Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

DNA repair protein XRCC1

Gene

XRCC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair protein XRCC1Imported
Gene namesi
Name:XRCC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000073050.11
HGNCiHGNC:12828 XRCC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000073050

PTM / Processingi

Proteomic databases

MaxQBiM0R0D2
PeptideAtlasiM0R0D2
PRIDEiM0R0D2

Expressioni

Gene expression databases

BgeeiENSG00000073050 Expressed in 221 organ(s), highest expression level in right ovary
ExpressionAtlasiM0R0D2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0R0D2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 112XRCC1_NInterPro annotationAdd BLAST65

Phylogenomic databases

GeneTreeiENSGT00390000004140

Family and domain databases

Gene3Di2.60.120.260, 2 hits
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR002706 Xrcc1_N
PfamiView protein in Pfam
PF01834 XRCC1_N, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

M0R0D2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPEIRLRHVV SCSSQDSTHC AENLLKADTY RKWRAAKAGE KTISVVLQVL
60 70 80 90 100
LVTSSFMSPS ESRSGSNPNR VRMFGPDKLV RAAAEKRWDR VKIVCSQPYS
110 120 130 140 150
KDSPFGLSFV RFHSPPDKDE AEAPSQKVTV TKLGQFRVKE EDESANSLRP
160 170
GALFFSRINK TSPVTASDPA GP
Length:172
Mass (Da):19,053
Last modified:April 3, 2013 - v1
Checksum:i5E32976E56A2C8E8
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P18887XRCC1_HUMAN
DNA repair protein XRCC1
XRCC1
633Annotation score:
F5H8D7F5H8D7_HUMAN
DNA repair protein XRCC1
XRCC1
602Annotation score:
M0QYS5M0QYS5_HUMAN
DNA repair protein XRCC1
XRCC1
292Annotation score:
M0R1U8M0R1U8_HUMAN
DNA repair protein XRCC1
XRCC1
210Annotation score:
M0QZ96M0QZ96_HUMAN
DNA repair protein XRCC1
XRCC1
165Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei172Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006276 Genomic DNA No translation available.
AC018758 Genomic DNA No translation available.
KC877750 Genomic DNA No translation available.
L34079 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000594107; ENSP00000471159; ENSG00000073050
UCSCiuc060zlz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006276 Genomic DNA No translation available.
AC018758 Genomic DNA No translation available.
KC877750 Genomic DNA No translation available.
L34079 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0R0D2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiM0R0D2
PeptideAtlasiM0R0D2
PRIDEiM0R0D2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000594107; ENSP00000471159; ENSG00000073050
UCSCiuc060zlz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000073050.11
HGNCiHGNC:12828 XRCC1
OpenTargetsiENSG00000073050
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000004140

Miscellaneous databases

ChiTaRSiXRCC1 human

Gene expression databases

BgeeiENSG00000073050 Expressed in 221 organ(s), highest expression level in right ovary
ExpressionAtlasiM0R0D2 baseline and differential

Family and domain databases

Gene3Di2.60.120.260, 2 hits
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR002706 Xrcc1_N
PfamiView protein in Pfam
PF01834 XRCC1_N, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0R0D2_HUMAN
AccessioniPrimary (citable) accession number: M0R0D2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again