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Protein
Submitted name:

Nuclear receptor subfamily 2, group E, member 1

Gene

Nr2e1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 2, group E, member 1Imported
Submitted name:
RCG58537Imported
Gene namesi
Name:Nr2e1Imported
ORF Names:rCG_58537Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1595162 Nr2e1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiM0R4V9

Expressioni

Gene expression databases

BgeeiENSRNOG00000050550 Expressed in 2 organ(s), highest expression level in brain

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064408

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 90Nuclear receptorInterPro annotationAdd BLAST78
Domaini155 – 383NR LBDInterPro annotationAdd BLAST229

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili258 – 278Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118948
OMAiFPGVPMP
OrthoDBiEOG091G0AV3

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

M0R4V9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKPAGSTSR ILDIPCKVCG DRSSGKHYGV YACDGCSGFF KRSIRRNRTY
60 70 80 90 100
VCKSGNQGGC PVDKTHRNQC RACRLKKCLE VNMNKDAVQH ERGPRTSTIR
110 120 130 140 150
KQVALYFRGH KEDNGAAAHF PSAALPAPAF FTAVTQLEPH GLELTAVSAT
160 170 180 190 200
PERQTLVSLA QPTPKYPHEV NGTPMYLYEV ATESVCESAA RLLFMSIKWA
210 220 230 240 250
KSVPAFSTLS LQDQLMLLED AWRELFVLGI AQWAIPVDAN TLLAVSGMNS
260 270 280 290 300
DNTDSQKLNK IISEIQALQE VVARFRQLRL DATEFACLKC IVTFKAVPTH
310 320 330 340 350
SGSELRSFRN AAAIAALQDE AQLTLNSYIH TRYPTQPCRF GKLLLLLPAL
360 370 380
RSISPSTIEE VFFKKTIGNV PITRLLSDMY KSSDI
Length:385
Mass (Da):42,605
Last modified:April 3, 2013 - v1
Checksum:iF4639E5803304DDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07045433 Genomic DNA No translation available.
AABR07045434 Genomic DNA No translation available.
CH474025 Genomic DNA Translation: EDL99704.1
UniGeneiRn.218964

Genome annotation databases

EnsembliENSRNOT00000075151; ENSRNOP00000064408; ENSRNOG00000050550

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07045433 Genomic DNA No translation available.
AABR07045434 Genomic DNA No translation available.
CH474025 Genomic DNA Translation: EDL99704.1
UniGeneiRn.218964

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064408

Proteomic databases

PRIDEiM0R4V9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000075151; ENSRNOP00000064408; ENSRNOG00000050550

Organism-specific databases

RGDi1595162 Nr2e1

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118948
OMAiFPGVPMP
OrthoDBiEOG091G0AV3

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Gene expression databases

BgeeiENSRNOG00000050550 Expressed in 2 organ(s), highest expression level in brain

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0R4V9_RAT
AccessioniPrimary (citable) accession number: M0R4V9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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