPPGPTGPPG LIGEQGISGP
2260 2270 2280 2290 2300
RGSGGTAGAP GERGRVGPLG RKGEPGEPGP KGGVGSRGPR GETGDDGRDG
2310 2320 2330 2340 2350
IGGEGRKGRK GERGFPGYPG PKGAPGEPGT DGGPGPKGIR GRRGNSGPPG
2360 2370 2380 2390 2400
AIGQKGDPGY PGPSGPKGNR GDSMDQCALV QSIKDKCPCC YGPLECPVFP
2410 2420 2430 2440 2450
TELAFALDTS EGVTQDTFSR MRDVLLSIVG DLTIAESNCP RGARVAVVTY
2460 2470 2480 2490 2500
NNEVTTEIRF ADSKKKSVLL DKIKNLQVAL TSKQQSLETA MSFVARNTFK
2510 2520 2530 2540 2550
RVRNGFLMRK VAVFFSNKPT RASPQLREAV LKLSDAGITP LFLTSQEDRQ
2560 2570 2580 2590 2600
LINALQINNT AVGHALVLPP RRDLTNFLKT VLTCHVCLDI CNIDPSCGFG
2610 2620 2630 2640 2650
SWRPSFRDRR AAGSDADIDL AFVLDSSEST SLFQFNEMRK YIGYLVRQLD
2660 2670 2680 2690 2700
LSPDPKAAQH FARVAVVQHA PYESAGNASV PPVKVEVSLT DYGSKEKLVD
2710 2720 2730 2740 2750
FLSSRMTQLQ GTRDLGRAIQ YTIENVFESA PNPRDMKVVV LMLTGEVDKQ
2760 2770 2780 2790 2800
QLEEAQGVIL QAKCKGYFFV ILGIGRKVNV KELYNFASEP SDVFFKLLDK
2810 2820 2830 2840 2850
STELNEEPLM RFGRLLPSFV SSENAFYLSP DIRKQCDWFQ GDQLTKNPVK
2860 2870 2880 2890 2900
FGHKQLNIPN NVTSSPASKL VTTAKPVAST EAVTTTTKPV TVVNLPATKP
2910 2920 2930 2940 2950
VAAKPAAPKP AASRPVSGRP VAAKPEATKT ATVRPAVAAK PAAAKPAAAK
2960 2970 2980 2990 3000
PAAVRPPAAA KPAAAKPEAA KPQATKLATS KTDAAKPVVK ASREVQVSDV
3010 3020 3030 3040 3050
TENSARIHWE RPEPPSPYFY DLTVTSAHDQ SLVLRQNLSV TERAIGGLLA
3060 3070 3080 3090 3100
GHTYHVVVLC YLKSQVRAAY QGSFTTKKAQ PPPSPPQARS ASSSTINLMV
3110 3120 3130 3140 3150
STEPLAGGEA DICKLPKEEG TCRKFILKWY YDADTKSCAR FWYGGCGGNE
3160 3170
NRFNSQKECE KVCAPALVNP GVMAAMGT
Length:3,178
Mass (Da):342,999
Last modified:October 10, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6C650A1F82DCAEC5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A337S4V9A0A337S4V9_FELCA
Uncharacterized protein
COL6A3
2,972Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A337RW59A0A337RW59_FELCA
Uncharacterized protein
COL6A3
2,571Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A337SL76A0A337SL76_FELCA
Uncharacterized protein
COL6A3
2,561Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A337S971A0A337S971_FELCA
Uncharacterized protein
COL6A3
1,030Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AANG04002752 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSFCAT00000012724; ENSFCAP00000011794; ENSFCAG00000012720

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04002752 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000011794

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000012724; ENSFCAP00000011794; ENSFCAG00000012720

Organism-specific databases

VGNCiVGNC:61068 COL6A3

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG41103QR LUCA
GeneTreeiENSGT00940000156462
InParanoidiM3WHG4

Gene expression databases

BgeeiENSFCAG00000012720 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

CDDicd00063 FN3, 1 hit
cd00109 KU, 1 hit
cd01481 vWA_collagen_alpha3-VI-like, 4 hits
Gene3Di2.60.40.10, 1 hit
3.40.50.410, 12 hits
4.10.410.10, 1 hit
InterProiView protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR041900 vWA_collagen_alpha3-VI-like
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF01391 Collagen, 2 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 12 hits
PRINTSiPR00759 BASICPTASE
SMARTiView protein in SMART
SM00131 KU, 1 hit
SM00327 VWA, 12 hits
SUPFAMiSSF49265 SSF49265, 1 hit
SSF53300 SSF53300, 12 hits
SSF57362 SSF57362, 1 hit
PROSITEiView protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 1 hit
PS50234 VWFA, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM3WHG4_FELCA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M3WHG4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: October 10, 2018
Last modified: July 3, 2019
This is version 47 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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