UniProtKB - M3VVL1 (M3VVL1_FELCA)
Protein
Submitted name:
Nuclear factor of activated T cells 1
Gene
NFATC1
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- DNA-binding transcription factor activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear factor of activated T cells 1Imported |
Gene namesi | Name:NFATC1Imported |
Organismi | Felis catus (Cat) (Felis silvestris catus)Imported |
Taxonomic identifieri | 9685 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Feliformia › Felidae › Felinae › Felis |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:68469, NFATC1 |
Expressioni
Gene expression databases
Bgeei | ENSFCAG00000000884, Expressed in tip of external ear and 11 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 554 – 736 | RHDInterPro annotationAdd BLAST | 183 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 104 | DisorderedSequence analysisAdd BLAST | 104 | |
Regioni | 193 – 218 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 346 – 444 | DisorderedSequence analysisAdd BLAST | 99 | |
Regioni | 806 – 964 | DisorderedSequence analysisAdd BLAST | 159 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 21 – 43 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 74 – 94 | Pro-richSequence analysisAdd BLAST | 21 | |
Compositional biasi | 380 – 410 | PolarSequence analysisAdd BLAST | 31 | |
Compositional biasi | 421 – 444 | PolarSequence analysisAdd BLAST | 24 |
Phylogenomic databases
eggNOGi | ENOG502QTX8, Eukaryota |
GeneTreei | ENSGT00940000157616 |
HOGENOMi | CLU_010185_1_0_1 |
InParanoidi | M3VVL1 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR008366, NFAT IPR015647, NFAT1 IPR008967, p53-like_TF_DNA-bd IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit PTHR12533:SF5, PTHR12533:SF5, 1 hit |
Pfami | View protein in Pfam PF00554, RHD_DNA_bind, 1 hit |
PRINTSi | PR01789, NUCFACTORATC |
SUPFAMi | SSF49417, SSF49417, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
M3VVL1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRQGGGAGA AGPAGRRGRC FPALKRQEAE RGPASERHSE DSELAGTVTA
60 70 80 90 100
PGRAAGRGHR GAGAHRRAPA TPPPRHAARA PGPRLGPPRA HTPPNDICPG
110 120 130 140 150
RAALSRGRGP CLPGRPGRGG GAERLPLLLP LLLLPAAAAA AAAAWMPSTS
160 170 180 190 200
FPVPSKFPLG PPAAVCGSGE TLGPAPPSGG TMKSAEEEHY SYAPPSIGTA
210 220 230 240 250
LPPGPAHPSL PALCHDLQSA APGMPGAAAG QPPGYGGAVD GGPSGYLLSS
260 270 280 290 300
SHIRPNGAPA LESPRIEITS YMGLHHGNNQ FFHDVEVGDV IPSSKRPPST
310 320 330 340 350
ATLNLPNLEA YRDPSCLSPA SSLSSRSCNS EASSYESNFS YPYASPQTSP
360 370 380 390 400
WQSPCVSPKT TDPEEGFPRG LGACGLLGSP RHSPSTSPRT SVTEESWLGA
410 420 430 440 450
RTSRPSSPCN KRKYGLNGRQ LSCSPHHSPT PSPRSSPRVS VTDDTWLGNS
460 470 480 490 500
TQYTSSAIVA AINALSTDST LELGDGVPVK ARKTALDRCP SVALKVEPAG
510 520 530 540 550
EDLGATPPTS EFLPEEVPPF QHIRKGAFCD QYLSVPQHPY QWARPRSPTS
560 570 580 590 600
YASPSLPALD WQVPSRSGPY ELRIEVQPKP HHRAHYETEG SRGAVKASAG
610 620 630 640 650
GHPSVQLHGY LENEPLTLQL FIGTADDRLL RPHAFYQVHR ITGKTVSTTS
660 670 680 690 700
HEAILSNTKV LEIPLLPENN MRAIVDCAGI LKLRNSDIEL RKGETDIGRK
710 720 730 740 750
NTRVRLVFRV HIPQPNGRTL SLQVASNPIE CSQRSAQELP LVEKQSAASC
760 770 780 790 800
PVLGGKKMVL SGHNFLQDSK VIFVEKAPEF VGGRDTAFPQ SENNEPRPSQ
810 820 830 840 850
FLRLQREEEE EPVSALDLPS CERSNHKNRA RRRPRACPDL WARGPGPEPA
860 870 880 890 900
PAAALQPAAR GATRPGLLPG GRLPALSAEK HRGVAATRHR PGAPRPIFRC
910 920 930 940 950
LRQGHGQPGP RPPWTSAAGR RGARRSGDAE ACGRAPRAPP AAAPRPAATT
960
VNEIIRNDLS STNI
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2I2UJJ5 | A0A2I2UJJ5_FELCA | Nuclear factor of activated T cells... | NFATC1 | 890 | Annotation score: | ||
A0A5F5XKD9 | A0A5F5XKD9_FELCA | Nuclear factor of activated T cells... | NFATC1 | 1,085 | Annotation score: | ||
A0A5F5XIM1 | A0A5F5XIM1_FELCA | Nuclear factor of activated T cells... | NFATC1 | 927 | Annotation score: | ||
A0A5F5XM89 | A0A5F5XM89_FELCA | Nuclear factor of activated T cells... | NFATC1 | 855 | Annotation score: | ||
A0A5F5XXA4 | A0A5F5XXA4_FELCA | Nuclear factor of activated T cells... | NFATC1 | 851 | Annotation score: | ||
A0A5F5XV56 | A0A5F5XV56_FELCA | Nuclear factor of activated T cells... | NFATC1 | 683 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04000315 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSFCAT00000000884; ENSFCAP00000000822; ENSFCAG00000000884 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AANG04000315 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9685.ENSFCAP00000000822 |
Genome annotation databases
Ensembli | ENSFCAT00000000884; ENSFCAP00000000822; ENSFCAG00000000884 |
Organism-specific databases
VGNCi | VGNC:68469, NFATC1 |
Phylogenomic databases
eggNOGi | ENOG502QTX8, Eukaryota |
GeneTreei | ENSGT00940000157616 |
HOGENOMi | CLU_010185_1_0_1 |
InParanoidi | M3VVL1 |
Gene expression databases
Bgeei | ENSFCAG00000000884, Expressed in tip of external ear and 11 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR008366, NFAT IPR015647, NFAT1 IPR008967, p53-like_TF_DNA-bd IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit PTHR12533:SF5, PTHR12533:SF5, 1 hit |
Pfami | View protein in Pfam PF00554, RHD_DNA_bind, 1 hit |
PRINTSi | PR01789, NUCFACTORATC |
SUPFAMi | SSF49417, SSF49417, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M3VVL1_FELCA | |
Accessioni | M3VVL1Primary (citable) accession number: M3VVL1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2013 |
Last sequence update: | December 11, 2019 | |
Last modified: | August 12, 2020 | |
This is version 51 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |