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Protein
Submitted name:

Dopamine receptor D1

Gene

DRD1

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine receptor D1Imported
Gene namesi
Name:DRD1Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome A1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei85 – 110HelicalSequence analysisAdd BLAST26
Transmembranei122 – 139HelicalSequence analysisAdd BLAST18
Transmembranei159 – 180HelicalSequence analysisAdd BLAST22
Transmembranei201 – 222HelicalSequence analysisAdd BLAST22
Transmembranei255 – 278HelicalSequence analysisAdd BLAST24
Transmembranei331 – 351HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000000764 Expressed in 2 organ(s), highest expression level in prefrontal cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000000710

Structurei

3D structure databases

ProteinModelPortaliM3VVD1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 392G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST292

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00890000139331
InParanoidiM3VVD1
OrthoDBiEOG091G06VI

Family and domain databases

InterProiView protein in InterPro
IPR001413 Dopamine_D1_rcpt
IPR000929 Dopamine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR43893:SF10 PTHR43893:SF10, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00565 DOPAMINED1AR
PR00242 DOPAMINER
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

M3VVD1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKSQCFPLG TEGSAGECNS DLEQGSQKTV LESREDLPRG RLGWPRELEG
60 70 80 90 100
VRAPRVHPLS KMRTLNTSTM DGAGLVVERD FSFRILTACF LSLLILSTLL
110 120 130 140 150
GNTLVCAAVI RFRHLRSKVT NFFVISLAVS DLLVAVLVMP WKAVAEIAGF
160 170 180 190 200
WPFGSFCNIW VAFDIMCSTA SILNLCVISV DRYWAISSPF RYERKMTPKA
210 220 230 240 250
AFILIGVAWT LSVLISFIPV QLSWHKAKPT SPSDGNATSL GETTDNCDSS
260 270 280 290 300
LSRTYAISSS LISFYIPVAI MIVTYTRIYR IAQKQIRRIS ALERAAVHAK
310 320 330 340 350
NCQTTTGNGN PAECSQPESS FKMSFKRETK VLKTLSVIMG VFVCCWLPFF
360 370 380 390 400
ILNCMVPFCG SGETKPFCID SITFDVFVWF GWANSSLNPI IYAFNADFRK
410 420 430 440 450
AFSTLLGCYR LCPTTNNAIE TVSINNNGAV VFSSHHEPRG SISKDCNLVY
460 470 480 490 500
LIPHAVGSSQ DLKKEEACGT ARPLEKLSPA LSVILDYDTD VSLEKIQPIT

QNGQHPT
Length:507
Mass (Da):56,024
Last modified:February 28, 2018 - v2
Checksum:i3EF24E694362A3F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001174 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSFCAT00000000764; ENSFCAP00000000710; ENSFCAG00000000764
ENSFCAT00000059469; ENSFCAP00000049433; ENSFCAG00000000764

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04001174 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM3VVD1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000000710

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000000764; ENSFCAP00000000710; ENSFCAG00000000764
ENSFCAT00000059469; ENSFCAP00000049433; ENSFCAG00000000764

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00890000139331
InParanoidiM3VVD1
OrthoDBiEOG091G06VI

Gene expression databases

BgeeiENSFCAG00000000764 Expressed in 2 organ(s), highest expression level in prefrontal cortex

Family and domain databases

InterProiView protein in InterPro
IPR001413 Dopamine_D1_rcpt
IPR000929 Dopamine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR43893:SF10 PTHR43893:SF10, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00565 DOPAMINED1AR
PR00242 DOPAMINER
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3VVD1_FELCA
AccessioniPrimary (citable) accession number: M3VVD1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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