UniProtKB - M3W4X8 (M3W4X8_FELCA)
Protein
Submitted name:
Forkhead box F2
Gene
FOXF2
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 104 – 198 | Fork-headPROSITE-ProRule annotationAdd BLAST | 95 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: Ensembl
- transcription factor binding Source: Ensembl
GO - Biological processi
- embryonic camera-type eye morphogenesis Source: Ensembl
- embryonic digestive tract development Source: Ensembl
- establishment of planar polarity of embryonic epithelium Source: Ensembl
- extracellular matrix organization Source: Ensembl
- genitalia development Source: Ensembl
- negative regulation of transcription, DNA-templated Source: Ensembl
- regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
- regulation of protein polyubiquitination Source: Ensembl
- roof of mouth development Source: Ensembl
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Forkhead box F2Imported |
Gene namesi | Name:FOXF2Imported |
Organismi | Felis catus (Cat) (Felis silvestris catus)Imported |
Taxonomic identifieri | 9685 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Feliformia › Felidae › Felinae › Felis |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:62333, FOXF2 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- transcription regulator complex Source: Ensembl
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | ENSFCAG00000005901, Expressed in embryonic head and 9 other tissues |
Interactioni
GO - Molecular functioni
- transcription factor binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 9685.ENSFCAP00000005480 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 104 – 198 | Fork-headInterPro annotationAdd BLAST | 95 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 102 | DisorderedSequence analysisAdd BLAST | 102 | |
Regioni | 260 – 327 | DisorderedSequence analysisAdd BLAST | 68 | |
Regioni | 340 – 373 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 22 | Pro-richSequence analysisAdd BLAST | 22 | |
Compositional biasi | 42 – 74 | PolarSequence analysisAdd BLAST | 33 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | M3W4X8 |
OrthoDBi | 1120805at2759 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
i Sequence
Sequence statusi: Complete.
M3W4X8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTEGGPPPP PPRPPPAPLR RACSPAPGAL QAALMSPPPA AAALETTSSS
60 70 80 90 100
SSSSSASCAS SSSASNSASA SSAACKNAGG GGGGASAGSG GAKKASSGLR
110 120 130 140 150
RPEKPPYSYI ALIVMAIQSS PSKRLTLSEI YQFLQARFPF FRGAYQGWKN
160 170 180 190 200
SVRHNLSLNE CFIKLPKGLG RPGKGHYWTI DPASEFMFEE GSFRRRPRGF
210 220 230 240 250
RRKCQALKPM YHRVVSGLGF GASLLPQGFD FQAPPSAPLG CHGQGGYGGL
260 270 280 290 300
DMMPAGYDAS TGAPSHAHPH HHHHHHVPHM SPNPGSTYMA SCPVPAGPGG
310 320 330 340 350
VGAAGGGGGG DYGPDSSSSP VPSSPAMASA IECHSPYTSP AAHWSSPGAS
360 370 380 390 400
PYLKQPPSLT PSSNPAASAG LHSSMSSYSL EQSYLHQNAR EDLSVGLPRY
410 420 430 440
QHHSTPVCDR KDFVLNFNGI SSFHPSASGP YYHHHHHQSV CQDIKPCVM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04001101 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSFCAT00000005901; ENSFCAP00000005480; ENSFCAG00000005901 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04001101 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9685.ENSFCAP00000005480 |
Genome annotation databases
Ensembli | ENSFCAT00000005901; ENSFCAP00000005480; ENSFCAG00000005901 |
Organism-specific databases
VGNCi | VGNC:62333, FOXF2 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | M3W4X8 |
OrthoDBi | 1120805at2759 |
Gene expression databases
Bgeei | ENSFCAG00000005901, Expressed in embryonic head and 9 other tissues |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M3W4X8_FELCA | |
Accessioni | M3W4X8Primary (citable) accession number: M3W4X8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2013 |
Last sequence update: | October 10, 2018 | |
Last modified: | August 12, 2020 | |
This is version 60 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |