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Protein
Submitted name:

Kallikrein-11

Gene

KLK11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein-11Imported
Gene namesi
Name:KLK11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000167757.13
HGNCiHGNC:6359 KLK11

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000167757

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500400408419 – 170Sequence analysisAdd BLAST152

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiM0QZI8
PRIDEiM0QZI8

Expressioni

Gene expression databases

BgeeiENSG00000167757 Expressed in 136 organ(s), highest expression level in ectocervix
ExpressionAtlasiM0QZI8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0QZI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 170Peptidase S1InterPro annotationAdd BLAST156

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

M0QZI8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRILQLILLA LATGLVGGET RIIKGFECKP HSQPWQAALF EKTRLLCGAT
60 70 80 90 100
LIAPRWLLTA AHCLKPRYIV HLGQHNLQKE EGCEQTRTAT ESFPHPGFNN
110 120 130 140 150
SLPNKDHRND IMLVKMASPV SITWAVRPLT LSSRCVTAGT SCLISGWGST
160 170
SSPQLRLPHT LRCANITIIE
Length:170
Mass (Da):18,787
Last modified:April 3, 2013 - v1
Checksum:i0E548390C2557D03
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UBX7KLK11_HUMAN
Kallikrein-11
KLK11 PRSS20, TLSP, UNQ649/PRO1279
282Annotation score:
M0R151M0R151_HUMAN
Kallikrein related peptidase 11 iso...
KLK11 TLSP
109Annotation score:
M0QZV0M0QZV0_HUMAN
Kallikrein-11
KLK11
68Annotation score:
M0QYW4M0QYW4_HUMAN
Kallikrein-11
KLK11
141Annotation score:
A0A0A0MR55A0A0A0MR55_HUMAN
Kallikrein-11
KLK11
116Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei170Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011473 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000598799; ENSP00000470574; ENSG00000167757
UCSCiuc061bvv.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011473 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0QZI8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM0QZI8
PRIDEiM0QZI8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000598799; ENSP00000470574; ENSG00000167757
UCSCiuc061bvv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000167757.13
HGNCiHGNC:6359 KLK11
OpenTargetsiENSG00000167757
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862

Miscellaneous databases

ChiTaRSiKLK11 human

Gene expression databases

BgeeiENSG00000167757 Expressed in 136 organ(s), highest expression level in ectocervix
ExpressionAtlasiM0QZI8 baseline and differential

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QZI8_HUMAN
AccessioniPrimary (citable) accession number: M0QZI8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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