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Protein
Submitted name:

Epithelial membrane protein 3

Gene

EMP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Epithelial membrane protein 3Imported
Gene namesi
Name:EMP3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000142227.10
HGNCiHGNC:3335 EMP3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 86HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000142227

PTM / Processingi

Proteomic databases

PeptideAtlasiM0QZ66
PRIDEiM0QZ66

Expressioni

Gene expression databases

BgeeiENSG00000142227 Expressed in 205 organ(s), highest expression level in leukocyte
ExpressionAtlasiM0QZ66 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0QZ66
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IY40 Eukaryota
ENOG4111MF9 LUCA
GeneTreeiENSGT00510000046328

Family and domain databases

InterProiView protein in InterPro
IPR003934 EMP_3
IPR004031 PMP22/EMP/MP20/Claudin
IPR004032 PMP22_EMP_MP20
PANTHERiPTHR10671:SF8 PTHR10671:SF8, 1 hit
PfamiView protein in Pfam
PF00822 PMP22_Claudin, 1 hit
PRINTSiPR01456 EPMEMPROT3
PROSITEiView protein in PROSITE
PS01221 PMP22_1, 1 hit
PS01222 PMP22_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

M0QZ66-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLLLLVVSA LHILILILLF VATLDKSWWT LPGKESLNLW YDCTWNNDTK
60 70 80
TWACSNVSEN GWLKAVQVLM VLSLILCCLS FILFMFQLY
Length:89
Mass (Da):10,270
Last modified:October 5, 2016 - v8
Checksum:iA48DFAA9EAD5ABAB
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P54852EMP3_HUMAN
Epithelial membrane protein 3
EMP3 YMP
163Annotation score:
M0QXS0M0QXS0_HUMAN
Epithelial membrane protein 3
EMP3
94Annotation score:
M0R1L9M0R1L9_HUMAN
Epithelial membrane protein 3
EMP3
56Annotation score:
M0R122M0R122_HUMAN
Epithelial membrane protein 3
EMP3
63Annotation score:
M0QXN1M0QXN1_HUMAN
Epithelial membrane protein 3
EMP3
161Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei89Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008392 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000599704; ENSP00000470331; ENSG00000142227
UCSCiuc061asl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008392 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0QZ66
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiM0QZ66
PRIDEiM0QZ66

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000599704; ENSP00000470331; ENSG00000142227
UCSCiuc061asl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000142227.10
HGNCiHGNC:3335 EMP3
OpenTargetsiENSG00000142227
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IY40 Eukaryota
ENOG4111MF9 LUCA
GeneTreeiENSGT00510000046328

Gene expression databases

BgeeiENSG00000142227 Expressed in 205 organ(s), highest expression level in leukocyte
ExpressionAtlasiM0QZ66 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003934 EMP_3
IPR004031 PMP22/EMP/MP20/Claudin
IPR004032 PMP22_EMP_MP20
PANTHERiPTHR10671:SF8 PTHR10671:SF8, 1 hit
PfamiView protein in Pfam
PF00822 PMP22_Claudin, 1 hit
PRINTSiPR01456 EPMEMPROT3
PROSITEiView protein in PROSITE
PS01221 PMP22_1, 1 hit
PS01222 PMP22_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QZ66_HUMAN
AccessioniPrimary (citable) accession number: M0QZ66
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 35 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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