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Protein
Submitted name:

Uncharacterized protein

Gene

SLC25A12

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi172 – 183PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotationSAAS annotation
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SLC25A12Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome C1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000004942 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000004574

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 123EF-handInterPro annotationAdd BLAST36
Domaini159 – 194EF-handInterPro annotationAdd BLAST36
Repeati326 – 418SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati426 – 510SolcarPROSITE-ProRule annotationAdd BLAST85
Repeati518 – 606SolcarPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiM3W360
OMAiMQNQRGT
OrthoDBiEOG091G08GT

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS50920 SOLCAR, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

M3W360-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEACQVQTT KRGDPHELRN IFLQYASTEV DGEHYMTPED FVQRYLGLYN
60 70 80 90 100
DPNSNPKVVQ LLAGVADQTK DGLISYQEFL AFESVLCAPD SMFIVAFQLF
110 120 130 140 150
DKSGNGEVTF ENVKEIFGQT IIHHHIPFNW DCEFIRLHFG HNRKKHLNYT
160 170 180 190 200
EFTQFLQELQ LEHARQAFAL KDKSKSGMIS GLDFSDIMVT IRSHMLTPFV
210 220 230 240 250
EENLVSAAGG SISHQVSFSY FNAFNSLLNN MELVRKIYST LAGTRKDVEV
260 270 280 290 300
TKEEFAQSAI RYGQVTPLEI DILYQLADLY NATGRLTLAD IERIAPLAEG
310 320 330 340 350
ALPYNLAELQ RQQSHGLGRP IWLQIAESAY RFTLGSVAGA VGATAVYPID
360 370 380 390 400
LVKTRMQNQR GTGSVVGELM YKNSFDCFKK VLRYEGFFGL YRGLIPQLIG
410 420 430 440 450
VAPEKAIKLT VNDFVRDKFT RRDGSIPLLA EILAGGCAGG SQVIFTNPLE
460 470 480 490 500
IVKIRLQVAG EITTGPRVSA LNVLRDLGLF GLYKGAKACF LRDIPFSAIY
510 520 530 540 550
FPVYAHCKLL LADENGHVGG INLLAAGAMA GVPAASLVTP ADVIKTRLQV
560 570 580 590 600
AARAGQTTYS GVIDCFRKIL REEGPSAFWK GTAARVFRSS PQFGVTLVTY
610 620 630 640 650
ELLQRWFYID FGGLKPSGSE PTPKSRIADL PPANPDHIGG YRLATATFAG
660 670 680
IENKFGLYLP KFKAPSVAVV QSKAVAAAAQ
Length:680
Mass (Da):75,063
Last modified:February 28, 2018 - v2
Checksum:i6F70CADE6457676D
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I2U9X6A0A2I2U9X6_FELCA
Uncharacterized protein
SLC25A12
678Annotation score:
A0A2I2ULF4A0A2I2ULF4_FELCA
Uncharacterized protein
SLC25A12
645Annotation score:
A0A2I2V4I5A0A2I2V4I5_FELCA
Uncharacterized protein
SLC25A12
677Annotation score:
A0A337SL15A0A337SL15_FELCA
Uncharacterized protein
SLC25A12
587Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001482 Genomic DNA No translation available.
RefSeqiXP_019693821.1, XM_019838262.1

Genome annotation databases

EnsembliENSFCAT00000004946; ENSFCAP00000004574; ENSFCAG00000004942
GeneIDi101089635

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001482 Genomic DNA No translation available.
RefSeqiXP_019693821.1, XM_019838262.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000004574

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000004946; ENSFCAP00000004574; ENSFCAG00000004942
GeneIDi101089635

Organism-specific databases

CTDi8604

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiM3W360
OMAiMQNQRGT
OrthoDBiEOG091G08GT

Gene expression databases

BgeeiENSFCAG00000004942 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS50920 SOLCAR, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiM3W360_FELCA
AccessioniPrimary (citable) accession number: M3W360
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: February 28, 2018
Last modified: October 10, 2018
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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