UniProtKB - M3VYV9 (M3VYV9_FELCA)
Protein
Histone acetyltransferase
Gene
KAT7
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 508 | Proton donor/acceptorUniRule annotation | 1 |
GO - Molecular functioni
- histone acetyltransferase activity Source: GO_Central
- histone binding Source: GO_Central
- transcription coregulator activity Source: GO_Central
- zinc ion binding Source: InterPro
GO - Biological processi
- negative regulation of transcription, DNA-templated Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | AcyltransferaseARBA annotation, Transferase |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:KAT7Imported |
Organismi | Felis catus (Cat) (Felis silvestris catus)Imported |
Taxonomic identifieri | 9685 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Feliformia › Felidae › Felinae › Felis |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:63026, KAT7 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nuclear chromatin Source: GO_Central
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSFCAG00000002640, Expressed in testis and 10 other tissues |
Interactioni
GO - Molecular functioni
- histone binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 9685.ENSFCAP00000002433 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 332 – 607 | MYST-type HATInterPro annotationAdd BLAST | 276 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 173 | DisorderedSequence analysisAdd BLAST | 173 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 307 – 327 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 19 – 38 | PolyampholyteSequence analysisAdd BLAST | 20 | |
Compositional biasi | 39 – 106 | PolarSequence analysisAdd BLAST | 68 | |
Compositional biasi | 107 – 123 | PolyampholyteSequence analysisAdd BLAST | 17 | |
Compositional biasi | 124 – 151 | PolarSequence analysisAdd BLAST | 28 | |
Compositional biasi | 153 – 173 | PolyampholyteSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the MYST (SAS/MOZ) family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerARBA annotationPhylogenomic databases
eggNOGi | KOG2747, Eukaryota |
GeneTreei | ENSGT00940000157744 |
HOGENOMi | CLU_011815_6_1_1 |
InParanoidi | M3VYV9 |
OMAi | XVRAQSR |
OrthoDBi | 629545at2759 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR002717, HAT_MYST-type IPR036388, WH-like_DNA-bd_sf IPR040706, Zf-MYST IPR002515, Znf_C2H2C IPR036060, Znf_C2H2C_sf |
Pfami | View protein in Pfam PF01853, MOZ_SAS, 1 hit PF01530, zf-C2HC, 1 hit PF17772, zf-MYST, 1 hit |
SUPFAMi | SSF103637, SSF103637, 1 hit SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51726, MYST_HAT, 1 hit PS51802, ZF_CCHHC, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
M3VYV9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRRKRNAGS SSDGTEDSDF STDLEHTDSS ESDGTSRRSA RVTRSSARLS
60 70 80 90 100
QSSQDSSPVR NLQSFGTEEP AYSTRRVTRS QQQPTPVTPK KYPLRQTRSS
110 120 130 140 150
GSETEQVVDF SDRETKNTAD HDESPPRTPT GNAPSSESDI DISSPNVSHD
160 170 180 190 200
ESMAKDMSLK DSGSDLSHRP KRRRFHESYN FNMKCPTPGC NSLGHLTGKH
210 220 230 240 250
ERHFSISGCP LYHNLSADEC KVRAQSRDKQ IEERMLSHRQ DDNNRHATRH
260 270 280 290 300
QAPTERQLRY KEKVAELRKK RNSGLSKEQK EKYMEHRQTY GNTREPLLEN
310 320 330 340 350
LTSEYDLDLF RRAQARASED LEKLRLQGQI TEGSNMIKTI AFGRYELDTW
360 370 380 390 400
YHSPYPEEYA RLGRLYMCEF CLKYMKSQTI LRRHMAKCVW KHPPGDEIYR
410 420 430 440 450
KGSVSVFEVD GKKNKIYCQN LCLLAKLFLD HKTLYYDVEP FLFYVMTEAD
460 470 480 490 500
NTGCHLIGYF SKEKNSFLNY NVSCILTMPQ YMRQGYGKML IDFSYLLSKV
510 520 530 540 550
EEKVGSPERP LSDLGLISYR SYWKEVLLRY LHNFQGKEIS IKEISQETAV
560 570 580 590 600
NPVDIVSTLQ ALQMLKYWKG KHLVLKRQDL IDEWIAKEAK RSNSNKTMDP
610
SCLKWTPPKG T
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A337SG01 | A0A337SG01_FELCA | Histone acetyltransferase | KAT7 | 614 | Annotation score: | ||
A0A2I2UJF6 | A0A2I2UJF6_FELCA | Histone acetyltransferase | KAT7 | 584 | Annotation score: | ||
A0A337SHR6 | A0A337SHR6_FELCA | Histone acetyltransferase | KAT7 | 472 | Annotation score: | ||
A0A5F5XQJ2 | A0A5F5XQJ2_FELCA | Histone acetyltransferase | KAT7 | 501 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04003358 Genomic DNA No translation available. |
RefSeqi | XP_003996754.1, XM_003996705.4 |
Genome annotation databases
Ensembli | ENSFCAT00000002640; ENSFCAP00000002433; ENSFCAG00000002640 |
GeneIDi | 101093559 |
KEGGi | fca:101093559 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04003358 Genomic DNA No translation available. |
RefSeqi | XP_003996754.1, XM_003996705.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9685.ENSFCAP00000002433 |
Genome annotation databases
Ensembli | ENSFCAT00000002640; ENSFCAP00000002433; ENSFCAG00000002640 |
GeneIDi | 101093559 |
KEGGi | fca:101093559 |
Organism-specific databases
CTDi | 11143 |
VGNCi | VGNC:63026, KAT7 |
Phylogenomic databases
eggNOGi | KOG2747, Eukaryota |
GeneTreei | ENSGT00940000157744 |
HOGENOMi | CLU_011815_6_1_1 |
InParanoidi | M3VYV9 |
OMAi | XVRAQSR |
OrthoDBi | 629545at2759 |
Gene expression databases
Bgeei | ENSFCAG00000002640, Expressed in testis and 10 other tissues |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR002717, HAT_MYST-type IPR036388, WH-like_DNA-bd_sf IPR040706, Zf-MYST IPR002515, Znf_C2H2C IPR036060, Znf_C2H2C_sf |
Pfami | View protein in Pfam PF01853, MOZ_SAS, 1 hit PF01530, zf-C2HC, 1 hit PF17772, zf-MYST, 1 hit |
SUPFAMi | SSF103637, SSF103637, 1 hit SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51726, MYST_HAT, 1 hit PS51802, ZF_CCHHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M3VYV9_FELCA | |
Accessioni | M3VYV9Primary (citable) accession number: M3VYV9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2013 |
Last sequence update: | May 1, 2013 | |
Last modified: | December 2, 2020 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |