Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Kallikrein-10

Gene

KLK10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein-10Imported
Gene namesi
Name:KLK10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000129451.11
HGNCiHGNC:6358 KLK10

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000129451

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_500400373934 – 143Sequence analysisAdd BLAST110

Proteomic databases

PeptideAtlasiM0R132
PRIDEiM0R132

Expressioni

Gene expression databases

BgeeiENSG00000129451 Expressed in 119 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiM0R132 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0R132
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 143Peptidase S1InterPro annotationAdd BLAST97

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00930000151066

Family and domain databases

InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

M0R132-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRAPHLHLSA ASGARALAKL LPLLMAQLWA AEAALLPQND TRLDPEAYGS
60 70 80 90 100
PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH
110 120 130 140
LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKL
Length:143
Mass (Da):15,736
Last modified:April 3, 2013 - v1
Checksum:i81B6AB3DD2B8C664
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43240KLK10_HUMAN
Kallikrein-10
KLK10 NES1, PRSSL1
276Annotation score:
M0R2S4M0R2S4_HUMAN
Kallikrein-10
KLK10
43Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei143Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011473 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000599077; ENSP00000471610; ENSG00000129451
UCSCiuc061bvr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011473 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0R132
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM0R132
PRIDEiM0R132

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000599077; ENSP00000471610; ENSG00000129451
UCSCiuc061bvr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000129451.11
HGNCiHGNC:6358 KLK10
OpenTargetsiENSG00000129451
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00930000151066

Miscellaneous databases

ChiTaRSiKLK10 human

Gene expression databases

BgeeiENSG00000129451 Expressed in 119 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiM0R132 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0R132_HUMAN
AccessioniPrimary (citable) accession number: M0R132
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again