UniProtKB - M0R1S6 (M0R1S6_HUMAN)
Protein
Peptidylprolyl isomerase
Gene
FKBP8
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:5.2.1.8PROSITE-ProRule annotation
GO - Molecular functioni
- peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Isomerase, RotamasePROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Peptidylprolyl isomerasePROSITE-ProRule annotation (EC:5.2.1.8PROSITE-ProRule annotation) |
Gene namesi | Name:FKBP8Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3724, FKBP8 |
VEuPathDBi | HostDB:ENSG00000105701.15 |
Expressioni
Gene expression databases
Bgeei | ENSG00000105701, Expressed in anterior cingulate cortex and 224 other tissues |
ExpressionAtlasi | M0R1S6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 120 – 167 | PPIase FKBP-typeInterPro annotationAdd BLAST | 48 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 72 | DisorderedSequence analysisAdd BLAST | 72 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 25 – 53 | AcidicSequence analysisAdd BLAST | 29 |
Phylogenomic databases
GeneTreei | ENSGT00940000156705 |
Family and domain databases
InterProi | View protein in InterPro IPR001179, PPIase_FKBP_dom |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
M0R1S6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASCAEPSEP SAPLPAGVPP LEDFEVLDGV EDAEGEEEEE EEEEEEDDLS
60 70 80 90 100
ELPPLEDMGQ PPAEEAEQPG ALAREFLAAM EPEPAPAPAP EEWLDILGNG
110 120 130 140 150
LLRKKTLVPG PPGSSRPVKG QVVTVHLQTS LENGTRVQEE PELVFTLGDC
160
DVIQALDLSV PLMDVGE
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ14318 | FKBP8_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 FKBP38 | 412 | Annotation score: | ||
A0A0A0MTJ1 | A0A0A0MTJ1_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 | 249 | Annotation score: | ||
U3KQ64 | U3KQ64_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 | 182 | Annotation score: | ||
M0R2K9 | M0R2K9_HUMAN | Peptidylprolyl isomerase | FKBP8 | 257 | Annotation score: | ||
M0R2Q6 | M0R2Q6_HUMAN | Peptidylprolyl isomerase | FKBP8 | 204 | Annotation score: | ||
M0R1Q0 | M0R1Q0_HUMAN | Peptidylprolyl isomerase | FKBP8 | 163 | Annotation score: | ||
U3KQI1 | U3KQI1_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 | 103 | Annotation score: | ||
M0R304 | M0R304_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 | 116 | Annotation score: | ||
V9GZ05 | V9GZ05_HUMAN | Peptidyl-prolyl cis-trans isomerase... | FKBP8 | 23 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 167 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005387 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000594844; ENSP00000472087; ENSG00000105701 |
UCSCi | uc060vry.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005387 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | M0R1S6 |
Protocols and materials databases
Antibodypediai | 28073, 401 antibodies |
Genome annotation databases
Ensembli | ENST00000594844; ENSP00000472087; ENSG00000105701 |
UCSCi | uc060vry.1, human |
Organism-specific databases
HGNCi | HGNC:3724, FKBP8 |
OpenTargetsi | ENSG00000105701 |
VEuPathDBi | HostDB:ENSG00000105701.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156705 |
Miscellaneous databases
ChiTaRSi | FKBP8, human |
Gene expression databases
Bgeei | ENSG00000105701, Expressed in anterior cingulate cortex and 224 other tissues |
ExpressionAtlasi | M0R1S6, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001179, PPIase_FKBP_dom |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M0R1S6_HUMAN | |
Accessioni | M0R1S6Primary (citable) accession number: M0R1S6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 3, 2013 |
Last sequence update: | October 5, 2016 | |
Last modified: | April 7, 2021 | |
This is version 65 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |