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Protein

Alpha-galactosidase

Gene

SEPMUDRAFT_119573

Organism
Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.UniRule annotation

Catalytic activityi

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei496NucleophileUniRule annotation1
Active sitei558Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-galactosidaseUniRule annotation (EC:3.2.1.22UniRule annotation)
Gene namesi
ORF Names:SEPMUDRAFT_119573Imported
OrganismiSphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria musiva)Imported
Taxonomic identifieri692275 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetidaeCapnodialesMycosphaerellaceaeSphaerulina
Proteomesi
  • UP000016931 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500403239920 – 750Alpha-galactosidaseSequence analysisAdd BLAST731

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 290Glyco_hydro_36NInterPro annotationAdd BLAST242
Domaini670 – 747Glyco_hydro_36CInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the glycosyl hydrolase.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

OrthoDBiEOG092C0NDW

Family and domain databases

CDDicd14791 GH36, 1 hit
Gene3Di2.60.40.1180, 1 hit
2.70.98.60, 1 hit
3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR038417 Alpga-gal_N_sf
IPR002252 Glyco_hydro_36
IPR031705 Glyco_hydro_36_C
IPR031704 Glyco_hydro_36_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF16874 Glyco_hydro_36C, 1 hit
PF16875 Glyco_hydro_36N, 1 hit
PF02065 Melibiase, 1 hit
PIRSFiPIRSF005536 Agal, 1 hit
PRINTSiPR00743 GLHYDRLASE36
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

M3CBM8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRGSNGIALL ASLTSVVLGQ SAIQADGTNF TLTGDGVSYL FHVDHESGDL
60 70 80 90 100
VSDHFGGPTT DFVPAAPIST QGWHDGLANV RREFPDVGRS DLRLPAIHIR
110 120 130 140 150
HSDSSTVSAF AYQSHEVMDG KPPLPGLPAT FGNAEDVSTV KVTMYDNYSD
160 170 180 190 200
VTAVLSYSIF PRYNAIARSF QIMNNGSNDI VIERAASFST DMPNLDLDMI
210 220 230 240 250
ELQGDWSHEM NKVIRKVQYG ETGFRSTEGY SSHTHNPFFA LMEPTTTETS
260 270 280 290 300
GEVWGFNLVY TGSFAATVER FSHGYVRVLL GLNEIHSSLT VAPGETFTSP
310 320 330 340 350
EAVAVYSSQG LGGMSRSFHS LYRHHLSRSN YTLQTRPVLL NSWEGLGFNY
360 370 380 390 400
TASSLERLAG EADALGIKLF VNDDGWFGTE YPRNNDTLGL GDWTPNPAKF
410 420 430 440 450
PEGLGPYVAA VNNVSTTGPD PEPLKFGLWL EPEMVNPNST LYHEHPEWVM
460 470 480 490 500
KSGQHAQTLT RNQLVLNLAL PEVQDYIIQF VSEILDSANI EYIKWDNNRA
510 520 530 540 550
IHEMPRPSTS HSYILGLYHI IDILTTKYPR ILWEGCASGG GRFDAGLLHY
560 570 580 590 600
WPQSWTSDNT DGSNRLTIQL GTSLAYPPSA MGCHVSKVPN GLTGRNISIE
610 620 630 640 650
YRSHVALMCG SFGFELNPSE LSPEEISAIP EIMALAARIN PIVINGDFYR
660 670 680 690 700
LRTPSPSSSY SPSSSTSDNW PAVQFLSANK TTAIVFAFQQ SAMIKPAPPP
710 720 730 740 750
LKLQGLEAEA RYWNSADNGT YWGKSYMSAG LNLDWETRDY QSVVLWLYKV
Length:750
Mass (Da):82,698
Last modified:May 1, 2013 - v1
Checksum:iF31A4B630753871C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB456268 Genomic DNA Translation: EMF09832.1
RefSeqiXP_016757953.1, XM_016901529.1

Genome annotation databases

EnsemblFungiiEMF09832; EMF09832; SEPMUDRAFT_119573
GeneIDi27898666

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB456268 Genomic DNA Translation: EMF09832.1
RefSeqiXP_016757953.1, XM_016901529.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEMF09832; EMF09832; SEPMUDRAFT_119573
GeneIDi27898666

Phylogenomic databases

OrthoDBiEOG092C0NDW

Family and domain databases

CDDicd14791 GH36, 1 hit
Gene3Di2.60.40.1180, 1 hit
2.70.98.60, 1 hit
3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR038417 Alpga-gal_N_sf
IPR002252 Glyco_hydro_36
IPR031705 Glyco_hydro_36_C
IPR031704 Glyco_hydro_36_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF16874 Glyco_hydro_36C, 1 hit
PF16875 Glyco_hydro_36N, 1 hit
PF02065 Melibiase, 1 hit
PIRSFiPIRSF005536 Agal, 1 hit
PRINTSiPR00743 GLHYDRLASE36
SUPFAMiSSF51445 SSF51445, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM3CBM8_SPHMS
AccessioniPrimary (citable) accession number: M3CBM8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: March 28, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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