Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 46 (26 Feb 2020)
Sequence version 1 (03 Apr 2013)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

MMS19 homolog, cytosolic iron-sulfur assembly component

Gene

Mms19

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MMS19 homolog, cytosolic iron-sulfur assembly componentImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mms19Imported
Synonyms:Mms19lImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Rat genome database

More...
RGDi
727890 Mms19

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
M0R6T4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
M0R6T4

PRoteomics IDEntifications database

More...
PRIDEi
M0R6T4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
M0R6T4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
M0R6T4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000046769 Expressed in heart and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000065140

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 312MMS19_NInterPro annotationAdd BLAST262
Domaini545 – 963MMS19_CInterPro annotationAdd BLAST419

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1967 Eukaryota
ENOG410XNMZ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015583

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005943_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
M0R6T4

KEGG Orthology (KO)

More...
KOi
K15075

Identification of Orthologs from Complete Genome Data

More...
OMAi
FEIFACY

Database of Orthologous Groups

More...
OrthoDBi
944339at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR039920 MET18/MMS19
IPR024687 MMS19_C
IPR029240 MMS19_N

The PANTHER Classification System

More...
PANTHERi
PTHR12891 PTHR12891, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12460 MMS19_C, 1 hit
PF14500 MMS19_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

M0R6T4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAATALEEA AAPMGALCGL VQDFVMGQQE GPADQVAADV KSGGYTVLQV
60 70 80 90 100
VEALGSSLEN PEPRTRARGI QLLSQVLLQC HSLLLEKEAV HLTLFYENRL
110 120 130 140 150
KDHHLVVPSV LQGLRALSLS VALPRGLAVS VLKAIFQEVH VQSLLQVDRH
160 170 180 190 200
TVFSIITNFM RSREEELKSL GADFTFGFIQ VMDGEKDPRN LLLAFRIVHD
210 220 230 240 250
LISKDYNLGP FVEELFEVTS CYFPIDFTPP PNDPYGIQRE DLILSLRAVL
260 270 280 290 300
ASTPRFAEFL LPLLIEKVDS EILSAKLDSL QTLNACCAVY GQKELKDFLP
310 320 330 340 350
SLWASIRREV FQTASERVEA EGLAALHSLT ACLSCSVLRA DAEDLLHPFL
360 370 380 390 400
SSILQDCRHH LCEPDMKLVW PSAKLLQAAA GASARACEHI TSNVLPLLLE
410 420 430 440 450
QFHKHSQSNQ RRTILEMILG FLKLQQKWSY EDRDERPLSN FKDQLCSLVF
460 470 480 490 500
MALTDPSTQL QLVGIRMLTV LGAQPDLLSA EDLELAVGHL YRLSLLEEDA
510 520 530 540 550
QSCRVAALEA SGSLATLYPG AFSSHLLPRL AEGLHQGESD VARADGPTKC
560 570 580 590 600
SRHFRCLQAL SAVSTHPDIV KETLPLLLQH LCQAHKGNMI TESSEVVAVC
610 620 630 640 650
QSLQQVAEKC QQDPESYWYF HKTAVPCLFA LAVQASVPEK ASSVLSKALL
660 670 680 690 700
EDEVLAALAS VIGTATTHLS PELAAQSVTC IVPLFLDGNT SFLPENSFPG
710 720 730 740 750
HFQPFQGGSS GQRRLVALLM AFVCSLPRNV EIPELTRLMQ ELLKQSCGHS
760 770 780 790 800
CPFSSTAASK CFAGLLNKQP PGQQLDEFLQ LSVDTVEAGL ASESSRNQAF
810 820 830 840 850
TLLLWVTKAL VLRYHPLSAS LTARLMGLLS DPELGCAAAD GFSLLMSDCT
860 870 880 890 900
DVLTRAGHAD VRIMFRQRFF TDNVPALVQG FHAAPQDVKP NYLKGLSHVL
910 920 930 940 950
NRLPKPVLLP ELPTLLSLLL EALSCPDSVV QLSTLSCLQP LLLEAPQIMS
960 970 980 990 1000
LHVDTLVTKF LNLSSSHSMA VRIAALQCMH ALTRLPTSVL LPFKSQVIRA
1010 1020 1030
LAKPLDDKKR LVRKEAVSAR GEWFLLGSPG S
Length:1,031
Mass (Da):112,932
Last modified:April 3, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1909A0A2CEF3187
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07006869 Genomic DNA No translation available.
AABR07006870 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001258525.1, NM_001271596.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000075531; ENSRNOP00000065140; ENSRNOG00000046769

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
171124

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:171124

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07006869 Genomic DNA No translation available.
AABR07006870 Genomic DNA No translation available.
RefSeqiNP_001258525.1, NM_001271596.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000065140

PTM databases

iPTMnetiM0R6T4
PhosphoSitePlusiM0R6T4

Proteomic databases

jPOSTiM0R6T4
PaxDbiM0R6T4
PRIDEiM0R6T4

Genome annotation databases

EnsembliENSRNOT00000075531; ENSRNOP00000065140; ENSRNOG00000046769
GeneIDi171124
KEGGirno:171124

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64210
RGDi727890 Mms19

Phylogenomic databases

eggNOGiKOG1967 Eukaryota
ENOG410XNMZ LUCA
GeneTreeiENSGT00390000015583
HOGENOMiCLU_005943_2_0_1
InParanoidiM0R6T4
KOiK15075
OMAiFEIFACY
OrthoDBi944339at2759

Gene expression databases

BgeeiENSRNOG00000046769 Expressed in heart and 9 other tissues

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR039920 MET18/MMS19
IPR024687 MMS19_C
IPR029240 MMS19_N
PANTHERiPTHR12891 PTHR12891, 1 hit
PfamiView protein in Pfam
PF12460 MMS19_C, 1 hit
PF14500 MMS19_N, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiM0R6T4_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: M0R6T4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: February 26, 2020
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again