Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Potassium two pore domain channel subfamily K member 5

Gene

Kcnk5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-RNO-5576886 Phase 4 - resting membrane potential

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium two pore domain channel subfamily K member 5Imported
Gene namesi
Name:Kcnk5Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1564985 Kcnk5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Transmembranei85 – 104HelicalSequence analysisAdd BLAST20
Transmembranei116 – 137HelicalSequence analysisAdd BLAST22
Transmembranei158 – 182HelicalSequence analysisAdd BLAST25
Transmembranei194 – 213HelicalSequence analysisAdd BLAST20
Transmembranei225 – 244HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiM0R8B9

Expressioni

Gene expression databases

BgeeiENSRNOG00000047005

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000065715

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 137Ion_trans_2InterPro annotationAdd BLAST60
Domaini172 – 248Ion_trans_2InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00760000118858
InParanoidiM0R8B9
OMAiYFVELWI
OrthoDBiEOG091G058Z

Family and domain databases

InterProiView protein in InterPro
IPR003280 2pore_dom_K_chnl
IPR003092 2pore_dom_K_chnl_TASK
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF07885 Ion_trans_2, 2 hits
PRINTSiPR01333 2POREKCHANEL
PR01095 TASKCHANNEL

Sequencei

Sequence statusi: Complete.

M0R8B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDRGPLLTS AIIFYLAIGA AIFEVLEEPH WKEAKKNYYT QKLHLLKEFP
60 70 80 90 100
CLSQEGLDKI LQVVSDAADQ GVAITGNQTF NNWNWPNAMI FAATVITTIG
110 120 130 140 150
YGNVAPKTPA GRLFSVFYGL FGVPLCLTCI SALGKFFGGR AKRLGQFLTR
160 170 180 190 200
RGVSLRKAQI TCTAIFIVWG VLVHLVIPPF VFMVTEEWNY IEGLYYSFIT
210 220 230 240 250
ISTIGFGDFV AGVNPSANYH ALYRYFVELW IYLGLAWLSL FVNWKVSMFV
260 270 280 290 300
EVHKAIKKRR RRRKESFESS PHSRKALQMA GSTASKDVNI FSFLSKKEET
310 320 330 340 350
YNDLIKQIGK KAMKTSGGGE RVPGPGHGLG AQGGDGLPSI PASLAPLVVY
360 370 380 390 400
SKNRVPSLEE VSQTLRNKGH VSRPLGEDAA AQTPKEGYPT SEVFINQLDR
410 420 430 440 450
ISEEGEPWEA LDYHPLIFQN ANITFENEET GLSDEETSKS SVEDNLTSKE
460 470 480 490 500
QPQPGPMTEV PSSSTGEFPS SDESTFTSTE SELSVPYEKL MNEYNKADSP

RGT
Length:503
Mass (Da):55,779
Last modified:July 22, 2015 - v2
Checksum:i5AEAC1AB8CC9D0CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07016899 Genomic DNA No translation available.
AABR07016900 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000075153; ENSRNOP00000065715; ENSRNOG00000047005

Similar proteinsi

Entry informationi

Entry nameiM0R8B9_RAT
AccessioniPrimary (citable) accession number: M0R8B9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 35 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health