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Protein
Submitted name:

IgG receptor FcRn large subunit p51

Gene

FCGRT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
IgG receptor FcRn large subunit p51Imported
Gene namesi
Name:FCGRTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000104870.12
HGNCiHGNC:3621 FCGRT

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104870

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500400430624 – 141Sequence analysisAdd BLAST118

Proteomic databases

PeptideAtlasiM0R266
PRIDEiM0R266

Expressioni

Gene expression databases

BgeeiENSG00000104870 Expressed in 208 organ(s), highest expression level in mucosa of transverse colon
ExpressionAtlasiM0R266 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 141MHC_I-like_Ag-recogInterPro annotationAdd BLAST115

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IPRY Eukaryota
ENOG4111C4R LUCA
GeneTreeiENSGT00740000114936

Family and domain databases

Gene3Di3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
PfamiView protein in Pfam
PF00129 MHC_I, 1 hit
SUPFAMiSSF54452 SSF54452, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

M0R266-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVPRPQPWA LGLLLFLLPG SLGAESHLSL LYHLTAVSSP APGTPAFWVS
60 70 80 90 100
GWLGPQQYLS YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE
110 120 130 140
AFKALGGKGP YTLQGLLGCE LGPDNTSVPT AKFALNGEEF M
Length:141
Mass (Da):15,498
Last modified:April 3, 2013 - v1
Checksum:iE9C47BBC61772EF2
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P55899FCGRN_HUMAN
IgG receptor FcRn large subunit p51
FCGRT FCRN
365Annotation score:
M0R0A9M0R0A9_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
273Annotation score:
M0R0K7M0R0K7_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
99Annotation score:
M0QYN9M0QYN9_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
225Annotation score:
M0QYN1M0QYN1_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
211Annotation score:
M0QYM4M0QYM4_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
167Annotation score:
M0R0H0M0R0H0_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
153Annotation score:
M0R220M0R220_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
189Annotation score:
M0R2T3M0R2T3_HUMAN
IgG receptor FcRn large subunit p51
FCGRT
38Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010619 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000598491; ENSP00000472350; ENSG00000104870
UCSCiuc061bes.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010619 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM0R266
PRIDEiM0R266

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000598491; ENSP00000472350; ENSG00000104870
UCSCiuc061bes.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000104870.12
HGNCiHGNC:3621 FCGRT
OpenTargetsiENSG00000104870
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IPRY Eukaryota
ENOG4111C4R LUCA
GeneTreeiENSGT00740000114936

Miscellaneous databases

ChiTaRSiFCGRT human

Gene expression databases

BgeeiENSG00000104870 Expressed in 208 organ(s), highest expression level in mucosa of transverse colon
ExpressionAtlasiM0R266 baseline and differential

Family and domain databases

Gene3Di3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
PfamiView protein in Pfam
PF00129 MHC_I, 1 hit
SUPFAMiSSF54452 SSF54452, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0R266_HUMAN
AccessioniPrimary (citable) accession number: M0R266
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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