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Protein
Submitted name:

Spectrin beta chain, non-erythrocytic 4

Gene

SPTBN4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Spectrin beta chain, non-erythrocytic 4Imported
Gene namesi
Name:SPTBN4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000160460.15
HGNCiHGNC:14896 SPTBN4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160460

PTM / Processingi

Proteomic databases

PeptideAtlasiM0R1V6
PRIDEiM0R1V6

Expressioni

Gene expression databases

BgeeiENSG00000160460 Expressed in 178 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiM0R1V6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0R1V6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili18 – 38Sequence analysisAdd BLAST21
Coiled coili147 – 167Sequence analysisAdd BLAST21
Coiled coili517 – 537Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0035 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000118813

Family and domain databases

InterProiView protein in InterPro
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PfamiView protein in Pfam
PF00435 Spectrin, 3 hits
SMARTiView protein in SMART
SM00150 SPEC, 6 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

M0R1V6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PCDPQVICNR VNHVHGCLAE LQEQAARRRA ELEASRSLWA LLQELEEAES
60 70 80 90 100
WARDKERLLE AAGGGGAAGA AGAAGTAGGA HDLSSTARLL AQHKILQGEL
110 120 130 140 150
GGRRALLQQA LRCGEELVAA GGAVGPGADT VHLVGLAERA ASARRRWQRL
160 170 180 190 200
EEAAARRERR LQEARALHQF GADLDGLLDW LRDAYRLAAA GDFGHDEASS
210 220 230 240 250
RRLARQHRAL TGEVEAHRGP VSGLRRQLAT LGGASGAGPL VVALQVRVVE
260 270 280 290 300
AEQLFAEVTE VAALRRQWLR DALAVYRMFG EVHACELWIG EKEQWLLSMR
310 320 330 340 350
VPDSLDDVEV VQHRFESLDQ EMNSLMGRVL DVNHTVQELV EGGHPSSDEV
360 370 380 390 400
RSCQDHLNSR WNRIVELVEQ RKEEMSAVLL VENHVLEVAE VRAQVREKRR
410 420 430 440 450
AVESAPRAGG ALQWRLSGLE AALQALEPRQ AALLEEAALL AERFPAQAAR
460 470 480 490 500
LHQGAEELGA EWGALASAAQ ACGEAVAAAG RLQRFLHDLD AFLDWLVRAQ
510 520 530 540 550
EAAGGSEGPL PNSLEEADAL LARHAALKEE VDQREEDYAR IVAASEALLA
560 570 580 590 600
ADGAELGPGL ALDEWLPHLE LGWHKLLGLW EARREALVQA HIYQLFLRDL
610 620 630 640 650
RQALVVLRNQ EMALSGAELP GTVESVEEAL KQHRDFLTTM ELSQQKMQVA
660 670 680 690 700
VQAAEGLLRQ GNIYGEQAQE AVTRLLEKCL IIHPALLHPP WEPPDLPRSS

S
Length:701
Mass (Da):76,737
Last modified:April 3, 2013 - v1
Checksum:i1B9486C420CD69BD
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9H254SPTN4_HUMAN
Spectrin beta chain, non-erythrocyt...
SPTBN4 KIAA1642, SPTBN3
2,564Annotation score:
C9JY79C9JY79_HUMAN
Spectrin beta chain
SPTBN4 SPNB4
2,564Annotation score:
M0QZQ3M0QZQ3_HUMAN
Spectrin beta chain
SPTBN4
2,002Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020929 Genomic DNA No translation available.
KF511269 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000597389; ENSP00000472136; ENSG00000160460
UCSCiuc060yss.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020929 Genomic DNA No translation available.
KF511269 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0R1V6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM0R1V6
PRIDEiM0R1V6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000597389; ENSP00000472136; ENSG00000160460
UCSCiuc060yss.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000160460.15
HGNCiHGNC:14896 SPTBN4
OpenTargetsiENSG00000160460
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0035 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000118813

Gene expression databases

BgeeiENSG00000160460 Expressed in 178 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiM0R1V6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PfamiView protein in Pfam
PF00435 Spectrin, 3 hits
SMARTiView protein in SMART
SM00150 SPEC, 6 hits
ProtoNetiSearch...

Entry informationi

Entry nameiM0R1V6_HUMAN
AccessioniPrimary (citable) accession number: M0R1V6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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