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Protein
Submitted name:

Steroid 5 alpha-reductase 2

Gene

SRD5A2

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Steroid 5 alpha-reductase 2Imported
Gene namesi
Name:SRD5A2Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome A3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei76 – 97HelicalSequence analysisAdd BLAST22
Transmembranei109 – 132HelicalSequence analysisAdd BLAST24
Transmembranei144 – 162HelicalSequence analysisAdd BLAST19
Transmembranei183 – 203HelicalSequence analysisAdd BLAST21
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000010555 Expressed in 3 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000009799

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini149 – 229S5A_REDUCTASEInterPro annotationAdd BLAST81

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1638 Eukaryota
ENOG410XS6P LUCA
GeneTreeiENSGT00510000046634
InParanoidiM3WDH3
KOiK12344
OMAiEYPAEWY
OrthoDBiEOG091G0KU4

Family and domain databases

InterProiView protein in InterPro
IPR016636 3-oxo-5-alpha-steroid_4-DH
IPR001104 3-oxo-5_a-steroid_4-DH_C
IPR039357 SRD5A/TECR
PANTHERiPTHR10556 PTHR10556, 1 hit
PfamiView protein in Pfam
PF02544 Steroid_dh, 1 hit
PIRSFiPIRSF015596 5_alpha-SR2, 1 hit
PROSITEiView protein in PROSITE
PS50244 S5A_REDUCTASE, 1 hit

Sequencei

Sequence statusi: Complete.

M3WDH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVPCQQSPV LAGSAALAAL GALVLYLAEP SGYGKYSERA MPAAARLPAR
60 70 80 90 100
AAWFLQELPS FAVPAGILAR QPRALFGPPA TVLLGLFCGH YFYRTFVYSL
110 120 130 140 150
RTRGRPFPVV FLVKGFVFCM GNGLLQGYYL IYCAEYPADW YTDIRFSLGV
160 170 180 190 200
FLFILGMGIN IHSDCILRQL RKPGEVIYRI PQGGLFTYVS GANFLGEIIE
210 220 230 240 250
WIGYALATWS LPALAFAFFS FCFLGLRAFH HHRFYLKMFE DYPKSRKALI

PFIF
Length:254
Mass (Da):28,551
Last modified:May 1, 2013 - v1
Checksum:iFE141BF9B1E1F572
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG03323542 Genomic DNA No translation available.
AANG03323543 Genomic DNA No translation available.
RefSeqiXP_006930441.1, XM_006930379.3

Genome annotation databases

EnsembliENSFCAT00000010558; ENSFCAP00000009799; ENSFCAG00000010555
GeneIDi101086898
KEGGifca:101086898

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG03323542 Genomic DNA No translation available.
AANG03323543 Genomic DNA No translation available.
RefSeqiXP_006930441.1, XM_006930379.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000009799

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000010558; ENSFCAP00000009799; ENSFCAG00000010555
GeneIDi101086898
KEGGifca:101086898

Organism-specific databases

CTDi6716

Phylogenomic databases

eggNOGiKOG1638 Eukaryota
ENOG410XS6P LUCA
GeneTreeiENSGT00510000046634
InParanoidiM3WDH3
KOiK12344
OMAiEYPAEWY
OrthoDBiEOG091G0KU4

Gene expression databases

BgeeiENSFCAG00000010555 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR016636 3-oxo-5-alpha-steroid_4-DH
IPR001104 3-oxo-5_a-steroid_4-DH_C
IPR039357 SRD5A/TECR
PANTHERiPTHR10556 PTHR10556, 1 hit
PfamiView protein in Pfam
PF02544 Steroid_dh, 1 hit
PIRSFiPIRSF015596 5_alpha-SR2, 1 hit
PROSITEiView protein in PROSITE
PS50244 S5A_REDUCTASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3WDH3_FELCA
AccessioniPrimary (citable) accession number: M3WDH3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: September 12, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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